43 research outputs found

    Risk factors and causes of stillbirths among pregnant women in Pakistan

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    Background: Globally 3 million stillbirths occur per year, and Pakistan is ranked 3rd among the countries having the highest burden. Despite being a major public health problem, efforts to reduce this figure are insufficient.Objective: The aim of the study was to identify and measure the inequalities in stillbirth associated risk factors, causes and fertility risk behaviors.Methods: Data were derived from the Pakistan Demographic and Health Surveys (PDHS) 1990-2013. Inequalities on determi- nants were evaluated using rate differences and rate ratios; time trends computed with annualized reduction rate (ARR).Results: Overall ARR determined for stillbirth was -12.52 percent per annum. The high ARR were recorded for mothers age <20, urban areas, educated mothers and for highest wealth quintile. The relative inequalities were most pronounced for wealth quintiles, education and age of mothers. Stillbirth causes were unexplained antepartum (33%), unexplained intrapartum (21%), intrapartum asphyxia (21%) and antepartum maternal disorders (19%). The high fertility risk behavior was found in mothers with age >34 and birth order >3.Conclusion: The study concluded that to achieve gain in child survival, there is need to promote antenatal care, birth spacing, and family planning programs in developing countries.Keywords: Perinatal mortality, stillbirth causes, delivery complications, Pakistan

    Biological Monitoring of Blood Naphthalene Levels as a Marker of Occupational Exposure to PAHs among Auto-Mechanics and Spray Painters in Rawalpindi

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    <p>Abstract</p> <p>Background</p> <p>Routine exposure to chemical contaminants in workplace is a cause for concern over potential health risks to workers. In Pakistan, reports on occupational exposure and related health risks are almost non-existent, which reflects the scarce availability of survey data and criteria for determining whether an unsafe exposure has occurred. The current study was designed to evaluate blood naphthalene (NAPH) levels as an indicator of exposure to polycyclic aromatic hydrocarbons (PAHs) among automobile workshop mechanics (MCs) and car-spray painters (PNs). We further determined the relationship between blood NAPH levels and personal behavioural, job related parameters and various environmental factors that may further be associated with elevated risks of occupational exposures to PAHs.</p> <p>Methods</p> <p>Sixty blood samples (n = 20 for each group i.e. MC, PN and control group) were collected to compare their blood NAPH levels among exposed (MCs and PNs) and un-exposed (control) groups. Samples were analyzed using high pressure liquid chromatography (HPLC). Data regarding demographic aspects of the subjects and their socioeconomic features were collected using a questionnaire. Subjects were also asked to report environmental hygiene conditions of their occupational environment.</p> <p>Results</p> <p>We identified automobile work areas as potential sites for PAHs exposure, which was reflected by higher blood NAPH levels among MCs. Blood NAPH levels ranged from 53.7 to 1980.6 μgL<sup>-1 </sup>and 54.1 to 892.9 μgL<sup>-1 </sup>among MCs and PNs respectively. Comparison within each group showed that smoking enhanced exposure risks several fold and both active and passive smoking were among personal parameters that were significantly correlated with log-transformed blood NAPH levels. For exposed groups, work hours and work experience were job related parameters that showed strong associations with the increase in blood NAPH levels. Poor workplace hygiene and ventilation were recognized as most significant predictors related to differences among workplaces that may enhance the extent of exposure to chemical contaminants.</p> <p>Conclusions</p> <p>It appeared that chemical exposure at the workplace may be influenced by multiple environmental factors, but poor workplace hygiene and duration of exposure (long work hours) were the most important factors. Smoking and negligence of workers regarding self protection were among some of the important personal behaviours than can be addressed with better training. There is also a need to improve workplaces hygiene and to rationalize work hours to minimize health risks. Since smoking was an important confounding factor that supplemented most of the actual occupational exposure, a study based on non-smoker subjects is needed to separate out the effects of smoking and other confounding factors that may obscure measurements of actual extent of occupational exposure.</p

    Risk factors and causes of stillbirths among pregnant women in Pakistan

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    Background: Globally 3 million stillbirths occur per year, and Pakistan is ranked 3rd among the countries having the highest burden. Despite being a major public health problem, efforts to reduce this figure are insufficient. Objective: The aim of the study was to identify and measure the inequalities in stillbirth associated risk factors, causes and fertility risk behaviors. Methods: Data were derived from the Pakistan Demographic and Health Surveys (PDHS) 1990-2013. Inequalities on determinants were evaluated using rate differences and rate ratios; time trends computed with annualized reduction rate (ARR). Results: Overall ARR determined for stillbirth was -12.52 percent per annum. The high ARR were recorded for mothers age &lt;20, urban areas, educated mothers and for highest wealth quintile. The relative inequalities were most pronounced for wealth quintiles, education and age of mothers. Stillbirth causes were unexplained antepartum (33%), unexplained intrapartum (21%), intrapartum asphyxia (21%) and antepartum maternal disorders (19%). The high fertility risk behavior was found in mothers with age &gt;34 and birth order &gt;3. Conclusion: The study concluded that to achieve gain in child survival, there is need to promote antenatal care, birth spacing, and family planning programs in developing countries. DOI: https://dx.doi.org/10.4314/ahs.v19i1.24 Cite as: Afshan K, Narjis G, M Q. Risk factors and causes of stillbirths among pregnant women in Pakistan. Afri Health Sci. 2019;19(1). 1507-1516. https://dx.doi.org/10.4314/ahs.v19i1.2

    Ulnar dimelia variant: a case report

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    We report a case of ulnar dimelia, commonly called mirror hand, in a 2-month-old female child who had restriction of elbow flexion and forearm rotation. There was no facial or other internal organ malformation. Radiographs revealed seven triphalangeal digits with double ulnae (one following the other) and absent radius. To the best of the authors’ knowledge, this is the first report of this mirror hand deformity in which fingers are symmetrical while duplicated ulnae are not

    Introduction of channel catfish Ictalurus punctatus (Rafinesque) in Pakistan and its performance during acclimatization and pond culture.

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    Abstract.-Two thousand fingerlings of channel catfish Ictalurus punctatus were imported from Thailand in a bid to introduce this fish in Pakistan. Five percent mortality occurred during transportation. Experiments were designed to observe catfish acclimatization in tanks or raceways for which five hundred fingerlings (average weight 10.86±1.20g) were placed in five tanks of 2000-liter water capacity and another 500 fingerlings (average weight, 10.56±0.68g) were kept in five raceways of 5000-liter water capacity each. The fish were fed on imported diet for a period of 75 days. Mean weight gain of 27.22±1.75 g and 31.5±1.04 g and surv~7.5% and 95.9% were recorded in tanks and raceways, respectively. For studying growth of fish two stocking densities (3,000 and 3,500/ha) were maintained in ponds (0.04 ha) from December 2003 -November 2004. The weight gain was significantly higher in low stocking density (1,263.3 ± 60.9 g) compared with high stocking density (1,184.9±57.1 g). Fish production and survival between two stocking densities was not different (P&gt;0.05)
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