Optimisation de la fermentation lactique pour l'épuration et la valorisation du lactoserum

National audienc

Uptake of hydrophobic amino acids and sodium chloride by a strong cation exchanger: Application to desalting and separation by preparative liquid chromatography

International audienc

Lactose continuous fermentation with cells recycled by ultrafiltration and lactate separation by electrodialysis: Model identification

International audienceAn off-line parameter estimation method has been developed to predict the dynamic behaviour of a continuous lactose fermentation system. The model used is an unstructured model taking into account cell growth, substrate consumption, and metabolite production (lactic acid). This method, based on the Hooke-Jeeves non-linear-programming technique, results in a good estimation of the biological parameters of the model, and so gives a better understanding of the different phenomena involved in lactose fermentation

Lactose continuous fermentation with cells recycled by ultrafiltration and lactate separation by electrodialysis: Model identification

International audienceAn off-line parameter estimation method has been developed to predict the dynamic behaviour of a continuous lactose fermentation system. The model used is an unstructured model taking into account cell growth, substrate consumption, and metabolite production (lactic acid). This method, based on the Hooke-Jeeves non-linear-programming technique, results in a good estimation of the biological parameters of the model, and so gives a better understanding of the different phenomena involved in lactose fermentation

Lactose continuous fermentation with cells recycled by ultrafiltration and lactate separation by electrodialysis; II: Modelling and simulation

International audienceDynamic modelling of a continuous lactose fermentation system for control and optimisation of operation has been carried out. The bioreactor used was coupled with an ultrafiltration module and an electrodialysis unit. A unstructured model taking into account cell growth, substrate consumption, and metabolite (lactic acid) production, has been analysed. The metabolite production model was represented by the Luedeking-Piret equation, modified in order to improve the description of lactic acid production at low dilution rate

Lactose continuous fermentation with cells recycled by ultrafiltration and lactate separation by electrodialysis; II: Modelling and simulation

International audienceDynamic modelling of a continuous lactose fermentation system for control and optimisation of operation has been carried out. The bioreactor used was coupled with an ultrafiltration module and an electrodialysis unit. A unstructured model taking into account cell growth, substrate consumption, and metabolite (lactic acid) production, has been analysed. The metabolite production model was represented by the Luedeking-Piret equation, modified in order to improve the description of lactic acid production at low dilution rate