60 research outputs found
Thermodynamic basis of intragroup separation of Pr and Nd in the chloride melts employing liquid gallium-tin electrodes
ΠΠ±ΡΠ΅ΠΊΡΠΎΠΌ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΡΠ²Π»ΡΡΡΡΡ ΠΆΠΈΠ΄ΠΊΠΎΠΌΠ΅ΡΠ°Π»Π»ΠΈΡΠ΅ΡΠΊΠΈΠ΅ Π΄Π²ΡΡ
ΡΠ°Π·Π½ΡΠ΅ (Π+ΠΠΠ‘) ΠΈ Π³ΠΎΠΌΠΎΠ³Π΅Π½Π½ΡΠ΅ ΡΠΏΠ»Π°Π²Ρ ΠΏΡΠ°Π·Π΅ΠΎΠ΄ΠΈΠΌΠ° ΠΈ Π½Π΅ΠΎΠ΄ΠΈΠΌΠ° Ρ ΡΠ²ΡΠ΅ΠΊΡΠΈΡΠ΅ΡΠΊΠΈΠΌ ΡΠ°ΡΠΏΠ»Π°Π²ΠΎΠΌ Ga-Sn. Π¦Π΅Π»Ρ ΡΠ°Π±ΠΎΡΡ β ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΡΠ΅ΡΠΌΠΎΠ΄ΠΈΠ½Π°ΠΌΠΈΡΠ΅ΡΠΊΠΈΡ
Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊ ΠΏΡΠ°Π·Π΅ΠΎΠ΄ΠΈΠΌΠ° ΠΈ Π½Π΅ΠΎΠ΄ΠΈΠΌΠ° Π² ΡΠ²ΡΠ΅ΠΊΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠΏΠ»Π°Π²Π°Ρ
Ga-Sn Π² ΡΠ΅ΠΌΠΏΠ΅ΡΠ°ΡΡΡΠ½ΠΎΠΌ Π΄ΠΈΠ°ΠΏΠ°Π·ΠΎΠ½Π΅ 573 1073 Π. Π ΠΎΡΡΠ΅ΡΠ΅ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ Π°Π½Π°Π»ΠΈΠ· Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΠ½ΡΡ
Π΄Π°Π½Π½ΡΡ
ΠΎΠ± Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ, ΠΊΠΎΡΡΡΠΈΡΠΈΠ΅Π½ΡΠ°Ρ
Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΈ ΡΠ°ΡΡΠ²ΠΎΡΠΈΠΌΠΎΡΡΠΈ ΠΏΡΠ°Π·Π΅ΠΎΠ΄ΠΈΠΌΠ° ΠΈ Π½Π΅ΠΎΠ΄ΠΈΠΌΠ°, Π² ΠΈΠ½Π΄ΠΈΠ²ΠΈΠ΄ΡΠ°Π»ΡΠ½ΡΡ
Π³Π°Π»Π»ΠΈΠΈ ΠΈ ΠΎΠ»ΠΎΠ²Π΅. ΠΡΠ΄Π΅Π»ΡΠ½Π°Ρ Π³Π»Π°Π²Π° ΠΏΠΎΡΠ²ΡΡΠ΅Π½Π° Π°Π½Π°Π»ΠΈΠ·Ρ Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΠ½ΡΡ
Π΄Π°Π½Π½ΡΡ
ΠΎ ΡΠ΅ΡΠΌΠΎΠ΄ΠΈΠ½Π°ΠΌΠΈΡΠ΅ΡΠΊΠΈΡ
Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠ°Ρ
ΠΏΡΠ°Π·Π΅ΠΎΠ΄ΠΈΠΌΠ° ΠΈ Π½Π΅ΠΎΠ΄ΠΈΠΌΠ° Π² ΡΠΏΠ»Π°Π²Π°Ρ
Ρ ΠΈΠ½Π΄ΠΈΠ΅ΠΌ ΠΈ Π²ΠΈΡΠΌΡΡΠΎΠΌ, ΡΠ°ΠΊ ΠΊΠ°ΠΊ Π² ΠΈΠ·ΡΡΠ°Π΅ΠΌΠΎΠΌ ΡΠ΅ΠΌΠΏΠ΅ΡΠ°ΡΡΡΠ½ΠΎΠΌ ΠΈΠ½ΡΠ΅ΡΠ²Π°Π»Π΅ ΡΡΠΈ ΡΠΏΠ»Π°Π²Ρ ΠΌΠΎΠ³ΡΡ Π±ΡΡΡ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½Ρ Π² ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΡΠ»Π΅ΠΊΡΡΠΎΠ΄ΠΎΠ² ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ.Objects of the study are two-phase and homogeneous liquid alloys of praseodymium and neodymium with Ga-Sn eutectic melt. The purpose of investigation is determination of thermodynamic properties of praseodymium and neodymium in the eutectic Ga-Sn alloys at the temperature range 573 1073 K. The report analyzed the published data on the activity, activity coefficient and solubility of praseodymium and neodymium, in gallium and tin. Separate chapter contains analysis of published data on the thermodynamic characteristics of alloys of praseodymium and neodymium with indium and bismuth because such alloys are suitable as reference electrodes at investigated temperatures.ΠΡΠΎΠ³ΡΠ°ΠΌΠΌΠ° ΡΠ°Π·Π²ΠΈΡΠΈΡ Π£ΡΠ€Π£ Π½Π° 2013 Π³ΠΎΠ΄ (ΠΏ.1.2.2.3
Mechanisms of interacting <i>Helicobacter pylori</i> with gastric mucosal epithelium. II. A reaction of gastric epithelium on <i>Helicobacter pylori</i> colonization and persistence
Gastric and duodenal recurrent inflammatory diseases have a high prevalence, but the role played by microbes in its development remained unclear. However, the data published in 1983 by Marshall and Warren about isolating Helicobacter pylori from the stomach mucosa of the patient with gastritis and proposing relevant cultivation methods was the turning point in investigating etiology of the upper digestive tract inflammatory disorders. Moreover, it was shown that the majority of H. pylori spp. are found within the gastric lumen upon colonization, whereas around 20% of them are attached to the epithelial cells in the stomach. In addition, effects of interacting H. pylori with gastric epithelium and activation of some defense mechanisms due to bacterial colonization and spreading were analyzed. It was found that along with triggering pro-inflammatory response induced by proteins VacA as well as phosphorylated/unphosphorylated CagA, wherein the latter is able to induce a set of protective reactions H. pylori disrupts intercellular contacts, affects epithelial cell polarity and proliferation, and activates SHP-2 phosphatase resulting in emerging diverse types of cellular responses. The activation mechanisms for the mitogen-activated protein kinase (MAPK) pathway were discussed. The ability of H. pylori to regulate apoptosis, particularly via its suppression, by expressing ERK kinase and protein MCL1 facilitating bacterial survival in the gastric mucosa as well as beneficial effects related to bacterial circulation on gastric epithelial cell survival elicited by anti-apoptotic factors were also examined. Of note, persistence of H. pylori are mainly determined by activating transcriptional factors including NF-ΞΊB, NFAT, SRF, T-cell lymphoid enhancing factor (TCF/LEF), regulating activity of MCL1 protein, in turn, being one of the main anti-apoptotic factors, as well as induced production of the migration inhibitory factor (MIF). The role of VacA cytotoxin in triggering epithelial cell apoptosis via caspase-mediated pathways was also considered. Infection with H. pylori is accompanied by release of proinflammatory cytokine cocktail detected both in vitro and in vivo. In particular, bacterial urease activating transcriptional factor NF-ΞΊB was shown to play a crucial role in inducing cytokine production. Moreover, such signaling pathways may be activated after H. pylori is attached to the cognate receptor in the gastric epithelial surface by interacting with CD74 and MHC class II molecules. Finally, a role for various CD4+ T cell subsets, particularly type 17 T helper cells (Th17) in inducing immune response against H. pylori antigens in gastric mucosa was revealed were also discussed
SURGICAL TREATMENT OF ANEURYSMAL PELVIC BONE CYSTS IN CHILDREN
The outcomes of evaluation and treatment of 9 patients aged from 3 to 17 years with aneurismal Ilium cysts (AIC) are described. All patients with AIC were operated in a stage of delimitation. A surgical technique including an open removal of abnormal tissue with replacing a formed bone defect with an osteoplastic materialin isolation or in combination with an unfreebone graft out of iliac crest was applied for treatment. Recurrence of the pathological process was not observed in any case. Inactive residual cavities were found in 3 patients. 6 patients demonstrated complete organotypic restructuring of allografts in the zone of surgery. Application of a wedge resection of the pathological focus accompanied by post-resection defect grafting with a mix of cortical and demineralized allografts, localization of aneurysmal cyst in the ilium wing, and performing combined bone grafting to treat a pathological focus located in over-acetabular area, demonstrated favorable outcomes in a 4-year follow-up
COMBINATION OF DISTRACTION OSTEOSYNTHESIS AND BONE PLASTIC AT TREATMENT OF CHILDREN WITH CONGENITAL LOW LIMB-LENGTH DISCREPANCY
Research objective was the estimation of combination distraction osteosynthesis with bone plastic in treatment of children with congenital lower limb discrepancy. Results of surgical treatment of 26 children (17 girl and 9 boys) with congenital lower limb-length discrepancy are analyzed. The method consists in creation of superfluous osteogenesis in the field of prospective lengthening. The control group included 10 patients with whom lengthening was carried out by typical way. Results: at the analysis of roentgenograms faster formation of a new bone has been revealed in basic group (on the average for 7,8 days faster on each centimetre of lengthening). Combination of distraction osteosynthesis and combined bone plastics shortened the treatment period by accelerating new bone regeneration during distraction osteogenesis of the children with congenital low limb-length discrepancy
Evolution of a Large-Scale Agglomeration Labour Market (Based on the Example of the Krasnoyarsk Agglomeration)
The article presents a methodical solution of the problem of Krasnoyarsk agglomeration labour market
research in compliance with OECD methodology, under deficiency of official statistical information
on municipalities. Besides that, we analysed the tendencies of Krasnoyarsk agglomeration labour
market within the period from 1999 to 2011, examined territorial asymmetry of the agglomeration
labour market and came to the conclusion on the way this asymmetry influences the dynamics of the
labour market key indicators.Π ΡΡΠ°ΡΡΠ΅ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½ΠΎ ΠΌΠ΅ΡΠΎΠ΄ΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΡΠ΅ΡΠ΅Π½ΠΈΠ΅ ΠΏΡΠΎΠ±Π»Π΅ΠΌΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΡΡΠ½ΠΊΠ° ΡΡΡΠ΄Π°
ΠΡΠ°ΡΠ½ΠΎΡΡΡΠΊΠΎΠΉ Π°Π³Π»ΠΎΠΌΠ΅ΡΠ°ΡΠΈΠΈ Π² ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²ΠΈΠΈ Ρ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ»ΠΎΠ³ΠΈΠ΅ΠΉ ΠΠΠ‘Π Π² ΡΡΠ»ΠΎΠ²ΠΈΡΡ
Π΄Π΅ΡΠΈΡΠΈΡΠ°
ΠΎΡΠΈΡΠΈΠ°Π»ΡΠ½ΠΎΠΉ ΡΡΠ°ΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΈ ΠΏΠΎ ΠΌΡΠ½ΠΈΡΠΈΠΏΠ°Π»ΡΠ½ΡΠΌ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡΠΌ.
ΠΡΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Ρ ΡΠ΅Π½Π΄Π΅Π½ΡΠΈΠΈ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ ΡΡΠ½ΠΊΠ° ΡΡΡΠ΄Π° ΠΡΠ°ΡΠ½ΠΎΡΡΡΠΊΠΎΠΉ Π°Π³Π»ΠΎΠΌΠ΅ΡΠ°ΡΠΈΠΈ
Π·Π° ΠΏΠ΅ΡΠΈΠΎΠ΄ Ρ 1999 ΠΏΠΎ 2011 Π³ΠΎΠ΄. Π Π°ΡΡΠΌΠΎΡΡΠ΅Π½Π° ΠΏΡΠΎΡΡΡΠ°Π½ΡΡΠ²Π΅Π½Π½Π°Ρ Π°ΡΠΈΠΌΠΌΠ΅ΡΡΠΈΡ ΡΡΠ½ΠΊΠ° ΡΡΡΠ΄Π°
Π°Π³Π»ΠΎΠΌΠ΅ΡΠ°ΡΠΈΠΈ ΠΈ ΡΠ΄Π΅Π»Π°Π½Ρ Π²ΡΠ²ΠΎΠ΄Ρ ΠΎ Π΅Ρ Π²Π»ΠΈΡΠ½ΠΈΠΈ Π½Π° ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠΈ ΠΊΠ»ΡΡΠ΅Π²ΡΡ
ΠΈΠ½Π΄ΠΈΠΊΠ°ΡΠΎΡΠΎΠ²
ΡΡΠ½ΠΊΠ° ΡΡΡΠ΄Π°
Mechanisms of interacting Helicobacter pylori with gastric mucosal epithelium. II. A reaction of gastric epithelium on Helicobacter pylori colonization and persistence
Β© 2019 Saint Petersburg Pasteur Institute. All rights reserved. Gastric and duodenal recurrent inflammatory diseases have a high prevalence, but the role played by microbes in its development remained unclear. However, the data published in 1983 by Marshall and Warren about isolating Helicobacter pylori from the stomach mucosa of the patient with gastritis and proposing relevant cultivation methods was the turning point in investigating etiology of the upper digestive tract inflammatory disorders. Moreover, it was shown that the majority of H. pylori spp. are found within the gastric lumen upon colonization, whereas around 20% of them are attached to the epithelial cells in the stomach. In addition, effects of interacting H. pylori with gastric epithelium and activation of some defense mechanisms due to bacterial colonization and spreading were analyzed. It was found that along with triggering pro-inflammatory response induced by proteins VacA as well as phosphorylated/unphosphorylated CagA, wherein the latter is able to induce a set of protective reactions H. pylori disrupts intercellular contacts, affects epithelial cell polarity and proliferation, and activates SHP-2 phosphatase resulting in emerging diverse types of cellular responses. The activation mechanisms for the mitogen-activated protein kinase (MAPK) pathway were discussed. The ability of H. pylori to regulate apoptosis, particularly via its suppression, by expressing ERK kinase and protein MCL1 facilitating bacterial survival in the gastric mucosa as well as beneficial effects related to bacterial circulation on gastric epithelial cell survival elicited by anti-apoptotic factors were also examined. Of note, persistence of H. pylori are mainly determined by activating transcriptional factors including NF-ΞΊB, NFAT, SRF, T-cell lymphoid enhancing factor (TCF/LEF), regulating activity of MCL1 protein, in turn, being one of the main anti-apoptotic factors, as well as induced production of the migration inhibitory factor (MIF). The role of VacA cytotoxin in triggering epithelial cell apoptosis via caspase-mediated pathways was also considered. Infection with H. pylori is accompanied by release of proinflammatory cytokine cocktail detected both in vitro and in vivo. In particular, bacterial urease activating transcriptional factor NF-ΞΊB was shown to play a crucial role in inducing cytokine production. Moreover, such signaling pathways may be activated after H. pylori is attached to the cognate receptor in the gastric epithelial surface by interacting with CD74 and MHC class II molecules. Finally, a role for various CD4+ T cell subsets, particularly type 17 T helper cells (Th17) in inducing immune response against H. pylori antigens in gastric mucosa was revealed were also discussed
Mechanisms of interacting Helicobacter pylori with gastric mucosal epithelium. II. A reaction of gastric epithelium on Helicobacter pylori colonization and persistence
Β© 2019 Saint Petersburg Pasteur Institute. All rights reserved. Gastric and duodenal recurrent inflammatory diseases have a high prevalence, but the role played by microbes in its development remained unclear. However, the data published in 1983 by Marshall and Warren about isolating Helicobacter pylori from the stomach mucosa of the patient with gastritis and proposing relevant cultivation methods was the turning point in investigating etiology of the upper digestive tract inflammatory disorders. Moreover, it was shown that the majority of H. pylori spp. are found within the gastric lumen upon colonization, whereas around 20% of them are attached to the epithelial cells in the stomach. In addition, effects of interacting H. pylori with gastric epithelium and activation of some defense mechanisms due to bacterial colonization and spreading were analyzed. It was found that along with triggering pro-inflammatory response induced by proteins VacA as well as phosphorylated/unphosphorylated CagA, wherein the latter is able to induce a set of protective reactions H. pylori disrupts intercellular contacts, affects epithelial cell polarity and proliferation, and activates SHP-2 phosphatase resulting in emerging diverse types of cellular responses. The activation mechanisms for the mitogen-activated protein kinase (MAPK) pathway were discussed. The ability of H. pylori to regulate apoptosis, particularly via its suppression, by expressing ERK kinase and protein MCL1 facilitating bacterial survival in the gastric mucosa as well as beneficial effects related to bacterial circulation on gastric epithelial cell survival elicited by anti-apoptotic factors were also examined. Of note, persistence of H. pylori are mainly determined by activating transcriptional factors including NF-ΞΊB, NFAT, SRF, T-cell lymphoid enhancing factor (TCF/LEF), regulating activity of MCL1 protein, in turn, being one of the main anti-apoptotic factors, as well as induced production of the migration inhibitory factor (MIF). The role of VacA cytotoxin in triggering epithelial cell apoptosis via caspase-mediated pathways was also considered. Infection with H. pylori is accompanied by release of proinflammatory cytokine cocktail detected both in vitro and in vivo. In particular, bacterial urease activating transcriptional factor NF-ΞΊB was shown to play a crucial role in inducing cytokine production. Moreover, such signaling pathways may be activated after H. pylori is attached to the cognate receptor in the gastric epithelial surface by interacting with CD74 and MHC class II molecules. Finally, a role for various CD4+ T cell subsets, particularly type 17 T helper cells (Th17) in inducing immune response against H. pylori antigens in gastric mucosa was revealed were also discussed
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