Mass media and repulsive interactions in continuous-opinion dynamics

This letter focus on the effect of repulsive interactions on the adoption of an external message in an opinion model. With a simple change in the rules, we modify the Deffuant \emph{et al.} model to incorporate the presence of repulsive interactions. We will show that information receptiveness is optimal for an intermediate fraction of repulsive links. Using the master equation as well as Monte Carlo simulations of the message-free model, we identify the point where the system becomes optimally permeable to external influence with an order-disorder transition

The Triumph of Tagalog and the Dominance of the Discourse on English: Language Politics in the Philippines during the American Colonial Period

Ph.DDOCTOR OF PHILOSOPH

Recognizing and Anticipating Stress Related Complacent Behavior in the Manufacturing Industries

Numerous safety studies suggest that stress complacency related accidents in manufacturing industries continue to cause injuries or fatalities because of the absence of emotional resources for leaders, who are unable to prevent accidents when these conditions exist. Leaders of the manufactory industries may not have the appropriate emotional measures which are significant to recognize employees’ underlying complacent behavior. The purpose of this quantitative correlational study was to evaluate the relationship between leaders’ emotional intelligence resources and their ability to recognize stressful employees thus, prevent injuries and fatalities in the workplace. The research questions address key traits of emotional intelligence regarding emotional perceptions and control which are needed to make the leaders more effective at recognizing and responding to stress complacency related incidents. Specifically, this study includes a method of inquiry in the form of a survey designed to measure 140 leaders’ emotional intelligence competencies in 3 Western Virginia food and beverage manufactories. Structural equation modeling was used to determine the multivariate relationships among leaders’ skills and safety prevention. Leaders’ emotional intelligence results indicated a negative effect on stress identification in either upper or middle leadership groups preventing them from exercising safe prevention error with their employees. Promoting leaders’ emotional intelligence engagement may potentially contribute to social change helping the food and beverage organizations to protect their employees from getting hurt, promoting strong safety cultures, maintaining a positive impact on families and workers and thereby, increasing community resilience

Epigenome wide association study in peripheral blood of pregnant women identifies potential metabolic pathways related to gestational diabetes

Gestational diabetes mellitus (GDM) increases the risk of developing metabolic disorders in both pregnant women and their offspring. Factors such as nutrition or the intrauterine environment may play an important role, through epigenetic mechanisms, in the development of GDM. The aim of this work is to identify epigenetic marks involved in the mechanisms or pathways related to gestational diabetes. A total of 32 pregnant women were selected, 16 of them with GDM and 16 non-GDM. DNA methylation pattern was obtained from Illumina Methylation Epic BeadChip, from peripheral blood samples at the diagnostic visit (26–28 weeks). Differential methylated positions (DMPs) were extracted using ChAMP and limma package in R 2.9.10, with a threshold of FDR |5|% and B >0. A total of 1.141 DMPs were found, and 714 were annotated in genes. A functional analysis was performed, and we found 23 genes significantly related to carbohydrate metabolism. Finally, a total of 27 DMPs were correlated with biochemical variables such as glucose levels at different points of oral glucose tolerance test, fasting glucose, cholesterol, HOMAIR and HbA1c, at different visits during pregnancy and postpartum. Our results show that there is a differentiated methylation pattern between GDM and non-GDM. Furthermore, the genes annotated to the DMPs could be implicated in the development of GDM as well as in alterations in related metabolic variables.Juan Rodes program from "Instituto de Salud Carlos III" JR20-00040Miguel Servet Type I program from the ISCIII-Madrid, Spain CP20/00066Ministerio de trabajo y economia social de Espana FI19/00178 POEJ-0039-18Junta de Andalucia RC-0008-2021Centros de Investigacion Biomedica en Red" (CIBER) of the Institute of Health Carlos III (ISCIII) CB06/03/0018Instituto de Salud Carlos III PI18/01175 PI21/01864)Junta de Andalucia PI-0283-2018 PI-0419-2019European Commissio

Epigenetic marks associated with gestational diabetes mellitus across two time points during pregnancy

An adverse intrauterine or periconceptional environment, such as hyperglycemia during pregnancy, can affect the DNA methylation pattern both in mothers and their offspring. In this study, we explored the epigenetic profile in maternal peripheral blood samples through pregnancy to find potential epigenetic biomarkers for gestational diabetes mellitus (GDM), as well as candidate genes involved in GDM development. We performed an epigenome-wide association study in maternal peripheral blood samples in 32 pregnant women (16 with GDM and 16 non-GDM) at pregnancy week 24–28 and 36–38. Biochemical, anthropometric, and obstetrical variables were collected from all the participants. The main results were validated in an independent cohort with different ethnic origin (European = 307; South Asians = 165). Two hundred and seventy-two CpGs sites remained significantly different between GDM and non-GDM pregnant women across two time points during pregnancy. The significant CpG sites were related to pathways associated with type I diabetes mellitus, insulin resistance and secretion. Cg01459453 (SELP gene) was the most differentiated in the GDM group versus non-GDM (73.6 vs. 60.9, p = 1.06E−11; FDR = 7.87E−06). Three CpG sites (cg01459453, cg15329406, and cg04095097) were able to discriminate between GDM cases and controls (AUC = 1; p = 1.26E−09). Three differentially methylated positions (DMPs) were replicated in an independent cohort. To conclude, epigenetic marks during pregnancy differed between GDM cases and controls suggesting a role for these genes in GDM development. Three CpGs were able to discriminate GDM and non-GDM groups with high specificity and sensitivity, which may be biomarker candidates for diagnosis or prediction of GDM.Juan Rodes program from "Instituto de Salud Carlos III" JR20-00040Miguel Servet Type I program from the ISCIII-Madrid, Spain CP20/00066PFIS program FI19/00178Ministerio de trabajo y economia social de EspanaGarantia Juvenil program POEJ-0039-18Junta de Andalucia RC-0008-2021Centros de Investigacion Biome-dica en Red" (CIBER)Institute of Health Carlos III (ISCIII) CB06/03/0018Spanish Government PI18/01175 PI21/01864Servicio Andaluz de Salud," PI-0283-2018 PI-0419-2019European Union (EU

Derivatización de nanoclústeres de oro protegidos por tioprina

II Encuentro sobre nanociencia y nanotecnología de investigadores y tecnólogos de la Universidad de Córdoba. NANOUC

Formación de bioconjugados de nanopartículas de oro con la proteina albúmina

III Encuentro sobre Nanociencia y Nanotecnología de Investigadores y Tecnólogos Andaluce

Addressing the potential for improvement of urban building stock: a protocol applied to a Mediterranean Spanish case

Current plans to combat the environmental global impact of the building sector have encouraged research on sustainable actions for increasing the renovation rate of many buildings whose performance is far from meeting current energy standards. This paper presents a protocol for analysing the existing residential stock towards planning building upgrading actions. A Geographic Information System with building-related data is used to assess the housing stock following a bottom-up approach. The urban study sample is established using several criteria at building level. The potential for improvement of buildings is ascertained using DOE 2.2 energy models which incorporate standard passive strategies to reduce the current primary energy demand and the associated CO2 emissions. The protocol is applied to the existing public housing developments built in the southern Spanish city of Córdoba, under Mediterranean conditions, during the urban expansion period which spanned 1951–1980. The extrapolation of results to the urban study sample shows a 25 % reduction in CO2 emissions and a 40 % decrease in annual energy demand. Furthermore, the impact of typology and position on the energy behaviour of a given building is acknowledged. The benefits achieved aim to help stakeholders in the implementation of energy retrofitting urban plans

Intercambio de ligando en nanopartículas de Au protegidas por monocapas de mercaptopurina

III Encuentro sobre Nanociencia y Nanotecnología de Investigadores y Tecnólogos Andaluce