Needs Assessment Using Community-Based Collaborative Action Research in an American Indian Community

Community-Based Collaborative Action Research (CBCAR) holds promise when conducting nursing research in Native American communities. This article identifies through review of the literature common issues inherent in conducting traditional research in Native American Communities. The purpose of this article is to share first steps in implementing community- based collaborative action research in a Native American community. It addresses not only issues identified by the community but also provides insight into the future use of CBCAR in other Native American communities

A study of health and nursing services in greater Lowell, Massachusetts

Thesis (Ed.M.)--Boston University, 1950. This item was digitized by the Internet Archive

A study of the coorientation of high school principals, journalism teachers, and local news media representatives in selected Iowa communities

This research studies the orientations of selected Iowa high school journalism teachers, high school principals and newspaper editors toward issues of high school Journalism Studies; The issues of high school journalism that became the objects of the coorientation study are the value of high school journalism to the high school student, the rights and responsibilities of the high school journalist, and the roles of partners in a high school journalism and news media partnership;The impetus for the study comes from previous studies showing a climate of isolation between the high school journalism program and the professional news media, from recent reports on education in the United States calling for closer ties between education and industry, and from a very recent surge of interest in high school journalism demonstrated by the professional news media and college and university journalism programs;The perspective for the study comes from the coorientation model of communication and the variables for study are agreement, congruency, and accuracy. The selected respondents were asked to respond on a Likert-type scale to statements representing the value of high school journalism, the rights and responsibilities of student journalists, and the roles of partners. A oneway analysis of variance shows the three respondent groups are cooriented toward the roles of partners in a high school journalism/media partnership. High school principals and newspaper editors are cooriented on the value of high school journalism and on the rights of high school Journalism Studies;With few exceptions, t-test results show that the respondent groups do not demonstrate congruency or accuracy when asked to predict the responses of members of the other respondent groups. The respondents do not often perceive the others to be in agreement with them about the issues of high school journalism and they do not, as a rule, accurately predict the actual responses of the other respondent groups

Sludge Under Suspicion: Explaining Perceptions of Risks from a Relatively Unknown Technology

Factors such as knowledge about the technology and trust in technology-generating institutions influenced people\u27s decisions about the acceptability of applying treated sludge on Iowa\u27s agricultural lands

Cholesterol Conjugated HDAC Inhibitor as Novel Anticancer Agent

Histone deacetylase (HDAC) inhibitors are a class of promising new multifunctional anticancer agents. These agents are able to affect multiple epigenetic changes in aberrant cells. In addition to regulating the gene expression and transcription via chromatin remodeling, HDAC inhibitors can also modulate a variety of cellular functions including proliferation, differentiation, and apoptosis. Vorinostat (SuberAniloHydroxamic Acid, SAHA), the first HDAC inhibitor approved by FDA, inhibited the metastasis of various cancer cells. However, SAHA distributes in cancer tissue and normal tissue in a similar level. It will be ideal to selectively delivery SAHA into cancer cells. Rapidly growing cancer cells have a great need for cholesterol to generate new membranes. Increased low-density lipoprotein (LDL)-uptake by tumor cells has been found. LDL is the major cholesterol carrier in plasma and its uptake is mediated by the LDL-receptor (LDL-R), a glycoprotein overexpressed on the surface of cancer cells. Cholesterol can be used as a delivery agent to enhance anti-cancer drugs penetrating cancer cell membrane via LDL-R. Degradation of LDL particles by endosomal enzymes will result in the release of the conjugates to target cancer cells. Herein, we designed and synthesized SAHA cholesterol conjugate, and tested the anticancer activity of SAHA and its conjugate. The results suggest that cancer cells uptake more cholesterol SAHA conjugate when the culture medium does not contain LDL. Based on the information, we will design and generate artificial LDL containing SAHA cholesterol conjugate to enhance the drug delivery.https://engagedscholarship.csuohio.edu/u_poster_2014/1028/thumbnail.jp

Evaluation of Job Benefits of Members of the American Agricultural Editors Association

The Communication Clinic Committee of the American Agricultural Editors Association (AAEA), in cooperation with the Iowa State University Department of Journalism and Mass Communication, surveyed AAEA members to determine salaries, fringe benefits, and satisfaction with benefits