A graphical environment for change detection in structured documents

Change detection in structured documents (e.g. SGML is important in data warehousing, digital libraries and Internet databases. This thesis presents a graphical environment for detecting changes in the structured documents. We represent. each document by alp ordered labeled tree based on the underlying markup language. We then compare two documents by invoking previously developed algorithms for approximate pattern matching and pattern discovery in trees. Several operators are developed to support. the comparison of the documents; graphical devices are provided to facilitate the use of the operators. We believe the proposed tool is useful for not only document management, but also software maintenance, particularly configuration management and version control, where programs aro represented as parse trees and detecting changes in the trees provides a way to find the syntactic differences of two program versions

Team Effectiveness and Project Management in a Student Team Environment

The objective of this research study was to assess if students enrolled in MSU - Mankato\u27s Automotive Engineering Technology (AET) program required a project management course. At present, a project management course is not included in the AET program. A survey instrument based on The Team Effectiveness Critique by Susan Trimble was developed to answer the research question. AET students enrolled in Senior Design courses were the main focus of this study. Survey results indicated that AET Senior Design students who had taken a project management course prior to a Senior Design course had good ratings in survey categories of Trust and Conflict, Goals and Objectives, and Communication. Findings of this research study indicated that a project management course might help enhance the overall experience of an AET Senior Design project

Some applications of randomized algorithms for control system design

In this paper a few “difficult” problems related to simultaneous stabilization of three plants (equivalent to a certain problem related to unit interpolation in H∞) have been addressed through the framework of randomized algorithms. These problems which were proposed by Blondel (Simultaneous Stabilization of Linear Systems, Springer, Berlin, 1994) and Blondel and Gevers (Math. Control Signals Systems 6 (1994) 135) concern the existence of a controller

CLINICAL EVALUATION OF AYURVEDIC FORMULATION OF COLICARMIN PLUS SYRUP ON COLIC, GRIPING PAIN, INDIGESTION, NAUSEA, VOMITING, AND OTHER DIGESTIVE DISORDERS IN PAEDIATRICS AND GERIATRICS PATIENTS.

ABSTRACTObjective: An open label study to assess the effect of colicarmin plus syrup on colic and griping pain, indigestion, nausea and vomiting in children,and geriatric patients.Methods: (a) A study was conducted on 75 number of patients to evaluate the effect of colicarmin plus syrup on colic and griping pain, indigestion,nausea and vomiting in children, and adults, (b) mostly these children were selected from different classes of families, (c) all the patients were checkedon the 1st, 2nd, and 3rd week after starting the therapeutic dose.Dosage schedule: (a) Children: 1 Teaspoonful thrice a day after meals, (b) adults: 2 Teaspoonful twice to thrice a day after meals.Results: (a) Colic and griping pain: In the total duration of treatment, no of patients recovering were 23-on 1st week, 4-on 2 week,overall result is 93.54%, (b) indigestion: In the total duration of treatment, no of patients recovering were 26-on 1stnd week, and 3-on 3 week, 3-on 2 week, and 1-on3rd week, the overall result is 93.75%, (c) nausea and vomiting: In the total duration of treatment, no of patients recovering were 8-on 1 week, 2-on2nd week, and 1-on 3rd week, the overall result is 91.33%.Conclusion: Based on the study, we can conclude that colicarmin plus syrup is an Ayurvedic formulation with benefits such as digestive, carminative,anthelmintic, antiflatulent, antispasmodic, and devoid of side effects.Keywords: Digestive, Carminative, Anthelmintic, Antiflatulent and Antispasmodic.ndstr

Inhibitive action of Bridelia retusa leaves extract on corrosion of mild steel in acidic media

Extract of Bridelia retusa leaves was investigated as corrosion inhibitor of mild steel in 1 N H2SO4 using conventional weight loss, electrochemical polarizations, electrochemical impedance spectroscopy and scanning electron microscopic studies. The weight loss results showed that the extract of Bridelia retusa leaves is excellent corrosion inhibitor and electrochemical polarizations data revealed the mixed mode of inhibition. While the results of electrochemical impedance spectroscopy have shown that the change in the impedance parameters, charge transfer resistance and double layer capacitance, with the change in concentration of the extract is due to the adsorption of active molecules leading to the formation of a protective layer on the surface of mild steel. Scanning electron microscopic studies provided the confirmatory evidence of improved surface condition, due to the adsorption, for the corrosion protection

Chemopreventive Herbal Anti-Oxidants: Current Status and Future Perspectives

Cancer chemoprevention is fast becoming a lucrative approach for controlling cancer. Carcinogenesis being a complex multi-step, multi-factorial process, a number of chemopreventive interventions can be employed. These strategies are generally directed against two broad events of carcinogenesis viz., initiation and promotion/progression. Anti-initiation interventions principally involve inhibition of carcinogen activation, scavenging of free radicals and reactive carcinogen metabolites along with enhanced detoxification of carcinogens by modulating cellular metabolism. Anti-promotion strategies involve attenuation of enhanced cellular proliferation along with induction of cellular apoptosis and differentiation. Dietary agents or herbal anti-oxidants due to low toxicity and relative safety are promising chemopreventive agents. These agents after emerging successful through a series of in vitro and in vivo assays enter clinical trials. Many dietary compounds have emerged as promising chemopreventive agents in empirical experiments. However, in clinical trials these compounds have met with limited success. This emphasizes the need for further detailed research on the mechanisms of observed chemoprevention and choice, dose, duration and bioavailability of chemopreventive agent used. Complex issues such as choice and nutritional status of target population, genetic variation, gene-environment interactions and relevance of biomarkers analyzed also warrant further research and analyses

Identification and Comparative Analysis of Subolesin/Akirin Ortholog from Ornithodoros turicata Ticks

Background: Subolesin is an evolutionary conserved molecule in diverse arthropod species that play an important role in the regulation of genes involved in immune responses, blood digestion, reproduction and development. In this study, we have identified a subolesin ortholog from soft ticks Ornithodoros turicata, the vector of the relapsing fever spirochete in the United States. Methods: Uninfected fed or unfed O. turicata ticks were used throughout this study. The subolesin mRNA was amplified by reverse transcription polymerase chain reaction (RT-PCR) and sequenced. Quantitative-real time PCR (QRT-PCR) was performed to evaluate subolesin mRNA levels at different O. turicata developmental stages and from salivary glands and gut tissues. Bioinformatics and comparative analysis was performed to predict potential post-translational modifications in O. turicata subolesin amino-acid sequences. Results: Our study reveals that O. turicata subolesin gene expression is developmentally regulated, where; adult ticks expressed significantly higher levels in comparison to the larvae or nymphal ticks. Expression of subolesin was evident in both unfed and fed ticks and in the salivary glands and midgut tissues. The expression of subolesin transcripts varied in fed ticks with peak levels at day 14 post-feeding. Phylogenetic analysis revealed that O. turicata subolesin showed a high degree of sequence conservation with subolesin’s from other soft and hard ticks. Bioinformatics and comparative analysis predicted that O. turicata subolesin carry three Protein kinase C and one Casein kinase II phosphorylation sites. However, no myristoylation or glycosylation sites were evident in the O. turicata subolesin sequence. Conclusion: Our study provides important insights in recognizing subolesin as a conserved potential candidate for the development of a broad-spectrum anti-vector vaccine to control not only ticks but also several other arthropods that transmit diseases to humans and animals

Sferični kristali celekoksiba za poboljšanje topljivosti, oslobađanja i mikromeričnih svojstava

Celecoxib spherical agglomerates were prepared with polyvinylpyrrolidone (PVP) using acetone, water and chloroform as solvent, non-solvent and bridging liquid, respectively. The agglomerates were characterized by differential scanning calorimetry (DSC), X-ray diffraction (XRD), IR spectroscopic studies and scanning electron microscopy (SEM). The IR spectroscopy and DSC results indicated the absence of any interactions between drug and additives. XRD studies showed a decrease in crystallinity in agglomerates. The crystals exhibited significantly improved micromeritic properties compared to pure drug. The loading efficiency (% or mg drug per 100 mg crystals) was in the range of 93.9 ± 2.3 and 97.3 ± 1.3% (n = 3), with all formulations. The aqueous solubility and dissolution rate of the drug from crystals was significantly (p < 0.05) increased (nearly two times). The solubility and in vitro drug release rates increased with an increase in PVP concentration (from 2.5 to 10%). The SEM studies showed that the crystal possesses a good spherical shape with smooth and regular surface.U radu je opisana priprava sferičnih aglomerata sa celekoksibom koristeći polivinilpirolidon (PVP), aceton, vodu i kloroform. Aglomerati su karakterizirani diferencijalnom pretražnom kalorimetrijom (DSC), rentgenskom difrakcijom (XRD), IR spektroskopijom i pretražnom elektronskom mikroskopijom (SEM). IR i DSC su pokazale odsutnost bilo kakvih interakcija između ljekovite tvari i aditiva. XRD je pokazala smanjenje kristaliničnosti u aglomeratima. Aglomerati su pokazali značajno poboljšana mikromerična svojstva u odnosu na čisti lijek. Udio lijeka u njima bio je između 93.89 ± 2.26 i 97.32 ± 1.29%. Topljivost u vodi i oslobađanje ljekovite tvari iz aglomerata povećalo se skoro dva puta. Topljivost i in vitro oslobađanje se povećava s povećanjem koncentracije PVP (od 2,5 do 10%). SEM studije su pokazale da kristali imaju pravilan sferični oblik te glatku i pravilnu površinu

Sferični kristali celekoksiba za poboljšanje topljivosti, oslobađanja i mikromeričnih svojstava

Celecoxib spherical agglomerates were prepared with polyvinylpyrrolidone (PVP) using acetone, water and chloroform as solvent, non-solvent and bridging liquid, respectively. The agglomerates were characterized by differential scanning calorimetry (DSC), X-ray diffraction (XRD), IR spectroscopic studies and scanning electron microscopy (SEM). The IR spectroscopy and DSC results indicated the absence of any interactions between drug and additives. XRD studies showed a decrease in crystallinity in agglomerates. The crystals exhibited significantly improved micromeritic properties compared to pure drug. The loading efficiency (% or mg drug per 100 mg crystals) was in the range of 93.9 ± 2.3 and 97.3 ± 1.3% (n = 3), with all formulations. The aqueous solubility and dissolution rate of the drug from crystals was significantly (p < 0.05) increased (nearly two times). The solubility and in vitro drug release rates increased with an increase in PVP concentration (from 2.5 to 10%). The SEM studies showed that the crystal possesses a good spherical shape with smooth and regular surface.U radu je opisana priprava sferičnih aglomerata sa celekoksibom koristeći polivinilpirolidon (PVP), aceton, vodu i kloroform. Aglomerati su karakterizirani diferencijalnom pretražnom kalorimetrijom (DSC), rentgenskom difrakcijom (XRD), IR spektroskopijom i pretražnom elektronskom mikroskopijom (SEM). IR i DSC su pokazale odsutnost bilo kakvih interakcija između ljekovite tvari i aditiva. XRD je pokazala smanjenje kristaliničnosti u aglomeratima. Aglomerati su pokazali značajno poboljšana mikromerična svojstva u odnosu na čisti lijek. Udio lijeka u njima bio je između 93.89 ± 2.26 i 97.32 ± 1.29%. Topljivost u vodi i oslobađanje ljekovite tvari iz aglomerata povećalo se skoro dva puta. Topljivost i in vitro oslobađanje se povećava s povećanjem koncentracije PVP (od 2,5 do 10%). SEM studije su pokazale da kristali imaju pravilan sferični oblik te glatku i pravilnu površinu