Multi-cultural, multi-course collaborative project: Learning outcomes and project impact

A multi-course collaborative project is an effective way to enhance student learning because it not only facilitates the development of social skills, but also provides students an opportunity to understand the importance of collaboration with people in diverse areas in the industry (Kim, LaFleur, & Schaeffer, 2008). A collaborative project in a multi-cultural setting enhances student learning by exposing students to other cultures and broadening their scope of knowledge and applications (Chen, Hsu, & Caropreso, 2006)

In Vivo Fluorescence Imaging of Bacteriogenic Cyanide in the Lungs of Live Mice Infected with Cystic Fibrosis Pathogens

10.1371/journal.pone.0021387PLoS ONE67

Multilingual Noun Dictionary: Korean-Indonesian-Arabic-English

이 책은 한국어를 학습하는 외국인 학생들이 한국어 어휘부에서 가장 중요한 위치를 차지하는 명사(Noun)의 의미를 습득하고 이해하는 데에 도움을 주기 위하여 만들어졌다. 외국인 학습자에 있어 특히 ‘인도네시 아어’, ‘몽골어’, ‘아랍어’를 모국어로 하는 학습자들이 자신들의 모국어 와의 대역어를 통해 한국어 명사의 의미를 이해할 수 있도록 설계되었 다. 주어진 외국어 어휘의 의미를 이해하기 위하여 자신의 모국어로의 번역을 수행하는 작업은 해당 어휘의 의미를 습득하기 위한 가장 직접 적이고 자연스러운 방식의 하나이기 때문이다

Multi-cultural, multi-course collaborative project: Learning outcomes and project impact

A multi-course collaborative project is an effective way to enhance student learning because it not only facilitates the development of social skills, but also provides students an opportunity to understand the importance of collaboration with people in diverse areas in the industry (Kim, LaFleur, & Schaeffer, 2008). A collaborative project in a multi-cultural setting enhances student learning by exposing students to other cultures and broadening their scope of knowledge and applications (Chen, Hsu, & Caropreso, 2006).</p

Building Korean linguistic resource for NLU data generation of banking app CS dialog system

International audienceNatural language understanding (NLU) is integral to task-oriented dialog systems, but demands a considerable amount of annotated training data to increase the coverage of diverse utterances. In this study, we report the construction of a linguistic resource named FIAD (Financial Annotated Dataset) and its use to generate a Korean annotated training data for NLU in the banking customer service (CS) domain. By an empirical examination of a corpus of banking app reviews, we identified three linguistic patterns occurring in Korean request utterances: TOPIC (ENTITY, FEATURE), EVENT, and DISCOURSE MARKER. We represented them in LGGs (Local Grammar Graphs) to generate annotated data covering diverse intents and entities. To assess the practicality of the resource, we evaluate the performances of DIET-only (Intent: 0.91 /Topic [entity+feature]: 0.83), DIET+ HANBERT (I:0.94/T:0.85), DIET+ KoBERT (I:0.94/T:0.86), and DIET+ KorBERT (I:0.95/T:0.84) models trained on FIAD-generated data to extract various types of semantic items

Long term renal outcome after hypertensive disease during pregnancy: a nationwide population-based study

Objective Hypertensive disease during pregnancy increases the risk of maternal morbidity and mortality and leads to the development of multi-organ dysfunction, including kidney dysfunction. Complicated pregnancies require careful postpartum management to prevent sequelae. It is believed that kidney injury can consistently occur even after delivery; therefore, defining the chronicity and endpoint is essential for establishing diagnostic criteria. However, data on the prevalence of persistent renal complications following hypertensive disease during pregnancy are limited. In this study, we evaluated the risk of developing renal disorders in patients with a history of hypertensive disease during pregnancy. Methods Participants who gave birth between 2009 and 2010 were followed up for 8 years after delivery. The risk of renal disorder development after delivery was determined according to a history of hypertensive disease during pregnancy. Different factors that could affect the course of pregnancy, including age, primiparity, multiple pregnancy, preexisting hypertension, pregestational diabetes, hypertensive disease during pregnancy, gestational diabetes, postpartum hemorrhage, and cesarean section, were adjusted for using the Cox hazard model. Results Women with hypertension during pregnancy had a higher risk of developing renal disorders after delivery (0.23% vs. 1.38%; P<0.0001). This increased risk remained significant even after adjusting for covariates (adjusted hazard ratio, 3.861; 95% confidence interval [CI], 3.400–4.385] and 4.209 [95% CI, 3.643–4.864]; respectively). Conclusion Hypertension during pregnancy can contribute to the development of renal disorders, even after delivery

Genetic and immune microenvironment characterization of HER2‐positive gastric cancer: Their association with response to trastuzumab‐based treatment

Abstract Background We aimed to determine the molecular and immune microenvironment characteristics of HER2‐positive gastric cancer (GC) related to the patient's response to first‐line trastuzumab‐based treatment. Methods Eighty‐three cases of HER2‐positive advanced gastric adenocarcinoma patients treated with trastuzumab were enrolled. Targeted deep sequencing and transcriptome analysis were performed on selected 21 cases (exploration cohort) along with two post‐treatment samples. The results were compared between patients progressed before 6 months (Group 2) and others (Group 1), and were validated by FISH and immunohistochemistry in total cohort. Tumor‐infiltrating immune cells were evaluated using RNA sequencing data and multiplex immunohistochemistry. Progression‐free survival (PFS) analysis was performed. Results Group 1 showed frequent amplification of G1/S cell cycle checkpoint‐related genes and upregulated KEGG pathways related to cell proliferation. In contrast, Group 2 had more frequent EGFR, HER3, and MET amplification and higher RNA expression in immune‐related KEGG pathways than Group 1. In total cohort, significant predictors of better PFS were cell cycle‐related including CCNE1 amplification, Cyclin A and PLK1 overexpression, and decreased Cyclin D3 and HER3 expression (p < 0.05), or immune‐related including high density of CD3−CD57+ NK cells and PD‐L1 combined positive score ≥5 (p < 0.05). The best prognostic predictors were a combination of Cyclin A, Cyclin E, p21, and HER3 (p < 0.001). Conclusion HER2‐positive GC with favorable response to trastuzumab were characterized by cell cycle‐related gene alterations and increased CD3−CD57+ NK cell infiltration. These findings would be helpful to the fine modulation of therapeutic strategies for patients with HER2‐positive GC