7 research outputs found

    Digital Libraries in Open Education: the Italy case,

    Get PDF
    Open Education strategies, and specifically MOOC (Massive Open Online Courses) and OER (Open Educational Resources), play an important role in supporting policies for educational innovation, lifelong learning, and, more generally, the enlargement of educational opportunities for all. While there is an increasing interest in Open Education, there is little awareness about the role of Digital Library as learning incubators for learning enhancement. The paper presents briefly the state of art of Digital libraries in the light of the most recent initiatives of Open Education in Italy, towards an integrated model of Digital libraries as “knowledge and learning open hubs”

    The application of cortical layer markers in the evaluation of cortical dysplasias in epilepsy

    Get PDF
    The diagnostic criteria for focal cortical dysplasia type I (FCD I) remain to be well and consistently defined. Cortical layer-specific markers (CLM) provide a potential tool for the objective assessment of any dyslamination. We studied expression patterns of recognised CLM using immunohistochemistry for N200, ER81, Otx1, Map1b (subsets of V/VI projection neurones), Pax6, Tbr1, Tbr2 (differentially expressed in cortical neurones from intermediate progenitor cells), Cux 1 (outer cortical layers) and MASH1 (ventricular zone progenitors). Dysplasia subtypes included FCD I and II, dysplasias adjacent to hippocampal sclerosis (HS) or dysembryoplastic neuroepithelial tumours (DNTs); all were compared to neonatal and adult controls. Laminar expression patterns in normal cortex were observed with Tbr1, Map1b, N200 and Otx1. FCDI cases in younger patients were characterised by abnormal expression in layer II for Tbr1 and Otx1. FCDII showed distinct labelling of balloon cells (Pax6, ER81 and Otx1) and dysmorphic neurones (Tbr 1, N200 and Map1b) supporting origins from radial glia and intermediate progenitor cells, respectively. In temporal lobe sclerosis cases with dysplasia adjacent to HS, Tbr1 and Map1b highlighted abnormal orientation of neurones in layer II. Dyslamination was not confirmed in the perilesional cortex of DNT with CLM. Finally, immature cell types (Otx1, Pax6 and Tbr2) were noted in varied pathologies. One possibility is activation of progenitor cell populations which could contribute to the pathophysiology of these lesions

    EDOS: Environment for the Development and Distribution of Open Source Software

    No full text
    International audienceThe open-source software community is now comprised of a very large and growing number of contributors and users. The GNU/Linux operating system for instance has an estimated 18 million users worldwide and its contributing developers can be counted by thousands. The critical mass of contributors taking part in various opensource projects has helped to ensure high quality for open source software. However, despite the achievements of the open-source software industry, there are issues in the production of large scale open-source software (OSS) such as the GNU/Linux operating system that have to be addressed as the numbers of users, of contributors, and of available applications grow. EDOS is a European project supported by IST started October 2004 and ending in 2007, whose objective is to provide a new generation of methodologies, theoretical models, technical tools and quality models specifically tailored to OSS engineering and to software distribution over the Internet

    EDOS: Environment for the Development and Distribution of Open Source Software

    No full text
    Abstract – The open-source software community is now comprised of a very large and growing number of contributors and users. The GNU/Linux operating system for instance has an estimated 18 million users worldwide and its contributing developers can be counted by thousands. The critical mass of contributors taking part in various open-source projects has helped to ensure high quality for open source software. However, despite the achievements of the open-source software industry, there are issues in the production of large scale open-source software (OSS) such as the GNU/Linux operating system that have to be addressed as the numbers of users, of contributors, and of available applications grow. EDOS is a European project supported by IST started October 2004 and ending in 2007, whose objective is to provide a new generation of methodologies, theoretical models, technical tools and quality models specifically tailored to OSS engineering and to software distribution over the Internet
    corecore