The damaging effect of consuming fermented Oryza sativa var. glutinosa on the pancreatic organ

The damaging effect of consuming fermented Oryza sativa var. glutinosa on Pancreatic Organ. Tuak is one of the alcoholic drinks made using recipes from the ancestors of the Dayak tribe in the West Kalimantan region. Tuak is commonly consumed especially at traditional ceremonies and holidays. Some studies report that consuming alcoholic drinks negatively impacts health. This study aimed to examine the effect of consuming tuak on blood glucose levels and histopathology of the pancreatic organ. Male mice were grouped into four groups, ten mice each. Group A was negative control (no administered tuak), group B, C, and D were administered tuak at dose 0.26 mL/20 g body weight per day for 7, 14, and 21 consecutive days. Compared to the negative control, the administration of tuak at different time spans showed anincrease in blood glucose levels (P<0.05) and in the scoring lesion of the pancreatic organ (P <0.05). It is concluded that the pancreatic organ damage that occurred due to repeated use of tuak is accompanied by increasing blood glucose levels

PEMBUATAN MEDIA E-KOMIK PADA SUB MATERI ZAT ADITIF

Abstrak: Penelitian ini bertujuan  untuk mengetahui kelayakan e-komik sebagai media pembelajaran pada sub materi zat aditif. Metode yang digunakan dalam penelitian ini adalah penelitian deskriptif dengan bentuk penelitian survei. Instrumen penelitian yang digunakan dalam penelitian ini adalah lembar validasi. Kelayakan media e-komik di ukur melalui uji validitas oleh 8 orang validator yang terdiri atas 3 orang validator ahli media dan 5 orang validator ahli materi. Berdasarkan analisis data, media e-komik pada sub materi zat aditif dinyatakan layak digunakan sebagai media pembelajaran dengan nilai rata-rata validasi ahli media sebesar 3,24 dan validasi ahli materi sebesar 3,34. Kata kunci :Media E-komik, Sub Materi Zat Aditif   Abstract: This study aimed to determine the feasibility of e-comics as a learning media in additive sub material. The method used in this research was descriptive survey form. The research instrument used the validation sheet. The feasibility of e-comics media was measured through test validity by 8 validators that consist of 3 media expert validators and 5 material expert validators. Based on data analysis, e-comic media in additive sub material is feasible as a learning media with an average value of media expert validation at 3.24 and materials expert validation at 3.34. Keywords: E-comics Media, Sub Material Additiv

EFEKTIVITAS MODEL THINK PAIR SHARE DISERTAI FLIPBOOK TERHADAP HASIL BELAJAR PADA MATERI PROTISTA

The purpose of this research is to determine effectiviness of TPS model accompained by flipbook media to ward study result at material Protista in class X SMA Negeri 1 Sanggau Ledo. The research was a Quasy Experimental with Nonequivalent control group design. The sample of this research are XE as experiment class and XB as control class. The instrument been used was multiple choice test that consists of 20 items. Average study result that had been TPS model accompained by flipbook media 15,03 was higher by those using conventional teaching 13,90. The U Mann Whitney test obtained Zcount< -Ztable that is -2,52 < -1,96, meaning that there were significant differences between study result that taught by TPS model accompained by flipbook media and conventional learning. Value of Effect Size obtained 0,48 is medium, meaning the use TPS model accompained by flipbook media effectively improve study result at material protista. Keywords: Cooperative Learning, Flipbook Media, Study Result

HEPATOPROTECTIVE ACIVITY OF THE ETHANOLIC EXTRACT OF DOG FRUIT RIND (Pithecellobium lobatum Benth.)

The present study was conducted to investigate the hepatoprotective activity of ethanolic extract of dog fruit rind (Pithecellobium lobatum benth.) against carbon tetrachloride (CCl4) induced hepatotoxicity in rats. Male Wistar albino rats were randomly divided into four groups and administered orally with 50 mg/200 g body weight of dog fruit rind extract (K1), 100 mg/200 g body weight (K2) of dog fruit rind extract, 5 mg/200 g body weight of silymarin (K3/positive control), and 0.4 mL/200 g body weight of distilled water (K4/negative control), for seven days The levels of alanine transaminase (ALT) of each K1; K2; K3; and K4 were 143.40±83.75 U/L, 94.80±93.77 U/L, 130.20±58.54 U/L and 147.25±107.97 U/L, respectively, while the aspartate transaminase (AST) levels were 304.20±128.67 U/L; 213.20±88.93 U/L; 333.00±128.31 U/L; and 239.25 ± 94.90 U/L, respectively (P0.05). Group K2 showed better histological pattern than other groups with 60% of mild and 40% of moderate liver damage. Our findings revealed the hepatoprotective activity of the ethanolic extract of dog fruit rind

The damaging effect of consuming fermented Oryza sativa var. glutinosa on the pancreatic organ

444-448The damaging effect of consuming fermented Oryza sativa var. glutinosa on Pancreatic Organ. Tuak is one of the alcoholic drinks made using recipes from the ancestors of the Dayak tribe in the West Kalimantan region. Tuak is commonly consumed especially at traditional ceremonies and holidays. Some studies report that consuming alcoholic drinks negatively impacts health. This study aimed to examine the effect of consuming tuak on blood glucose levels and histopathology of the pancreatic organ. Male mice were grouped into four groups, ten mice each. Group A was negative control (no administered tuak), group B, C, and D were administered tuak at dose 0.26 mL/20 g body weight per day for 7, 14, and 21 consecutive days. Compared to the negative control, the administration of tuak at different time spans showed anincrease in blood glucose levels (P<0.05) and in the scoring lesion of the pancreatic organ (P <0.05). It is concluded that the pancreatic organ damage that occurred due to repeated use of tuak is accompanied by increasing blood glucose levels

GANGGUAN FUNGSI HATI INDUK BUNTING AKIBAT PEMBERIAN KARBON TETRAKLORIDA

Tujuan penelitian ini adalah mengetahui gangguan fungsi hati yang terjadi akibat pemberian karbon tetraklorida (CCl4) pada berbagai tingkatan dosis terhadap induk bunting. Karbon tetraklorida dosis tunggal 0,014 dan 0,14 ml/20 g bobot badan mencit diberikan secara intraperitoneum pada mencit bunting, lalu diamati kerusakan yang terjadi pada hati. Kerusakan hati ditandai dengan peningkatan kadar enzim alanin transaminase (ALT), aspartat transaminase (AST) dalam serum, dan gambaran histopatologi hati. Dibandingkan dengan kont rol, pemberian CCl4 dosis 0,014 ml/20 g bobot badan mengakibatkan peningkatan ALT dan AST, bahkan pada dosis 0,14 ml/20 g bobot badan mengakibatkan induk mati dalam waktu kurang dari 24 jam setelah perlakuan. Gambaran histopatologis sel-sel hati pada kelompok mencit bunting yang mendapatkan CCl4 0,014 ml/20 g bobot badan menunjukkan terjadinya steatosis. Dapat disimpulkan bahwa pemberian karbon tetraklorida pada induk bunting menimbulkan kerusakan seiring peningkatan dosis yang diinduksikan, bahkan berakibat kematian

UPAYA MENINGKATKAN HASIL BELAJAR SISWA MENGGUNAKAN MODEL KOOPERATIF TIPE STUDENT TEAMS ACHIEVEMEN DIVISION DI SMP

Abstrak: Penelitian ini bertujuan untuk meningkatkan hasil belajar siswa dengan menggunakan model kooperatif tipe STAD pada materi sistem peredaran darah manusia di kelas VIII B SMP Negeri 2 Siantan. Bentuk penelitian ini adalah penelitian tindakan kelas. Sampel penelitian siswa kelas VIII B dengan jumlah siswa 24 orang, 12 laki-laki dan 12 orang perempuan. Penelitian ini dilakukan dalam dua siklus. Dari hasil penelitian, rata-rata hasil belajar pada siklus 1 sebesar 76,6 dengan ketuntasan 87,5% dan siklus 2 sebesar 82,41 dengan ketuntasan 100% (KKM 65). Persentase pelaksanaan pembelajaran pada siklus 1 sebesar 100% dan siklus 2 sebesar 100%. Dapat disimpulkan bahwa dengan menggunakan model kooperatif tipe STAD dapat meningkatkan hasil belajar siswa pada materi sitem peredaran darah manusia.   Kata kunci: Kooperatif tipe STAD, hasil belajar.   Abstract: This study aims to improve  the students’ learning result by using the cooperative model type STAD on the material of  the human blood circulation system in VIII B class of SMP Negeri 2 Siantan. The model of this study was Classroom Action Research. The samples are the students of VIII B class which is consist of 24 students, 12 boys and 12 girls. This study was conducted in two cycles. Based on the result of the study, obtained that the average of the first cycle result was 76,6 with  87,5% of completeness while the second cycle was 82,41 with 100% of completeness (KKM 65). Since percentage of the learning process on the first cyle was 100% and the second cycle was 100%, can be concluded that using the cooperative model of STAD type can improve the students learning result on the material of the human blood circulation system.   Keywords: Cooperative type STAD, learning result.  

DEVELOPMENT OF MAGAZINE AS A LEARNING MEDIA ON ENDOCRINE SYSTEM

The magazine is one of the learning media that is rarely used in school. This research aimed to know the feasibility of endocrine system magazines and examine the learners' response to magazines as the media. This type of research is research and development. Five expert judgments tested the feasibility of the magazine. The aspects that were assessed were the material and media aspects. The product trials were done on nine students—the responses measured included cognitive, affective, and conative. The result of this research showed, on the feasible test CVR score of the material and media aspects was 1. Moreover, the CVI score was one as well. On the product trial, the score for cognitive aspect 85,18%, affective 83,33%, conative 87,77%,  and the average responses 85,42%. It can be concluded that endocrine system magazine was feasible as learning media. Furthermore, magazines as a media gained a positive and strong response. So magazines can be a choice of media that can help learning activities