34 research outputs found
Assessing the trophic ecology of three sympatric squid in the marine ecosystem off the Patagonian Shelf by combining stomach content and stable isotopic analyses
Squid species are important components of the Southern Atlantic Ocean ecosystems, as they
prey on a wide range of crustaceans, fish and cephalopods. As a result of this trophic
interaction and their high abundance, they are considered reliable indicators of energy
transfer and biomass in the food web. We identified Illex argentinus, Doryteuthis gahi and
Onykia ingens as the most important squid species interacting on the Patagonian shelf, and
used isotope analysis and stomach content identification to assess the feeding ecology and
interaction of these squids in the ecosystem. Our results describe trophic interactions by
direct predation of O. ingens and I. argentinus on D. gahi, and a trophic overlap of the three
squid, and indicate a higher trophic level and differences in the foraging areas for mature
and maturing D. gahi inferred through δ15N and δ13C concentrations. These differences were
related to the segregation and different habitat of large mature D. gahi and suggest a food
enrichment of C and N based on feeding sources other than those used by small maturing
D. gahi and I. argentinus and O. ingens.Versión del editor1,484
A phase II randomized trial comparing radiotherapy with concurrent weekly cisplatin or weekly paclitaxel in patients with advanced cervical cancer
<p>Abstract</p> <p>Purpose/Objective</p> <p>This is a prospective comparison of weekly cisplatin to weekly paclitaxel as concurrent chemotherapy with standard radiotherapy for locally advanced cervical carcinoma.</p> <p>Materials/Methods</p> <p>Between May 2000 and May 2004, 31 women with FIGO stage IB2-IVA cervical cancer or with postsurgical pelvic recurrence were enrolled into this phase II study and randomized to receive on a weekly basis either 40 mg/m<sup>2 </sup>Cisplatin (group I; 16 patients) or 50 mg/m<sup>2 </sup>paclitaxel (group II; 15 patients) concurrently with radiotherapy. Median total dose to point A was 74 Gy (range: 66-92 Gy) for group I and 66 Gy (range: 40-98 Gy) for group II. Median follow-up time was 46 months.</p> <p>Results</p> <p>Patient and tumor characteristics were similar in both groups. The mean number of chemotherapy cycles was also comparable with 87% and 80% of patients receiving at least 4 doses in groups I and II, respectively. Seven patients (44%) of group I and 8 patients (53%) of group II developed tumor recurrence. The Median Survival time was not reached for Group I and 53 months for group II. The proportion of patients surviving at 2 and 5 years was 78% and 54% for group I and 73% and 43% for group II respectively.</p> <p>Conclusions</p> <p>This small prospective study shows that weekly paclitaxel does not provide any clinical advantage over weekly cisplatin for concurrent chemoradiation for advanced carcinoma of the cervix.</p
Membrane-mediated interactions
Interactions mediated by the cell membrane between inclusions, such as
membrane proteins or antimicrobial peptides, play important roles in their
biological activity. They also constitute a fascinating challenge for
physicists, since they test the boundaries of our understanding of
self-assembled lipid membranes, which are remarkable examples of
two-dimensional complex fluids. Inclusions can couple to various degrees of
freedom of the membrane, resulting in different types of interactions. In this
chapter, we review the membrane-mediated interactions that arise from direct
constraints imposed by inclusions on the shape of the membrane. These effects
are generic and do not depend on specific chemical interactions. Hence, they
can be studied using coarse-grained soft matter descriptions. We deal with
long-range membrane-mediated interactions due to the constraints imposed by
inclusions on membrane curvature and on its fluctuations. We also discuss the
shorter-range interactions that arise from the constraints on membrane
thickness imposed by inclusions presenting a hydrophobic mismatch with the
membrane.Comment: 38 pages, 10 figures, pre-submission version. In: Bassereau P., Sens
P. (eds) Physics of Biological Membranes. Springer, Cha
From Sea to Sea: Canada's Three Oceans of Biodiversity
Evaluating and understanding biodiversity in marine ecosystems are both necessary and challenging for conservation. This paper compiles and summarizes current knowledge of the diversity of marine taxa in Canada's three oceans while recognizing that this compilation is incomplete and will change in the future. That Canada has the longest coastline in the world and incorporates distinctly different biogeographic provinces and ecoregions (e.g., temperate through ice-covered areas) constrains this analysis. The taxonomic groups presented here include microbes, phytoplankton, macroalgae, zooplankton, benthic infauna, fishes, and marine mammals. The minimum number of species or taxa compiled here is 15,988 for the three Canadian oceans. However, this number clearly underestimates in several ways the total number of taxa present. First, there are significant gaps in the published literature. Second, the diversity of many habitats has not been compiled for all taxonomic groups (e.g., intertidal rocky shores, deep sea), and data compilations are based on short-term, directed research programs or longer-term monitoring activities with limited spatial resolution. Third, the biodiversity of large organisms is well known, but this is not true of smaller organisms. Finally, the greatest constraint on this summary is the willingness and capacity of those who collected the data to make it available to those interested in biodiversity meta-analyses. Confirmation of identities and intercomparison of studies are also constrained by the disturbing rate of decline in the number of taxonomists and systematists specializing on marine taxa in Canada. This decline is mostly the result of retirements of current specialists and to a lack of training and employment opportunities for new ones. Considering the difficulties encountered in compiling an overview of biogeographic data and the diversity of species or taxa in Canada's three oceans, this synthesis is intended to serve as a biodiversity baseline for a new program on marine biodiversity, the Canadian Healthy Ocean Network. A major effort needs to be undertaken to establish a complete baseline of Canadian marine biodiversity of all taxonomic groups, especially if we are to understand and conserve this part of Canada's natural heritage