33 research outputs found

    Terremoto del 29 dicembre 2013 nel Matese (MW = 5.0). Indagine speditiva degli effetti nell’area epicentrale e analisi preliminare della sequenza sismica.

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    Il 29 dicembre 2013 un terremoto di magnitudo Mw=5.0 (profondità 10.5 km) è avvenuto nell'area dei Monti del Matese alle ore 18:08:43 ora locale

    General practitioners' deprescribing decisions in older adults with polypharmacy: a case vignette study in 31 countries

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    BACKGROUND: General practitioners (GPs) should regularly review patients' medications and, if necessary, deprescribe, as inappropriate polypharmacy may harm patients' health. However, deprescribing can be challenging for physicians. This study investigates GPs' deprescribing decisions in 31 countries. METHODS: In this case vignette study, GPs were invited to participate in an online survey containing three clinical cases of oldest-old multimorbid patients with potentially inappropriate polypharmacy. Patients differed in terms of dependency in activities of daily living (ADL) and were presented with and without history of cardiovascular disease (CVD). For each case, we asked GPs if they would deprescribe in their usual practice. We calculated proportions of GPs who reported they would deprescribe and performed a multilevel logistic regression to examine the association between history of CVD and level of dependency on GPs' deprescribing decisions. RESULTS: Of 3,175 invited GPs, 54% responded (N = 1,706). The mean age was 50 years and 60% of respondents were female. Despite differences across GP characteristics, such as age (with older GPs being more likely to take deprescribing decisions), and across countries, overall more than 80% of GPs reported they would deprescribe the dosage of at least one medication in oldest-old patients (> 80 years) with polypharmacy irrespective of history of CVD. The odds of deprescribing was higher in patients with a higher level of dependency in ADL (OR =1.5, 95%CI 1.25 to 1.80) and absence of CVD (OR =3.04, 95%CI 2.58 to 3.57). INTERPRETATION: The majority of GPs in this study were willing to deprescribe one or more medications in oldest-old multimorbid patients with polypharmacy. Willingness was higher in patients with increased dependency in ADL and lower in patients with CVD

    Seismic damage and destructive potential of seismic events

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    This paper has been written within a research framework investigating the destructive potential of seismic events. The elastic response spectra seem insufficient to explain the behaviour of structures subject to large earthquakes in which they experience extensive plastic deformations. Recent works emphasise that there were many difficulties in the definition of a single pararneter linked to the destl-uctive potential of an earthquake. In this work a study on the effect of frequency content on structural damage has been carried out. The behaviour of two different elastoplastic oscillators has been analysed, considering several artificial earthquakes. The results obtained suggest a method for evaluating the destructive seismic potential of an earthquake through the response spectra ad the frequency content of the signal. and through the mechai~ical characteristics of the structures within the analysed area

    Vulnerabilità sismica dell'area vesuviana

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    Il volume riporta i risultati del lavoro della Commissione istituita dalla Protezione Civile per la elaborazione di scenari per la valutazione dei rischi vulcanico- sismico connessi all'attività del Vesuvio e per la predisposizione del relativo Piano di Protezione Civile

    Dynamic behavior of masonry structures under pyroclastic flows

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