Is there justification for prophylactic extraction of third molars? A systematic review

Funda??o de Amparo ? Pesquisa do Estado de Minas Gerais (FAPEMIG)Empresa de Pesquisa Agropecu?ria de Minas Gerais (EPAMIG)Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico (CNPq)Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES)The present systematic review was performed to investigate if there is evidence justifying the prophylactic extraction of third molars, one of the most frequent procedures in oral surgery. A series of searches was carried out for randomized, clinical trials and systematic reviews in seven databases (MEDLINE, BBO, LILACS, Web of Science, EMBASE, BIREME and Cochrane Library), with no restrictions regarding year or language. A supplemental manual search of the references of retrieved articles was also performed. The search strategy resulted in 260 papers. Both the data extracted and the quality of each paper were evaluated independently by two reviewers. After selection based on the preestablished eligibility criteria, four papers qualified for the final analysis. A medium degree of quality and methodological consistency was found in three studies, and low quality was found in one study. No studies showed a high degree of consistency. The most significant flaw was an inadequate sample size. The results of the present review indicate a lack of scientific evidence to justify the indication of the prophylactic extraction of third molars

Allergic reactions and nickel-free braces: a systematic review

Nickel-free braces have gained popularity as a viable alternative for patients who are allergic to nickel. The purpose of this systematic review was to determine whether evidence exists to justify the use of nickel-free brackets in orthodontic patients who are allergic to nickel. An electronic search was performed using 7 databases (MEDLINE, BBO, LILACS, Web of Science, EMBASE, BIREME and Cochrane Library), without restriction regarding year or language, with supplemental manual searching of the references of retrieved articles. The search strategy produced 89 papers. The data extraction and quality score of each paper were evaluated independently by two reviewers, once each. After selection based on the eligibility criteria, four papers, including 2 controlled clinical trials and 2 clinical trials, qualified for the final analysis. Quality assessment of the included articles was also performed. Nickel-free braces (Ni content - 2% max.) seem to represent a viable alternative for orthodontic patients who are allergic to nickel. However, further in vivo studies, considering the immunology characteristics of patients, are needed to determine the clinical implications of the findings of this study

Bioactive and biocompatible cement as a single element in pulpotomy of deciduous teeth: a randomized clinical trials

ABSTRACT Objective: Pulpotomy in deciduous teeth maintains the integrity and health of deciduous teeth and supporting tissues until a permanent tooth has erupted. PBS HD CIMMO® cement was evaluated in deciduous teeth pulpotomies as base material and restoration. A randomized clinical trial was performed Methods: This study was approved by the Ethics Committee of (Universidade Vale do Sapucaí) UNIVÁS with Certificate of Presentation for Ethical Consideration, protocol number is: 1.771.929. 60 deciduous molar teeth from 32 healthy children were selected. These teeth were divided into two groups: G1 with 30 teeth, in which the classictreatment with formocresol was used, and G2 with 30 teeth, in which PBS HD CIMMO® cement was used as base and simultaneous final restoration. The evaluation was performed 12 months after the intervention through clinical and radiographic exams. Fisher’s exact test was performed to correlate the clinical and radiographic aspects in both groups Results: There was no significant difference (p= 0.090) in the clinical-radiographic evaluation. PBS HD CIMMO® cement is option to be used as a single element in pulpotomies of deciduous teeth Conclusion: Longitudinal studies should be performed in order to demonstrate a significant association between these groups. The study was enrolled in clinical trials (clinical trials.gov) with registration NCT03200938

Charged-particle multiplicity fluctuations in Pb–Pb collisions at √sNN = 2.76 TeV

Measurements of event-by-event fluctuations of charged-particle multiplicities in Pb–Pb collisions at sNN−−−√ = 2.76 TeV using the ALICE detector at the CERN Large Hadron Collider (LHC) are presented in the pseudorapidity range |η|<0.8 and transverse momentum 0.2<pT<2.0 GeV/c. The amplitude of the fluctuations is expressed in terms of the variance normalized by the mean of the multiplicity distribution. The η and pT dependences of the fluctuations and their evolution with respect to collision centrality are investigated. The multiplicity fluctuations tend to decrease from peripheral to central collisions. The results are compared to those obtained from HIJING and AMPT Monte Carlo event generators as well as to experimental data at lower collision energies. Additionally, the measured multiplicity fluctuations are discussed in the context of the isothermal compressibility of the high-density strongly-interacting system formed in central Pb–Pb collisions