201 research outputs found

    Webmapping in the Etruscan landscape

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    The Etruscan town of Cerveteri and its territory have been investigated since the 1980s by the Istituto di Studi sulle Civiltà Italiche e del Mediterraneo Antico of the Italian CNR, becoming a field of experimentation for computer applications to archaeological surveys and excavations. In recent years, a new multimedia project, aimed at creating an interactive itinerary, has been planned in order to develop the Caeretan information system and experiment with the potentials of new webmapping and webGIS tools. This article gives a general overview of the Italian panorama in this sector of applications and describes the main steps of the itinerary (from the Villa Giulia Etruscan National Museum in Rome to the town of Cerveteri, following the Roman consular road Aurelia) as well as the procedures to be followed for its accomplishment

    La diffusione della cultura scientifica: documentazione e disseminazione nei progetti di ricerca dell’ISMA

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    The article illustrates the main research lines promoted at a national level by Law n. 113/1991, as amended by Law 6/2000, for the dissemination of the scientific culture and the active support and participation of the Accademia Nazionale dei Lincei. As part of this initiative, the main CNR-ISMA projects approved and funded by Ministry of Education, University and Research are then described, including, in particular, the two projects ‘20 years of Archeologia e Calcolatori’ and ‘The Virtual Museum of Archaeological Computing’. They both are intended to offer open access resources for documenting and disseminating archaeological research data

    Informatica archeologica e archeologia digitale. Le risposte dalla rete

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    The article illustrates the most recent achievements of archaeological computing, through a systematic survey that starts with the very name of the discipline, as used at national and international levels. The aim is to examine if the distinction made between ‘archaeological computing’ and ‘digital archaeology’ can really be helpful in framing the discipline in its theoretical and methodological evolution. From the synthesis made, the dominance of technological aspects on the theoretical and methodological approach clearly emerges. For some time now, technology has governed the three main areas of archaeological practice: field work, laboratory analysis and cultural heritage management and promotion. Two other important aspects are today rapidly gaining ground: ‘Communicating archaeological research’ and ‘European digital infrastructures for archaeology’. Finally, particularly significant is the sector of Digital Heritage or Heritage Science, which today seems to be the focus of all digital archaeology involvements

    Scholarly Tracks in Emergency Medicine

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    Over the past decade, some residency programs in emergency medicine (EM) have implemented scholarly tracks into their curricula. The goal of the scholarly track is to identify a niche in which each trainee focuses his or her scholarly work during residency. The object of this paper is to discuss the current use, structure, and success of resident scholarly tracks. A working group of residency program leaders who had implemented scholarly tracks into their residency programs collated their approaches, implementation, and early outcomes through a survey disseminated through the Council of Emergency Medicine Residency Directors (CORD) list-serve. At the 2009 CORD Academic Assembly, a session was held and attended by approximately 80 CORD members where the results were disseminated and discussed. The group examined the literature, discussed the successes and challenges faced during implementation and maintenance of the tracks, and developed a list of recommendations for successful incorporation of the scholarly track structure into a residency program. Our information comes from the experience at eight training programs (five 3-year and three 4-year programs), ranging from 8 to 14 residents per year. Two programs have been working with academic tracks for 8 years. Recommendations included creating clear goals and objectives for each track, matching track topics with faculty expertise, protecting time for both faculty and residents, and providing adequate mentorship for the residents. In summary, scholarly tracks encourage the trainee to develop an academic or clinical niche within EM during residency training. The benefits include increased overall resident satisfaction, increased success at obtaining faculty and fellowship positions after residency, and increased production of scholarly work. We believe that this model will also encourage increased numbers of trainees to choose careers in academic medicine.ACADEMIC EMERGENCY MEDICINE 2010; 17:S87–S94 © 2010 by the Society for Academic Emergency MedicinePeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/79229/1/j.1553-2712.2010.00890.x.pd

    Impiego di un programma integrato di bioattivazione per il controllo della polmonite micoplasmica del suino

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    Introduzione. La qualit\ue0 dell\u2019aria nelle strutture di allevamento dei suini dipende soprattutto dalla concentrazione dei biogas, derivati dall\u2019azione della flora microbica fecale sull\u2019urea contenuta nelle urine; il peggioramento della qualit\ue0 ambientale \ue8 alla base di molti problemi sanitari, basati in primo luogo sull\u2019impossibilit\ue0 degli animali a mantenere un bilancio organico corretto. Una soluzione possibile e innovativa \ue8 rappresentata dalla bioattivazione con miscele batterico-enzimatiche; per questa via, si pu\uf2 ottenere una riduzione delle emanazioni, controllando anche la formazione di sostanze dannose per l\u2019ambiente. Materiali e metodi. \uc8 stato programmato un intervento in due aziende suinicole (il reparto di magronaggio-ingrasso di un ciclo chiuso completo e un allevamento di solo ingrasso), per controllare il danno indotto dall\u2019infezione micoplasmica nelle fasi di produzione a flusso continuo; sono stati messi a confronto gruppi trattati e non trattati, diversi tipi di pavimentazione (grigliato completo, concreto completo e misto grigliato-concreto) e pi\uf9 schemi d\u2019intervento, utilizzando, da soli o in combinazione, bioattivatori in polvere e liquidi. Il sistema di bioattivazione impiegato comprende due bioattivatori (in polvere e soluzione) e un prodotto naturale di origine vegetale da aggiungere alla razione alimentare. La polvere \ue8 stata distribuita sulle pavimentazioni, in ragione di 0,5 Kg per 100 mq ogni 15 giorni mediante spargimento manuale, mentre la soluzione \ue8 stato aerosolizzata nell\u2019ambiente di stabulazione, mediante impianto computerizzato, in ragione di 1 litro ogni 100 mq al mese; il prodotto vegetale, per la sua composizione in grado di riequilibrare la flora intestinale, \ue8 stato invece aggiunto quotidianamente alla razione, in ragione di 500 g/t di mangime. I rilievi e le osservazioni hanno riguardato la concentrazione di azoto ammoniacale (rilevata con metodo chimico), la presenza di anticorpi specifici per M. hyopneumoniae prima e dopo il periodo di trattamento (valutata con metodo ELISA), i punteggi polmonari al macello (valutati con metodo quantitativo) e il peso medio di partita. Risultati. In tutti i gruppi trattati, la sieroprevalenza per M. hyopneumoniae \ue8 stata elevata, a dimostrazione della circolazione dell\u2019infezione nel periodo di osservazione, ma la diminuzione della concentrazione ambientale dell\u2019ammoniaca, ottenuta grazie all\u2019impiego dei bioattivatori) ha permesso di ottenere benefici evidenti sul punteggio polmonare medio, confermati dalla significativit\ue0 statistica delle differenze, e sul peso medio di partita. In rapporto ai tipi di pavimentazione, la bioattivazione ha fornito i risultati migliori combinando polvere e liquido sul grigliato completo. Conclusioni. I risultati ottenuti dimostrano che nelle situazioni di allevamento, la stabilizzazione del bilancio organico degli animali attraverso una gestione ambientale che ne garantisca anche il benessere \ue8 una soluzione attuabile, in una logica di depotenziamento delle infezioni; essi sono la conseguenza dell\u2019accresciuta reattivit\ue0 degli animali, correlata ad un miglior bilancio organico, piuttosto che l\u2019effetto di un\u2019azione diretta sui patogeni; \ue8 in corso la valutazione della reattivit\ue0 immunitaria aspecifica dei suini sottoposti a trattamento, per correlare stato sanitario e produttivit\ue0 al miglioramento della qualit\ue0 ambientale

    Dietary Saccharomyces cerevisiae boulardii CNCM I-1079 positively affects performance and intestinal ecosystem in broilers during a campylobacter jejuni infection

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    In poultry production, probiotics have shown promise to limit campylobacteriosis at the farm level, the most commonly reported zoonosis in Europe. The aim of this trial was to evaluate the effects of Saccharomyces supplementation in Campylobacter jejuni challenged chickens on performance and intestinal ecosystem. A total of 156 day old male Ross 308 chicks were assigned to a basal control diet (C) or to a Saccharomyces cerevisiae boulardii CNCM I-1079 supplemented diet (S). All the birds were orally challenged with C. jejuni on day (d) 21. Live weight and growth performance were evaluated on days 1, 21, 28 and 40. The histology of intestinal mucosa was analyzed and the gut microbiota composition was assessed by 16S rRNA. Performance throughout the trial as well as villi length and crypt depth were positively influenced by yeast supplementation. A higher abundance of operational taxonomic units (OTUs) annotated as Lactobacillus reuteri and Faecalibacterium prausnitzii and a lower abundance of Campylobacter in fecal samples from S compared to the C group were reported. Supplementation with Saccharomyces cerevisiae boulardii can effectively modulate the intestinal ecosystem, leading to a higher abundance of beneficial microorganisms and modifying the intestinal mucosa architecture, with a subsequent improvement of the broilers' growth performance

    Salmonella enterica serovar typhimurium exploits inflammation to modify swine intestinal microbiota

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    Salmonella enterica serovar Typhimurium is an important zoonotic gastrointestinal pathogen responsible for foodborne disease worldwide. It is a successful enteric pathogen because it has developed virulence strategies allowing it to survive in a highly inflamed intestinal environment exploiting inflammation to overcome colonization resistance provided by intestinal microbiota. In this study, we used piglets featuring an intact microbiota, which naturally develop gastroenteritis, as model for salmonellosis. We compared the effects on the intestinal microbiota induced by a wild type and an attenuated S. Typhimurium in order to evaluate whether the modifications are correlated with the virulence of the strain. This study showed that Salmonella alters microbiota in a virulence-dependent manner. We found that the wild type S. Typhimurium induced inflammation and a reduction of specific protecting microbiota species (SCFA-producing bacteria) normally involved in providing a barrier against pathogens. Both these effects could contribute to impair colonization resistance, increasing the host susceptibility to wild type S. Typhimurium colonization. In contrast, the attenuated S. Typhimurium, which is characterized by a reduced ability to colonize the intestine, and by a very mild inflammatory response, was unable to successfully sustain competition with the microbiota

    Mass fractionation of noble gases in synthetic methane hydrate : implications for naturally occurring gas hydrate dissociation

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    This paper is not subject to U.S. copyright. The definitive version was published in Chemical Geology 339 (2013): 242-250, doi:10.1016/j.chemgeo.2012.09.033.As a consequence of contemporary or longer term (since 15 ka) climate warming, gas hydrates in some settings may presently be dissociating and releasing methane and other gases to the ocean–atmosphere system. A key challenge in assessing the impact of dissociating gas hydrates on global atmospheric methane is the lack of a technique able to distinguish between methane recently released from gas hydrates and methane emitted from leaky thermogenic reservoirs, shallow sediments (some newly thawed), coal beds, and other sources. Carbon and deuterium stable isotopic fractionation during methane formation provides a first-order constraint on the processes (microbial or thermogenic) of methane generation. However, because gas hydrate formation and dissociation do not cause significant isotopic fractionation, a stable isotope-based hydrate-source determination is not possible. Here, we investigate patterns of mass-dependent noble gas fractionation within the gas hydrate lattice to fingerprint methane released from gas hydrates. Starting with synthetic gas hydrate formed under laboratory conditions, we document complex noble gas fractionation patterns in the gases liberated during dissociation and explore the effects of aging and storage (e.g., in liquid nitrogen), as well as sampling and preservation procedures. The laboratory results confirm a unique noble gas fractionation pattern for gas hydrates, one that shows promise in evaluating modern natural gas seeps for a signature associated with gas hydrate dissociation.Partial support for this research was provided by Interagency Agreements DE-FE0002911 and DE-NT0006147 between the U.S. Geological Survey Gas Hydrates Project and the U.S. Department of Energy's Methane Hydrates Research and Development Program
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