A comparative stratigraphy of cilicia : Results of the first three cilician chronology workshops

This article presents a preliminary comparative stratigraphy of excavated sites in Plain Cilicia and one in Rough Cilicia. It is the outcome of three workshops held in 2014, 2015 and 2017. Plain Cilicia at the junction of Anatolia, Syro-Mesopotamia and Cyprus is one of the most fertile regions of the Ancient Near East. In recent years, archaeological research in the region has intensified, re-opening questions of chronology. The comparative stratigraphy discussed in the workshops is presented here in form of a gazetteer of the participating sites and a chart. This is to be understood as a first step towards a more comprehensive chronology

Effects of ketamine, thiopental sodium and propofol on muscle contractures in rat diaphragm in vitro

PubMed ID: 1742205The effects of commonly used intravenous anaesthetic agents ketamine, thiopental sodium and propofol on the caffeine-alone or halothane-plus-caffeine-induced muscle contractures were investigated to determine safety for use in patients susceptible to malignant hyperthermia (MH). The muscle strips from rat diaphragm were exposed to one of these anaesthetic agents prior to challenge with caffeine 8 mmol/l alone or halothane 3% plus caffeine 8 mmol/l together. None of the three agents induced contractures when added alone. Ketamine 100 µmol/l and thiopental sodium 300 µmol/l augmented neither caffeine-alone nor caffeine-with-halothane contractures significantly and these two agents appear to be safe for use in MH-susceptible patients. In contrast, propofol 150 µmol/l augmented these contractile responses significantly and may not be recommended for use in patients known to be susceptible to this anaesthetic complication

Effects of ketamine, thiopental sodium and propofol on muscle contractures in rat diaphragm in vitro.

The effects of commonly used intravenous anaesthetic agents ketamine, thiopental sodium and propofol on the caffeine-alone or halothane-plus-caffeine-induced muscle contractures were investigated to determine safety for use in patients susceptible to malignant hyperthermia (MH). The muscle strips from rat diaphragm were exposed to one of these anaesthetic agents prior to challenge with caffeine 8 mmol/l alone or halothane 3% plus caffeine 8 mmol/l together. None of the three agents induced contractures when added alone. Ketamine 100 mumol/l and thiopental sodium 300 mumol/l augmented neither caffeine-alone nor caffeine-with-halothane contractures significantly and these two agents appear to be safe for use in MH-susceptible patients. In contrast, propofol 150 mumol/l augmented these contractile responses significantly and may not be recommended for use in patients known to be susceptible to this anaesthetic complication

System-Level Performance of Cellular Multihop Relaying with Multiuser Scheduling

Abstract — Multihop relaying in cellular networks is seen as a viable strategy to address the need for higher data rates and better coverage. In this paper, we analyze the system-level performance of multicellular multihop networks in the presence of co-channel interference, and build upon prior work in [1]-[2], which considered multihop relaying in a single-cell setting. Considering an opportunistic hop-count routing algorithm, we study cellular sum capacity under different multiuser scheduling algorithms such as MaxCap, proportional fair, and round robin. We numerically investigate the competing interaction between multihop diversity and multiuser diversity, and discuss the areal diversity aspect as a byproduct of multihop relaying. Finally, we provide further practical design insights on cellular planning through our empirical results on interference statistics in multicellular multihop networks. I

Fluorescence emission and photooxidation studies with 5,6-and 6,7-benzocoumarins and a 5,6-benzochromone under direct and concentrated sun

WOS: 0001787825000214-Methyl-8-hydroxy-benzo(6,7)coumarin, 1,4-methyl-6-hydroxy-benzo(5,6)coumarin, II, and 2-methyl-6-hydroxy-benzo(5,6)chromone, III, have shown similar absorption and fluorescence emission spectra. Fluorescence emission quantum yields for I and III are found to be very low, phi(f) = 0.02, but 4-methyl-6-hydroxy-benzo(5,6)coumarin, II, has a eight-fold higher fluorescence quantum yield of the other two specie, in acetonitrile solution, of = 0.16. Quenching of anthracene fluorescence emission by 1, II and III are found to give k(q) values of 1.0 x 10(7)-1.2 x 10(9) M-1 s(-1). Benzo(5,6)coumarin, II, which gives the most intense fluorescence also presents the highest quenching rate, k(q) = 1.2 x 10(9) M-1 s(-1). Experimentally determined k(q) values are seen to correlate well with the free energy of electron transfer (DeltaG(ET)) which are calculated to be in the range of -8.0 to -9.4 kcal/mol, where benzo(5,6)coumarin, II, gives the lowest free energy of electron transfer DeltaG(ET) = -9.4 kcal/mol. These results indicate that I-III behave as electron acceptor moieties toward a condensed aromatic ring, anthracene. The Stokes shift values of 88-105 mm and broad fluorescence emission bands respect to absorption-excitation bands, indicates a molecular structure change in the excited states of I-III. Fluorescence lifetimes of 0.1-0.9 ns in I-III, singlet oxygen quantum yields of 0.15 and 0.40 for I and II, respectively, may be taken as evidence of singlet-triplet intersystem crossings. The photooxidation products of alpha-terpinene, sensitised by II, under direct and concentrated sun light conditions that are mainly p-cymene and ascaridole. In accordance with literature data on coumarin derivatives, benzocoumarins also seem to produce singlet oxygen and beside singlet oxygen, in addition super oxide anion radical production appear to be dominant especially under concentrated sun light. Under direct sun light conditions ascaridole is the major product. Some by-products of alpha-terpinene photooxidation are also determined at GC-MS analysis. Those by-products are assumed to be generated from ascaridole decomposition. (C) 2002 Elsevier Science B.V All rights reserved

Mineralogy and genesis of the Ni–Co lateritic regolith deposit of the Çaldağ area (Manisa, western Anatolia), Turkey

The Çaldağ Ni–Co deposit is characterized by a reddish brown oxide lateritic regolith, containing residual Ni deposit formed by the intense tropical weathering of peridotites. Nickel–Co ore is associated with transported ferricrete during the late Paleocene–middle Eocene, represented by colloform Fe oxides and residual lateritization during the Oligocene. The lateritic regoliths are developed over dunitic ultramafic rocks and consist mainly of smectite, berthierine, kaolinite, gypsum, pyrite, takovite, and pecoraite. These units were examined using polarized-light microscopy, X-ray diffraction, scanning and transmission electron microscopy, and geochemical methods. Mineralogical zonation from the base of the profile upwards has the following zones: ultramafic bedrocks, serpentinized ultramafic rocks (saprock), saprolite, carbonate- and sulfide-bearing zone, ferruginous saprolite zone, and silcrete. In addition, Fe oxides, smectite and opal-CT, and quartz increase towards the surface, whereas olivine, pyroxene, and serpentine decrease upwards in response to chemical weathering. Nickel–Co mineralization associated with Fe oxides and smectitic clays formed under wet and dry conditions, respectively, as a result of an increased Fe2O3 + Al2O3 + Ni + Co/MgO ratio. Field observations and mineralogical and geochemical analyses reveal that the smectite formed under basic conditions was controlled by multistage chemical weathering of ultramafic and volcanic rocks and by the concentrations of Si, Al, Fe, and Mg. Locally, concentrations of S in conjunction with Fe and Ca resulted in precipitation of goethite–hematite, gypsum, and pyrite in dissolution voids in association with smectite under acidic conditions that developed in a well-drained system. © 2018, Published by NRC Research Press.The study was supported by the Scientific and Technological Research Council of Turkey (TUBITAK). Mineralogy, micromorphology, and microchemistry studies of clay minerals were performed at Texas Tech University, Texas, USA. The authors are much indebted to Charles R.M. Butt (CSIRO Earth Science and Resource Engineering, Western Australia) and anonymous reviewers for their extremely careful and constructive reviews that improved the quality of the paper significantly. We are extremely grateful to Editor Ali Polat for his insightful editorial comments and suggestions. We are also grateful to Martin Wells (Mineral Resources, Kensington) and William L. Griffin (Macquarie University, Australia) for their critical and detailed reviews and suggestions on an early draft of the manuscript. We greatly thank Mehmet Yıldız and İ. Hakkı Karamanderesi for their help during the field studies. Mustafa Çiçek, Yasin Aydın, Okan Bektas¸, Tacit Külah, and Nergis Önalgil are also thanked for drafting assistance

Selective Cell Adhesion and Biosensing Applications of Bio-Active Block Copolymers Prepared by CuAAC/Thiol-ene Double Click Reactions

PubMed ID: 25974890N-Acetyl-l-cysteine (NAC)-capped poly(methyl methacrylate)-b-polycaprolactone block copolymer (PMMA-b-PCL-NAC) was prepared using the previously described one-pot photoinduced sequential CuAAC/thiol-ene double click procedure. PMMA-b-PCL-NAC had previously shown good applicability as a matrix for cell adhesion of cells from the Vero cell line (African green monkey kidney epithelial). Here, in this work, PMMA-b-PCL-NAC served as an excellent immobilization matrix for biomolecule conjugation. Covalent binding of RGD (R: arginine, G: glycine, and D: aspartic acid) peptide sequence onto the PMMA-b-PCL-NAC-coated surface was performed via EDC chemistry. RGD-modified PMMA-b-PCL-NAC (PMMA-b-PCL-NAC-RGD) as a non-toxic cell proliferation platform was used for selective "integrin ?vß3-mediated cell adhesion and biosensing studies. Both optical and electrochemical techniques were used to monitor the adhesion differences between "integrin ?vß3" receptor positive and negative cell lines on to the designed biofunctional surfaces. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim