魚貝類の薬物代謝酵素活性を指標とする水域汚染の判定

第1章 ヒブナ,クルマエビ,アサリおよびラットの各肝臓における薬物代謝酵素活性 第2章 コイ,ヒブナ,ニジマス,ティラピア,マダイおよびブリの肝臓,腎臓および鰓における薬物代謝酵素活性の比較 第3章 アサリ中腸腺の硫酸抱合酵素活性とフェノール化合物によるその誘導 第4章 コイ肝膵臓薬物代謝酵素活性と環境汚染物質によるその誘導 第5章 魚貝類の薬物代謝酵素活性を指標とする水域汚染の判定法Made available in DSpace on 2012-06-28T07:01:24Z (GMT). No. of bitstreams: 2 oshima1.pdf: 8711015 bytes, checksum: afc4f138bd4639297a6e5ec61ed17c9e (MD5) oshima2.pdf: 11136442 bytes, checksum: 12e60230599aa131f33253d452c2f145 (MD5) Previous issue date: 1992-02-26主1-参

Full thickness macular hole case after intravitreal aflibercept treatment

BACKGROUND: The pathogenesis of macular hole formation is widely accepted as a tractional force at the vitreo-retinal interface in fovea. We report a case of macular hole after intravitreous aflibercept injection for age-related macular degeneration (AMD) associated with contraction of the retinal pigment epithelium (RPE) at the edge of a fibrovascular pigment epithelial detachment (PED). CASE PRESENTATION: A 94-year old man with neovascular AMD affecting his left eye accompanied by a fibrovascular PED was examined for severe vision loss. Although RPE tear in his left eye was identified before the first aflibercept intravitreous injection performed in order to treat neovascular AMD, he received three aflibercept injections as induction treatment. After induction treatment, a full thickness macular hole was identified associated with the contracted rolled RPE edge beneath the retina. CONCLUSION: Macular hole is commonly formed associated with tangential vitreous traction. Current report suggests that rapid contraction of the RPE underneath the retina can be one of the causes of a macular hole, and one of the side effects of anti-VEGF therapy for neovascular AMD

Influence of the step number of the approach run on the jumping kinematics in volleyball spike jumps

Topics in Exercise Science and Kinesiology Volume 4: Issue 1, Article 15, 2023. In volleyball, the approach run serves as a strategy to execute a spike from an elevated striking position. Nevertheless, the influence of the step number of the approach run on the jumping kinematics in spike jumps is unclear. Therefore, this investigation aims to clarify the impact of varying step numbers within the approach run on jumping kinematics. Seven female volleyball athletes were tasked with executing spike jumps, employing 2 and 3-step approach runs. These trials were recorded using high-speed cameras and digitized, and then the kinematics of the 2 and 3-step trials were compared. The findings of this study unveiled that, in the 3-step trial with higher horizontal velocity, the center of gravity was upheld at an elevated level, thereby curtailing the vertical displacement of the center of gravity from the last step before the takeoff to the takeoff. Within the 2-step trial, a notable deceleration of horizontal velocity in the first half of the takeoff was virtually absent. However, the 3-step trial with higher horizontal velocity entailed more flexion of the dominant knee joint to decelerate the horizontal velocity during the first half. Furthermore, the 3-step trial entails a swifter extension of the hip, knee, and ankle joints of the non-dominant leg. This accelerated extension likely contributes to an augmented vertical velocity at the foot release of the takeoff

Electronic Structure of the Novel Filled Skutterudite PrPt₄Ge₁₂ Superconductor

We have performed soft x-ray photoemission spectroscopy (SXPES) and resonant photoemission spectroscopy (RPES) of the filled skutterudite superconductor PrPt4Ge12 in order to study the electronic structure of valence band and the character of Pr 4f. SXPES of PrPt4Ge12 measured with 1200 eV photon energy, where spectral contribution of Pr 4f is negligible, was found nearly identical with that of LaPt4Ge12, indicating similarity of Pt–Ge derived electronic states of the two compounds. Good correspondence with band calculations allows us to ascribe the dominant Ge 4p character of the density of states at the Fermi level (EF). Pr 3d → 4f RPES shows that, although Pr 4f electrons in PrPt4Ge12 are not as strongly hybridized with conduction electrons near EF as in PrFe4P12, there are finite Pr 4f contribution to the states near EF in PrPt4Ge12. These PES results give the information of fundamental electronic structure for understanding the physical properties of the novel filled skutterudite superconductor PrPt4Ge12