638 research outputs found
Exploring the impact of external shading system on cognitive task performance, alertness and visual comfort in a daylit workplace environment
The authors examined the effect of external shading system on cognitive performance, alertness and visual comfort of visual display terminal (VDT) users under two realistic office lighting settings in this study. Daylight was the source of illumination being considered as the most significant and preferred one. A total of 26 participants performed visual and cognitive demanding tasks as well as providing subjective alertness, performance and visual evaluations in a full-scale mock-up VDT workstation. Two trials (with and without shading system) were executed during one experimental session. Results revealed that the use of a shading system improves the performance of a user on colour-naming task requiring sustained attention, while no differential effects were observed on tasks involving other cognitive skills such as search velocity and vigilance. Within-subject performance differences were more pronounced during morning hours. Higher performance was reported in some cognitive tests when the subjective sensation of visual discomfort was lower
A short history of fuzzy, intuitionistic fuzzy, neutrosophic and plithogenic sets
Recently, research on uncertainty modeling is progressing rapidly and many essential and breakthrough stud ies have already been done. There are various ways such as fuzzy, intuitionistic and neutrosophic sets to handle these uncertainties. Although these concepts can handle incomplete information in various real-world issues, they cannot address all types of uncertainty such as indeterminate and inconsistent information. Also, plithogenic sets as a generalization of crisp, fuzzy, intuitionistic fuzzy, and neutrosophic sets, which is a set whose elements are characterized by many attributes’ values. In this paper, our aim is to demonstrate and review the history of fuzzy, intuitionistic and neutrosophic sets. For this purpose, we divided the paper as: section 1. History of Fuzzy Sets, section 2. History of Intuitionistic Fuzzy Sets and section 3. History of Neutrosophic Theories and Applications, section 4. History of Plithogenic Sets
Коррекция состояния иммунной системы крыс с адъювантным артритом введением липидной фракции плаценты
Введення ліпідної фракції плаценти, отриманої методом кріогенного молекулярного фракціонування, на фоні розвитку ад’ювантного артриту оказує корегуючий вплив у відношенні як вмісту, так і функціональної активності регуляторних Т-клітин регіональних лімфовузлів, що призводить до зниження інтенсивності клінічних ознак захворювання.Injection of placental lipid fraction obtained by cryogenic molecular fractionation method on the background of adjuvant arthritis development has a correcting influence in relation to both content and functional activity of regulatory T-cells of regional lymph nodes which leads to a decrease in intensity of clinical signs of the disease
3D segmentation of intervertebral discs: from concept to the fabrication of patient-specific scaffolds
Aim: To develop a methodology for producing patient-specific scaffolds that mimic the annulus fibrosus (AF) of the human intervertebral disc (IVD) by means of combining magnetic resonance imaging (MRI) and 3D bioprinting. Methods: In order to obtain the AF 3D model from patientâ s volumetric MRI dataset, the RheumaSCORE segmentation software was used. Polycaprolactone scaffolds with three different internal architectures were fabricated by 3D bioprinting, and characterized by micro-computed tomography.
Results: The demonstrated methodology of a geometry reconstruction pipeline enabled to successfully obtain an accurate AF model and 3D print patient-specific scaffolds with different internal architectures.
Conclusion: The results guide us towards patient-specific IVD tissue engineering as demonstrated a way of manufacturing personalized scaffolds using patient's MRI data.The authors would like to acknowledge the financial support provided by the Portuguese Foundation for Science and Technology (FCT) through the project EPIDisc (UTAPEXPL/BBB-ECT/0050/2014),
funded in the Framework of the ‘International Collaboratory for Emerging Technologies, CoLab’, UT
justin|Portugal Program. FCT is also acknowledged for the PhD scholarship attributed to IF Cengiz (SFRH/
BD/99555/2014) and the financial support provided to J Silva-Correia (SFRH/BPD/100590/2014 and IF/00115/2015).
JM Oliveira also thanks the FCT for the funds provided under the program Investigador FCT (IF/00423/2012 and IF/01285/2015). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.info:eu-repo/semantics/publishedVersio
Compton Scattering from the Deuteron and Extracted Neutron Polarizabilities
Differential cross sections for Compton scattering from the deuteron were
measured at MAX-lab for incident photon energies of 55 MeV and 66 MeV at
nominal laboratory angles of , , and . Tagged
photons were scattered from liquid deuterium and detected in three NaI
spectrometers. By comparing the data with theoretical calculations in the
framework of a one-boson-exchange potential model, the sum and difference of
the isospin-averaged nucleon polarizabilities, and (in units of fm),
have been determined. By combining the latter with the global-averaged value
for and using the predictions of the Baldin sum rule for
the sum of the nucleon polarizabilities, we have obtained values for the
neutron electric and magnetic polarizabilities of (total) (model) and (total) (model), respectively.Comment: 4 pages, 2 figures, revtex. The text is substantially revised. The
cross sections are slightly different due to improvements in the analysi
Diagnosis of diffuse idiopathic skeletal hyperostosis with chest computed tomography:inter-observer agreement
To evaluate and improve the interobserver agreement for the CT-based diagnosis of diffuse idiopathic skeletal hyperostosis (DISH). Six hundred participants of the CT arm of a lung cancer screening trial were randomly divided into two groups. The first 300 CTs were scored by five observers for the presence of DISH based on the original Resnick criteria for radiographs. After analysis of the data a consensus meeting was organised and the criteria were slightly modified regarding the definition of 'contiguous', the definition of 'flowing ossifications' and the viewing plane and window level. Subsequently, the second set of 300 CTs was scored by the same observers. kappa >= 0.61 was considered good agreement. The 600 male participants were on average 63.5 (SD 5.3) years old and had smoked on average 38.0 pack-years. In the first round kappa values ranged from 0.32 to 0.74 and 7 out of 10 values were below 0.61. After the consensus meeting the interobserver agreement ranged from 0.51 to 0.86 and 3 out of 10 values were below 0.61. The agreement improved significantly. This is the first study that reports interobserver agreement for the diagnosis of DISH on chest CT, showing mostly good agreement for modified Resnick criteria. . DISH is diagnosed on fluoroscopic and radiographic examinations using Resnick criteria . Evaluation of DISH on chest CT was modestly reproducible with the Resnick criteria . A consensus meeting and Resnick criteria modification improved inter-rater reliability for DISH . Reproducible CT criteria for DISH aids research into this poorly understood entity
Prospective study of avian influenza transmission to humans in egypt
<p>Abstract</p> <p>Background</p> <p>The highly pathogenic avian influenza (HPAI) H5N1 virus remains a public health threat and continues to cause outbreaks among poultry as well as human infections. Since its appearance, the virus has spread to numerous geographic areas and is now considered endemic in Egypt and other countries. Most studies on human H5N1 cases were conducted to investigate outbreak situations and were not designed to address fundamental questions about the epidemiology of human infection with H5N1 viruses. Our objective for this study is to answer these questions by estimating the prevalence and incidence rates of human cases and determine associated risk and protective factors in areas where H5N1 viruses are endemic.</p> <p>Methods/Design</p> <p>We designed a 3-year prospective cohort study of 1000 individuals of various exposure levels to poultry in Egypt. At onset, we will collect sera to estimate baseline antibody titers against AI viruses H4-H16. Two follow-up visits are scheduled at 1-year intervals following initial enrollment. At follow-up, we will also collect sera to measure changes in antibody titers over time. Thus, annual prevalence rates as well as incidence rates of infection will be calculated. At each visit, exposure and other data will be collected using a specifically tailored questionnaire. This data will be used to measure risk and protective factors associated with infection. Subjects will be asked to contact the study team any time they have influenza-like illness (ILI). In this case, the study team will verify infection by rapid influenza A test and obtain swabs from the subject's contacts to isolate and characterize viruses causing acute infection.</p> <p>Discussion</p> <p>Epidemiologic studies at the influenza human-animal interface are rare, hence many questions concerning transmission, severity, and extent of infection at the population level remain unanswered. We believe that our study will help tackle and clarify some of these issues.</p
Conducting a European multi-center trial: first experiences with the new EU Clinical Trials Directive from an academic perspective
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