1,115 research outputs found
Thermodynamics of lattice QCD with 2 sextet quarks on N_t=8 lattices
We continue our lattice simulations of QCD with 2 flavours of colour-sextet
quarks as a model for conformal or walking technicolor. A 2-loop perturbative
calculation of the -function which describes the evolution of this
theory's running coupling constant predicts that it has a second zero at a
finite coupling. This non-trivial zero would be an infrared stable fixed point,
in which case the theory with massless quarks would be a conformal field
theory. However, if the interaction between quarks and antiquarks becomes
strong enough that a chiral condensate forms before this IR fixed point is
reached, the theory is QCD-like with spontaneously broken chiral symmetry and
confinement. However, the presence of the nearby IR fixed point means that
there is a range of couplings for which the running coupling evolves very
slowly, i.e. it 'walks'. We are simulating the lattice version of this theory
with staggered quarks at finite temperature studying the changes in couplings
at the deconfinement and chiral-symmetry restoring transitions as the temporal
extent () of the lattice, measured in lattice units, is increased. Our
earlier results on lattices with show both transitions move to weaker
couplings as increases consistent with walking behaviour. In this paper
we extend these calculations to . Although both transition again move to
weaker couplings the change in the coupling at the chiral transition from
to is appreciably smaller than that from to .
This indicates that at we are seeing strong coupling effects and that
we will need results from to determine if the chiral-transition
coupling approaches zero as , as needed for the theory
to walk.Comment: 21 pages Latex(Revtex4) source with 4 postscript figures. v2: added 1
reference. V3: version accepted for publication, section 3 restructured and
interpretation clarified. Section 4 future plans for zero temperature
simulations clarifie
Experimental conversion of a defensin into a neurotoxin: Implications for origin of toxic function
Scorpion K+ channel toxins and insect defensins share a conserved three-dimensional structure and related biological activities (defense against competitors or invasive microbes by disrupting their membrane functions), which provides an ideal system to study how functional evolution occurs in a conserved structural scaffold. Using an experimental approach, we show that the deletion of a small loop of a parasitoid venom defensin possessing the “scorpion toxin signature” (STS) can remove steric hindrance of peptide-channel interactions and result in a neurotoxin selectively inhibiting K+ channels with high affinities. This insect defensin-derived toxin adopts a hallmark scorpion toxin fold with a common cysteine-stabilized α-helical and β-sheet motif, as determined by nuclear magnetic resonance analysis. Mutations of two key residues located in STS completely diminish or significantly decrease the affinity of the toxin on the channels, demonstrating that this toxin binds to K+ channels in the same manner as scorpion toxins. Taken together, these results provide new structural and functional evidence supporting the predictability of toxin evolution. The experimental strategy is the first employed to establish an evolutionary relationship of two distantly related protein families
Analysis of mechanism of sand deposition inside a fishing port using BG model
A large amount of sand deposited in the wave-shelter zone of Ohtsu fishing port located in northern Ibaraki Prefecture, Japan, resulting in a difficulty in navigation at the pot entrance. The BG model (a three-dimensional model for predicting beach changes based on Bagnold's concept) ws used to solve this problem. Measures against sand deposition inside the port were investigated and the most appropriate measure found for preventing sand deposition was the extension of a jetty by 100 m at the tip of the west breakwater. The applicability of the BG model to such prediction was confirmed
Generation of Cosmological Seed Magnetic Fields from Inflation with Cutoff
Inflation has the potential to seed the galactic magnetic fields observed
today. However, there is an obstacle to the amplification of the quantum
fluctuations of the electromagnetic field during inflation: namely the
conformal invariance of electromagnetic theory on a conformally flat underlying
geometry. As the existence of a preferred minimal length breaks the conformal
invariance of the background geometry, it is plausible that this effect could
generate some electromagnetic field amplification. We show that this scenario
is equivalent to endowing the photon with a large negative mass during
inflation. This effective mass is negligibly small in a radiation and matter
dominated universe. Depending on the value of the free parameter of the theory,
we show that the seed required by the dynamo mechanism can be generated. We
also show that this mechanism can produce the requisite galactic magnetic field
without resorting to a dynamo mechanism.Comment: Latex, 16 pages, 2 figures, 4 references added, minor corrections;
v4: more references added, boundary term written in a covariant form,
discussion regarding other gauge fields added, submitted to PRD; v5: matched
with the published versio
Low-Frequency Quantum Sensing
低周波信号の新規高感度量子センシング手法を開発 --NV量子センサを用いた核磁気共鳴(NMR)世界最小線幅を実証--. 京都大学プレスリリース. 2022-11-01.Exquisite sensitivities are a prominent advantage of quantum sensors. Ramsey sequences allow precise measurement of direct current fields, while Hahn-echo-like sequences measure alternating current fields. However, the latter are restrained for use with high-frequency fields (above approximately 1kHz) due to finite coherence times, leaving less-sensitive noncoherent methods for the low-frequency range. In this paper, we propose to bridge the gap with a fitting-based algorithm with a frequency-independent sensitivity to coherently measure low-frequency fields. As the algorithm benefits from coherence-based measurements, its demonstration with a single nitrogen-vacancy center gives a sensitivity of 9.4nT Hz⁻⁰.⁵ for frequencies below about 0.6kHz down to near-constant fields. To inspect the potential in various scenarios, we apply the algorithm at a background field of tens of nTs, and we measure low-frequency signals via synchronization
Severe myoclonic epilepsy in infancy: evolution of seizures
Changes in seizure type of severe myoclonic epilepsy (SME) in infancy were reviewed retrospectively in 14 patients (11 males and 3 females) who were followed-up to the age of 7 years or more. The observation period ranged from 5 to 16 years with a mean of 10 years. During the follow-up, three or four types of seizures were seen per patient, but the pattern of appearance and disappearance of each seizure type varied considerably among the patients. Tonic-clonic convulsion, either generalized or unilateral, was seen most consistently through the entire course, and it continued to the end of follow-up in 11 patients (79%). On the contrary, myoclonic seizure, complex partial seizure, and atypical absence often disappeared and reappeared repeatedly during the course. In SME, seizure symptoms varied widely among patients in comparison with other neurological symptoms, and the most consistent core seizure type was tonic-clonic convulsions
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