62 research outputs found
Effects of Fermi surface and superconducting gap structure in the field-rotational experiments: A possible explanation of the cusp-like singularity in YNiBC
We have studied the field-orientational dependence of zero-energy density of
states (FODOS) for a series of systems with different Fermi surface and
superconducting gap structures. Instead of phenomenological Doppler-shift
method, we use an approximate analytical solution of Eilenberger equation
together with self-consistent determination of order parameter and a
variational treatment of vortex lattice. First, we compare zero-energy density
of states (ZEDOS) when a magnetic field is applied in the nodal direction
() and in the antinodal direction (), by taking
account of the field-angle dependence of order parameter. As a result, we found
that there exists a crossover magnetic field so that for for , consistent with our previous analyses. Next, we showed that and the
shape of FODOS are determined by contribution from the small part of Fermi
surface where Fermi velocity is parallel to field-rotational plane. In
particular, we found that is lowered and FODOS has broader minima, when a
superconducting gap has point nodes, in contrast to the result of the
Doppler-shift method. We also studied the effects of in-plane anisotropy of
Fermi surface. We found that in-plane anisotropy of quasi-two dimensional Fermi
surface sometimes becomes larger than the effects of Doppler-shift and can
destroy the Doppler-shift predominant region. In particular, this tendency is
strong in a multi-band system where superconducting coherence lengths are
isotropic. Finally, we addressed the problem of cusp-like singularity in
YNiBC and present a possible explanation of this phenomenon.Comment: 13pages, 23figure
Fixation of Compressed Wood Using Melamine-Formaldehyde Resin
Methods to maximize wood hardness and dimensional stability include various combinations of compression, heating, and chemical treatment. In this study, wood was treated with increasing concentrations of a low molecular weight, water-soluble melamine-formaldehyde resin solution (mol wt 380) and compressed while heated. This method achieved a maximum bulking efficiency of 5% and an antishrink efficiency of 45%, showing that the chemical had not completely penetrated the cell wall. Once the wood was treated, its ability to retain the compressed state was tested by immersing wood specimens in water at different temperatures. Specimens treated with an 8% resin solution retained almost complete fixation when soaked in room-temperature water, while those treated with a 25% solution retained fixation in boiling water. Moreover, a 25% solution of resin and a compression of 54% increased hardness from 0.48 to 0.72 MPa
マウス骨髄造血前駆細胞由来の異なる樹状細胞サブセットでのケモカインによる走化遊走活性と腫瘍増殖因子によるその活性調節に関する研究
取得学位 : 博士(医学), 学位授与番号 : 医博甲第1427号,学位授与年月日:平成12年4月30日,学位授与年:200
Severe Alport syndrome in a young woman caused by a t(X;1)(q22.3;p36.32) balanced translocation
ADAMTS-1: A metalloproteinase-disintegrin essential for normal growth, fertility, and organ morphology and function
金沢大学医薬保健研究域医学系A disintegrin and metalloproteinase (ADAM) represents a protein family possessing both metalloproteinase and disintegrin domains. ADAMTS-1, an ADAM family member cloned from cachexigenic colon adenocarcinoma, is unusual in that it contains thrombospondin type I motifs and anchors to the extracellular matrix. To elucidate the biological role of ADAMTS-1, we developed ADAMTS-1-null mice by gene targeting. Targeted disruption of the mouse ADAMTS-1 gene resulted in growth retardation with adipose tissue malformation. Impaired female fertilization accompanied by histological changes in the uterus and ovaries also resulted. Furthermore, ADAMTS-1(-/-) mice demonstrated enlarged renal calices with fibrotic changes from the ureteropelvic junction through the ureter, and abnormal adrenal medullary architecture without capillary formation. ADAMTS-1 thus appears necessary for normal growth, fertility, and organ morphology and function. Moreover, the resemblance of the renal phenotype to human ureteropelvic junction obstruction may provide a clue to the pathogenesis of this common congenital disease
Coulomb breakup reactions of 93,94 Zr in inverse kinematics
Coulomb breakup reactions of 93,94 Zr have been studied in inverse kinematics at incident beam energies of about 200 MeV/nucleon in order to evaluate neutron capture reaction methods. The 93 Zr(n,γ) 94 Zr reaction is particularly important as a candidate nuclear transmutation reaction for the long-lived fission product 93 Zr in nuclear power plants. One- and two-neutron removal cross sections on Pb and C targets were measured to deduce the inclusive Coulomb breakup cross sections, 375 ± 29 (stat.) ± 30 (syst.) and 403 ± 26 (stat.) ± 31 (syst.) mb for 93 Zr and 94 Zr, respectively. The results are compared with estimates using the standard Lorentzian model and microscopic calculations. The results reveal a possible contribution of the pygmy dipole resonance or giant quadrupole resonance in the Coulomb breakup reactions of 94 Zr
The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force
「コロナ制圧タスクフォース」COVID-19患者由来の血液細胞における遺伝子発現の網羅的解析 --重症度に応じた遺伝子発現の変化には、ヒトゲノム配列の個人差が影響する--. 京都大学プレスリリース. 2022-08-23.Coronavirus disease 2019 (COVID-19) is a recently-emerged infectious disease that has caused millions of deaths, where comprehensive understanding of disease mechanisms is still unestablished. In particular, studies of gene expression dynamics and regulation landscape in COVID-19 infected individuals are limited. Here, we report on a thorough analysis of whole blood RNA-seq data from 465 genotyped samples from the Japan COVID-19 Task Force, including 359 severe and 106 non-severe COVID-19 cases. We discover 1169 putative causal expression quantitative trait loci (eQTLs) including 34 possible colocalizations with biobank fine-mapping results of hematopoietic traits in a Japanese population, 1549 putative causal splice QTLs (sQTLs; e.g. two independent sQTLs at TOR1AIP1), as well as biologically interpretable trans-eQTL examples (e.g., REST and STING1), all fine-mapped at single variant resolution. We perform differential gene expression analysis to elucidate 198 genes with increased expression in severe COVID-19 cases and enriched for innate immune-related functions. Finally, we evaluate the limited but non-zero effect of COVID-19 phenotype on eQTL discovery, and highlight the presence of COVID-19 severity-interaction eQTLs (ieQTLs; e.g., CLEC4C and MYBL2). Our study provides a comprehensive catalog of whole blood regulatory variants in Japanese, as well as a reference for transcriptional landscapes in response to COVID-19 infection
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