A population-based survey of obstetric practices among rural women in the Bizana district, Transkei

No Abstract

A case of granulomatous rosacea

A 49-year-old housewife had complained of an itchy facial rash for four years. She denied using steroid creams and skin lighteners. On examination, dark grey papules were found on her face, with some coalescing into plaques (see Figures 1 and 2). A skin biopsy revealed many perifollicular non-caseating granulomas (see Figure 3). Periodic Acid-Schiff stains for fungi, Ziehl-Neelson stains for M tuberculosis, and Fite-Ferraco stains for M leprae were negative

The Vengeful Victim? Assessing the Attitudes of Victims Participating in Restorative Youth Conferencing

Considers the findings of research into the youth conferencing system in Northern Ireland which assessed the validity of the view that victim participation in sentencing decisions would lead to higher sentences with a greater retributive element. Outlines the victims' reasons for participating in the conference, and their descriptions of their experiences. Analyses the elements of the conference plans negotiated with the victims' participation

Tablet computers for recording tuberculosis data at a community health centre in King Sabata Dalindyebo Local Municipality, Eastern Cape: a proof of concept report

Background: Data at primary healthcare (PHC) clinics are handwritten in registers by nurses for submission to the District Health Information System (DHIS). Compared to pen and paper, data capture, using handheld computers, has fewer errors, is more efficient and is readily accepted by users. This study describes the process of developing a tablet computer programme to capture data, and explores nurses’ experiences of using tablets at a community health centre.Method: OpenDataKit® was used to design XForms for touchscreen entry. Data for tuberculosis screening were captured by nurses on Android® 9.7-inch tablets over a week. Their experience was explored by means of a focus group interview.Results: Data were recorded for 24 patients and seamlessly transferred for analysis. Nurses thought that the tablets were easy to use and saved time. They would be happy to use tablets in preference to pen and paper. They  expressed a desire to extend the use of tablets to other areas of their work.Conclusion: Tablet computers were readily accepted by the nurses. They are a feasible alternative to pen and paper for recording data at point of care. This tablet-based system could be used to transfer PHC data directly to the DHIS.Keywords: analysis, clinic data, computers, Eastern Cape, primary health care, tablet, tuberculosis dat

Taming tosyl azide: the development of a scalable continuous diazo transfer process

Heat and shock sensitive tosyl azide was generated and used on demand in a telescoped diazo transfer process. Small quantities of tosyl azide were accessed in a one pot batch procedure using shelf stable, readily available reagents. For large scale diazo transfer reactions tosyl azide was generated and used in a telescoped flow process, to mitigate the risks associated with handling potentially explosive reagents on scale. The in situ formed tosyl azide was used to rapidly perform diazo transfer to a range of acceptors, including β-ketoesters, β-ketoamides, malonate esters and β-ketosulfones. An effective in-line quench of sulfonyl azides was also developed, whereby a sacrificial acceptor molecule ensured complete consumption of any residual hazardous diazo transfer reagent. The telescoped diazo transfer process with in-line quenching was used to safely prepare over 21 g of an α-diazocarbonyl in >98% purity without any column chromatography

Inter-relationships between composition, physicochemical properties and functionality of lecithin ingredients

Background: Lecithin is widely used as an ingredient in the food industry due to its diverse functionality, mainly attributed to phospholipids (PL), the principal constituents. However, a systematic understanding of the functional properties of lecithin ingredients is missing in the literature. Scope and approach: This review outlines recent developments in lecithin from botanical origin and reviews the complex inter-relationships between physicochemical properties of PL in lecithin and selected techno-functional properties in micelles, liposomes and oil-in-water emulsions. Key findings and conclusions: Attributed to their polar phosphatide group and non-polar fatty acids, PL have specific molecular geometries, dissociation constants and charge, which strongly influence their functional properties in micelles, liposomes and oil-in-water emulsions. The PL profile and extrinsic factors (e.g., water, oil, hexane) influence the formation of micelles during separation of lecithin from oil using membrane filtration. In liposomes, PL profile and the presence of surface modifiers (i.e., sterols) affect the particle size and encapsulation efficiency. In emulsion systems, PL and their interaction with minerals and other functional ingredients (e.g., proteins), influence the particle size and physical stability of the oil droplets. This work provides an integrated review of the links between the composition and physicochemical properties of PL, and in turn, scientifically underpins the links between physicochemical and functional properties of lecithin

Haemophilia care in Europe:a survey of 19 countries

In 2009, a questionnaire was circulated to 19 national haemophilia patient organizations in Europe affiliated to the European Haemophilia Consortium (EHC) and the World Federation of Hemophilia (WFH) to seek information about the organization of haemophilia care and treatment available at a national level. The responses received highlighted differences in the level of care despite the recent promulgation of consensus guidelines designed to standardize the care of haemophilia throughout the continent of Europe. There was a wide range in factor VIII consumption with usage ranging from 0.38 IU per capita in Romania to 8.7 IU per capita in Sweden (median: 3.6 IU per capita). Despite the specific inclusion of coagulation factor concentrate in the WHO list of essential medications, cryoprecipitate is still used in some eastern European countrie