65 research outputs found
A Study of Eastern Culture from the Philosophical Perspective
In the world philosophies the Eastern has investigated everything in their aesthetic component on the other hand the Western has investigated these things in their theoretic component. The main objective of this paper is intended to study on Eastern culture from the philosophical Perspective. Most of the Easterners emphasized on man than on his natural world and one of the characteristics of Eastern culture is fundamentally religious in character. The research problem of this paper is âwhy the Easternersâ ways of thinking seems to emphasize on the human concern in aesthetic component?â The solution of this paper is that Easternerâs ways of thinking generally based on emotional sense than rational sense. Hence they place emphasis on knowledge by intuition and on contemplation of everything in their aesthetic immediacy. This research paper will contribute to promote understanding that people can put into practice reconciliation of the philosophical perspective of the East and the West in order to achieve a comprehensive integration. As a consequence we enable to establish mutual understanding and good communication among different cultures
Virulence factors and genetic characteristics of methicillin-resistant and - susceptible staphylococcus aureus isolates in Myanmar
Staphylococcus aureus produces virulence factors, including various exotoxins and adhesins, which are associated with a variety of symptoms caused by its infections. In the present study, the prevalence of these virulence factors was analyzed for 23 S. aureus strains isolated from wound infections in hospitals, nasal swabs, or vomit from patients and cooks in a food poisoning case and from healthy adults in Yangon, Myanmar. Among these strains, five were methicillin-resistant S. aureus (MRSA) derived from pus (four strains, SCCmec III, ST239) and a healthy adult (one strain, SCCmec-IVa, ST5). The Panton-Valentine leukocidine (PVL) gene was detected in five methicillin-susceptible S. aureus (MSSA) clinical strains belonging to ST121 (CC121). The MRSA clinical strains had only a few or no staphylococcal enterotoxin (SE) genes, whereas PVL-positive MSSA and an MRSA strain from a healthy adult possessed an enterotoxin gene cluster (seg, sei, sem, sen, seo, and selu). Strains from the food poisoning case had either SE genes or only etd and edin-B. Adhesin genes, which are associated with binding to fibronectin, fibrinogen, and elastin, were detected in all the MRSA and most of the MSSA strains examined. However, the bone sialoprotein-binding protein gene (bbp) and the variant form of the elastin-binding protein gene (ebpS-v) with an internal 180ââŹâ°bp deletion were identified only in the MSSA strains harboring the PVL gene. These findings suggest that those genetic traits are characteristic of PVL-positive ST121 S. aureus strains in Myanmar
Remodeling in the Prefrontal Cortex of a Brain-related to Higher Executive Functions in Adolescence: Its effects on Behavior
Adolescence is a critical stage of the developmental trajectory, where a childâs transition to independent living
may result in lead healthy or unhealthy styles. During this period, it is easier to mend an individual as a healthy
adult; at the same time, misguided children may enter into risky behaviors. The aim of the study to get an insight
into changing brains of adolescents and their behavioral outcomes. The current review search engine proceeds
with reviewing the literature in the past through electronic databases such as PubMed, Medline, and Scopus
databases using keywords such as adolescent stage, the brain of teenagers, risk behaviors, reduction in gray
matter in the prefrontal cortex. The current study reviewed and analyzed 20 articles. The reviewed articles would
increase the awareness and insights regarding brain changes and their behavioral outcomes. This insightful
informationâs drawn out of the study may help professionals and parents who intervene in the adolescentâs
problem behaviors
ACUTE FATTY LIVER IN PREGNANCY
Acute fatty liver of pregnancy (AFLP) is an obstetric emergency and life threatening condition of the pregnancy. It affects during last trimester of pregnancy and occasionally occurs in postpartum period. It is presented with malaise, nausea, vomiting, and epigastric pain followed by jaundice. Laboratory tests usually derange liver and renal functions with coagulopathy. The incidence of AFLP is approximately 1 in 15,000 pregnancies. We reported the case of a 34-year-old patient, with multiple pregnancy at 35 weeks of gestation presented with dizziness, headache and dyspepsia aggravated by lying down and noted jaundice during operation. She had postpartum haemorrhage after the operation due to coagulopathy and her laboratory investigations findings favoured to diagnosis as AFLP and treated with supportive management at intensive care unit (ICU). Therefore obstetrician must be aware of one of this hepatic problem in pregnant women at latetrimester
Preventive chemotherapy reverses covert, lymphatic associated tissue change in young people with lymphatic filariasis in Myanmar
Objectives
This longitudinal comparative study investigated the effect of preventive chemotherapy
(PC) on covert tissue changes associated with lymphatic filariasis (LF) among young people living in
an LF-endemic area in Myanmar.
Methods
Tissue compressibility and extracellular free fluid in the lower limbs of people aged 10â
21 years were measured using indurometry and bioimpedance spectroscopy (BIS). Baseline measures
were taken in October 2014, annual mass drug administration (MDA) of PC was delivered in
December, and in March 2015 further PC was offered to LF-positive cases who had missed MDA.
Follow-up measures were taken in February and June 2015.
Results
A total of 50 antigenâpositive cases and 46 antigenânegative controls were included. Selfâreported PC consumption was 60.1% during 2014 MDA and 66.2% overall. At second followâup, 24 of 34 cases and 27 of 43 controls had consumed PC. Significant and clinically relevant betweenâgroup differences at baseline were not found postâPC. Bayesian linear mixed models showed a significant change in indurometer scores at both calves for antigenâpositive cases who consumed any PC (dominant calf: â0.30 [95% CI â0.52, â0.07], P < 0.05 and nonâdominant calf: â0.35 [95% CI â0.58, â0.12], P < 0.01). Changes in antigenânegative participants or those not consuming PC were not significant.
Conclusion
This study is the first attempt to use simple fieldâfriendly tools to track fluid and tissue changes after treatment of asymptomatic people infected with LF. Results suggested that PC alone is sufficient to reverse covert lymphatic disturbance. Longer followâup of larger cohorts is required to confirm these improvements and whether they persist over time. These findings should prompt increased efforts to overcome low PC coverage, which misses many infected young people, particularly males, who are unaware of their infection status, unmotivated to take PC and at risk of developing lymphoedema. Indurometry and BIS should be considered in assessment of lymphatic filariasisârelated lymphedema
Risk factors for lymphatic filariasis and mass drug administration nonâparticipation in Mandalay Region, Myanmar
Background
Myanmar commenced a lymphatic filariasis (LF) elimination programme in 2000. Whilst the country has made considerable progress since then, a number of districts have demonstrated persistent transmission after many rounds of mass drug administration (MDA). The causes of unsuccessful MDA have been examined elsewhere; however, there remains little information on the factors that contribute in Myanmar.
Methods
We conducted an analysis of factors associated with persistent infection, LF-related hydrocoele and MDA participation in an area with ongoing transmission in 2015. A cross-sectional household survey was undertaken in 24 villages across four townships of Mandalay Region. Participants were screened for circulating filarial antigen (CFA) using immunochromatographic tests and, if positive, for microfilaria by night-time thick blood slide. Individuals 15 year and older were assessed for filariasis morbidity (lymphoedema and, if male, hydrocoele) by ultrasound-assisted clinical examination. A pre-coded questionnaire was used to assess risk factors for LF and for non-participation (never taking MDA). Significant variables identified in univariate analyses were included in separate step-wise multivariate logistic regressions for each outcome.
Results
After adjustment for covariates and survey design, being CFA positive was significantly associated with age [odds ratio (OR) 1.03, 95% CI 1.01â1.06), per year], male gender (OR 3.14, 1.27â7.76), elevation (OR 0.96, 0.94â0.99, per metre) and the density of people per household room (OR 1.59, 1.31â1.92). LF-related hydrocoele was associated with age (OR 1.06, 1.03â1.09, per year) and residing in Amarapura Township (OR 8.93, 1.37â58.32). Never taking MDA was associated with male gender [OR 6.89 (2.13â22.28)] and age, particularly in females, with a significant interaction term. Overall, compared to those aged 30â44 years, the proportion never taking MDA was higher in all age groups (OR highest in those â60 years, ranging from 3.37 to 12.82). Never taking MDA was also associated with residing in Amarapura township (OR 2.48, 1.15â5.31), moving to oneâs current village from another (OR 2.62, 1.12â6.11) and ever having declined medication (OR 11.82, 4.25â32.91). Decreased likelihood of never taking MDA was associated with a higher proportion of household members being present during the last MDA round (OR 0.16, 0.03â0.74) and the number visits by the MDA programme (OR 0.69, 0.48â1.00).
Conclusions
These results contribute to the understanding of LF and MDA participation-related risk factors and will assist Myanmar to improve its elimination and morbidity management programmes
Ovarian teratoma-associated anti-NMDAR encephalitis in a 12-year-old girl
aspartate receptor (anti-NMDAR) is one of the most commonautoimmune encephalitis syndromes and it is a serious andpotentially fatal pathology that occurs in young women. Thiscase report describes of a pediatric patient with anti-NMDARencephalitis. A-12-year-old girl presented with abnormalbehavior for one week came to Emergency Department ofSarawak General Hospital, Malaysia. She had psychoticspectrum symptoms including suicidal tendency. She wasdiagnosed with anti-NMDAR encephalitis as positiveantibody was seen in her cerebrospinal fluid. She wastreated with Injection Immunoglobulin. She turned out tohave teratoma which was successfully removed later. Herprogress was remarkable after the surgery with theImmunoglobulin. A multi-disciplinary team involving apsychiatrist, neurologist and gynaecologist liaised withintensivist to successfully manage the case and achieve thegood outcome
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