The Simplest Model of the Turning Movement of a Car with its Possible Sideslip

The simplest model of the turning movement of a car with its possiple sideslip is considered. To this end, a nonholonomic problem with nonretaining constraints is solved. The four possible types of the car motion are studied

Effects of α-amylase, endo-xylanase and exoprotease combination on dough properties and bread quality

Received: January 31st, 2021 ; Accepted: May 2nd, 2021 ; Published: May 6th, 2021 ; Correspondence: [email protected] enzymes composition is an actual alternative to chemicals to improve functional properties of flours and to generate changes in the structure of the dough and bread quality. The objective of this study was to analyze the individual and synergistic effects of enzymes preparation (α-amylase, endo-xylanase and exoprotease), newly produced in Russia, on dough properties and bread quality made from wheat flour with different amylolytic activity. Reofermentometric results revealed decreases in gas-forming capacity of dough by 10.0–13.9% when single α-amylase preparates were used. The α-amylase addition had significant effect on gas retention coefficient in flour possessed low amylolytic activity. The effect of endo-xylanase and exoprotease on hydration and amount of wheat gluten was established. The fractional composition of gluten proteins in the dough made with combination of endo-xylanase and exoprotease was established using Lowry method immediately after kneading and after fermentation. It was found that mainly water-soluble, alcohol-soluble and alkaline-soluble proteins were undergone by transformation. The bread with enzymes had a higher specific volume, porosity and aldehyde content and lower shape stability indicator than the control bread made without enzymes. Bread with enzymes was characterized by tenderer and not crumbly crumb with developed thin-walled uniform porosity compared to the control. The crusts were more brightly colored. The combined usage of α-amylase and endo-xylanase and exoprotease retarded bread staling during 5-day storage period. New enzyme composition may be a potentially strong candidate for future applications in the bread-making industry

Case of Hemorrhagic Vasculitis with Difficult Stream of 9 Years Old Boy

We are presenting a case of hemorrhagic vasculitis with difficult stream of 9 years old boy. Feature of this case is manifestation of the disease after quinsy with pronounced lymphoproliferative syndrome (enlargement of anterior and posterior cervical and submandibular lymph nodes up to 12-15 mm in diameter), which made it necessary to conduct a differential diagnosis with lymphoproliferative disorders. Thereby the biopsy of lymph node was made. Another feature was that with hemorrhagic rash on lower extremities extensive necrosis were developed, accompanied by severe pain and no analgesic effect. Later joined abdominal and renal syndromes, with development of cruel nephritis. The therapy allowed to achieve clinical remission, however the urinary syndrome retained for long. After correction of the therapy (sandimmun) there were marked rapid positive changes

The Impact of Methadone Maintenance Therapy on Access to Regular Physician Care Regarding Hepatitis C Among People who Inject Drugs

Background & aims People who inject drugs (PWID) living with hepatitis C virus (HCV) infection often experience barriers to accessing HCV treatment and care. New, safer and more effective directacting antiviral-based therapies offer an opportunity to scale-up HCV-related services. Methadone maintenance therapy (MMT) programs have been shown to be effective in linking PWID to health and support services, largely in the context of HIV. The objective of the study was to examine the relationship between being enrolled in MMT and having access to regular physician care regarding HCV among HCV antibody-positive PWID in Vancouver, Canada

3-ARYL-[1,2,4]TRIAZOLO[4,3-c]QUINAZOLINE DERIVATIVES: SYNTHESIS AND MODIFICATIONS

This work was supported by the Ministry of Science and Higher Education of Russian Federation, State Contract no FEUZ-2020-0058 (Н687.42Б.223/20)

Working in (Slow) Progress: Socio-Environmental and Economic Dynamics in the Forestry Sector and the Contribution to Sustainable Development in Europe

Forest ecosystems are increasingly subject to disturbances, such as extreme (climate) events, fires and pathological outbreaks, which exert significant (and still poorly quantified) economic impacts, despite their intrinsic resilience. How forest management addresses these challenges will have profound effects on human health, environmental diversity, (ecological and economic) productivity and the ability of forest ecosystems to recovery from exogenous shocks. Assuming forests as ensuring ecosystem services that are vital to society and human well-being, in addition to providing wood material, a better knowledge of forest ecosystems appears a key requirement to delineate a developmental strategy that guarantees environmental protection objectives and achievement of climate and energy targets. In the context of Sustainable Development Goals of the United Nations 2030 Agenda, the information available on forest management practices in Europe still seems not completely suitable to provide a comprehensive overview of ecosystem conditions, their economic value, and their biodiversity. Based on a literature review, the present contribution focuses on recent dynamics of the forestry sector in Europe, delineating the inherent complexity in the environmental-economic nexus. Additionally, the extensive use of a key natural resource such as wood exerts social implications for local districts adapting to ecological change-from climate warming to landscape transformations. In line with earlier studies, our paper confirms the role of the technical-economic dimension of forestry in sustainable development paths of districts and regions, affecting together (i) short-term economic dynamics, (ii) the growth prospects of the sector, (iii) the organization of the supply chain, (iv) the interconnections between companies, and (v) investment strategies at large. One of the major issues is the low reliability of official statistics to provide a coherent picture of the actual status of forest resources. At the same time, forestry practices are pivotal in maintaining habitats and species while increasing the timber production that remains (too) sustainable. This is the policy direction constantly given by the European Commission to stimulate over time public bodies and private (in whose hands is about 60% of European forests) to start virtuous paths in the circular economy with considerable repercussions in terms of additional jobs, recycled materials, mt of CO2 equivalent avoided, and increase in community added value. In this context, forestry should assure a more 'holistic' contribution to sustainable development paths at various spatial scales. This means concentrating on both economic and environmental targets based on the identification of significant (ecological-economic) dimensions that may delineate future lines of investigation and policy intervention, while increasing between member countries and regional authorities

SYNTHESIS OF (2-ARYLQUINAZOLIN-4-YL)HYDRAZONES OF 2-HYDROXYBENZALDEHYDES AS POTENTIAL PHOSPHOINOSITIDE 3-KINASE (IP3Kδ) AND CASEIN KINASE 2 (CK2) INHIBITORS

This work was supported by the Ministry of Science and Higher Education of Russian Federation, State Contract no FEUZ-2020-0058 (Н687.42Б.223/20)

SYNTHESIS AND PHOTOPHYSICAL PROPERTIES OF 2-ARYL-4-(4-CYANOPHENYL)QUINAZOLINES

This work was supported by the Russian Scientific Foundation (project 22-23-00006)

2-AZINYL QUINAZOLINES: SYNTHESIS AND PHOTOPHYSICAL PROPERTIES

This work was supported by the Russian Scientific Foundation (project 22-23-00006)

Workplace Violence among Female Sex Workers Who Use Drugs in Vancouver, Canada: Does Client Targeted Policing Increase Safety?

Workplace violence, by clients or predators, poses serious negative health consequences for sex workers. In 2013, the Vancouver (British Columbia), Canada Police Department changed their guidelines with the goal of increasing safety for sex workers by focusing law enforcement on clients and third parties, but not sex workers. We sought to examine the trends and correlates of workplace violence among female sex workers (FSW) before and after the guideline change, using data collected from prospective cohorts of persons who use illicit drugs in Vancouver, Canada. Among 259 FSW, 21.0% reported workplace violence at least once during the study period between 2008 and 2014. There was no statistically significant change in rates of workplace violence after the guideline change. In our multivariable analysis, daily heroin use was independently associated with workplace violence. The 2013 policing guideline change did not appear to have resulted in decreased reports of workplace violence. Increased access to opioid agonist therapies may reduce workplace violence among drug-using FSW