22 research outputs found

    Applying LU Decomposition of Matrices to Design Anonymity Bilateral Remote User Authentication Scheme

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    We apply LU decomposition of matrices to present an anonymous bilateral authentication scheme. This paper aims at improving security and providing more excellent performances for remote user authentication scheme. The proposed scheme can provide bilateral authentication and session key agreement, can quickly check the validity of the input password, and can really protect the user anonymity. The security of the proposed scheme is based on the discrete logarithm problem (DLP), Diffie-Hellman problem (DHP), and the one-way hash function. It can resist various attacks such as insider attack, impersonation attack, server spoofing attack, and stolen smart card attack. Moreover, the presented scheme is computationally efficient for real-life implementation

    Experimental test of the Jarzynski equality in a single spin-1 system using high-fidelity single-shot readouts

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    The Jarzynski equality (JE), which connects the equilibrium free energy with non-equilibrium work statistics, plays a crucial role in quantum thermodynamics. Although practical quantum systems are usually multi-level systems, most tests of the JE were executed in two-level systems. A rigorous test of the JE by directly measuring the work distribution of a physical process in a high-dimensional quantum system remains elusive. Here, we report an experimental test of the JE in a single spin-1 system. We realized nondemolition projective measurement of this three-level system via cascading high-fidelity single-shot readouts and directly measured the work distribution utilizing the two-point measurement protocol. The validity of the JE was verified from the non-adiabatic to adiabatic zone and under different effective temperatures. Our work puts the JE on a solid experimental foundation and makes the NV center system a mature toolbox to perform advanced experiments of stochastic quantum thermodynamics

    Experimental study on the principle of minimal work fluctuations

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    The central quantity in the celebrated quantum Jarzynski equality is e−βWe^{-\beta W}, where WW is work and β\beta is the inverse temperature. The impact of quantum randomness on the fluctuations of e−βWe^{-\beta W} and hence on the predictive power of the Jarzynski estimator is an important problem. Working on a single nitrogen-vacancy center in diamond and riding on an implementation of two-point measurement of non-equilibrium work with single-shot readout, we have conducted a direct experimental investigation of the relationship between the fluctuations of e−βWe^{-\beta W} and adiabaticity of non-equilibrium work protocols. It is observed that adiabatic processes minimize the variance of e−βWe^{-\beta W}, thus verifying an early theoretical concept, the so-called principle of minimal work fluctuations. Furthermore, it is experimentally demonstrated that shortcuts-to-adiabaticity control can be exploited to minimize the variance of e−βWe^{-\beta W} in fast work protocols. Our work should stimulate further experimental studies of quantum effects on the bias and error in the estimates of free energy differences based on the Jarzynski equality

    Cryo-EM structures of lipopolysaccharide transporter LptB2FGC in lipopolysaccharide or AMP-PNP-bound states reveal its transport mechanism

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    Lipopolysaccharides (LPS) of Gram-negative bacteria are critical for the defence against cytotoxic substances and must be transported from the inner membrane (IM) to the outer membrane (OM) through a bridge formed by seven membrane proteins (LptBFGCADE). The IM component LptB2FG powers the process through a yet unclarified mechanism. Here we report three high-resolution cryo-EM structures of LptB2FG alone and complexed with LptC (LptB2FGC), trapped in either the LPS- or AMP-PNP-bound state. The structures reveal conformational changes between these states and substrate binding with or without LptC. We identify two functional transmembrane arginine-containing loops interacting with the bound AMP-PNP and elucidate allosteric communications between the domains. AMP-PNP binding induces an inward rotation and shift of the transmembrane helices of LptFG and LptC to tighten the cavity, with the closure of two lateral gates, to eventually expel LPS into the bridge. Functional assays reveal the functionality of the LptF and LptG periplasmic domains. Our findings shed light on the LPS transport mechanism

    Machine learning in 3D auto-filling alveolar cleft of CT images to assess the influence of alveolar bone grafting on the development of maxilla

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    Abstract Background Machine learning based auto-segmentation of 3D images has been developed rapidly in recent years. However, the application of this new method in the research of patients with unilateral cleft lip and palate (UCLP) is very limited. In this study, a machine learning algorithm utilizing 3D U-net was used to automatically segment the maxilla, fill the cleft and evaluate the alveolar bone graft in UCLP patients. Cleft related factors and the surgery impact on the development of maxilla were analyzed. Methods Preoperative and postoperative computed tomography images of 32 patients (64 images) were obtained. The deep-learning-based protocol was used to segment the maxilla and defect, followed by manual refinement. Paired t-tests and Mann-Whitney tests were performed to reveal the changes of the maxilla after surgery. Two-factor, two-level analysis for repeated measurement was used to examine the different trends of growth on the cleft and non-cleft sides of the maxilla. Pearson and Spearman correlations were used to explore the relationship between the defect and the changes of the maxillary cleft side. Results One-year after the alveolar bone grafting surgery, different growth amount was found on the cleft and non-cleft sides of maxilla. The maxillary length (from 34.64 ± 2.48 to 35.67 ± 2.45 mm) and the alveolar length (from 36.58 ± 3.21 to 37.63 ± 2.94 mm) increased significantly only on the cleft side while the maxillary anterior width (from 11.61 ± 1.61 to 12.01 ± 1.41 mm) and posterior width (from 29.63 ± 2.25 to 30.74 ± 2.63 mm) increased significantly only on the non-cleft side after surgery. Morphology of the cleft was found to be related to the pre-surgical maxillary dimension on the cleft side, while its correlation with the change of the maxilla after surgery was low or not statistically significant. Conclusion The auto-segmentation of the maxilla and the cleft could be performed very efficiently and accurately with the machine learning method. Asymmetric growth was found on the cleft and non-cleft sides of the maxilla after alveolar bone graft in UCLP patients. The morphology of the cleft mainly contributed to the pre-operation variance of the maxilla but had little impact on the maxilla growth after surgery

    Microbial Interactions Within Multiple-Strain Biological Control Agents Impact Soil-Borne Plant Disease

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    Major losses of crop yield and quality caused by soil-borne plant diseases have long threatened the ecology and economy of agriculture and forestry. Biological control using beneficial microorganisms has become more popular for management of soil-borne pathogens as an environmentally friendly method for protecting plants. Two major barriers limiting the disease-suppressive functions of biocontrol microbes are inadequate colonization of hosts and inefficient inhibition of soil-borne pathogen growth, due to biotic and abiotic factors acting in complex rhizosphere environments. Use of a consortium of microbial strains with disease inhibitory activity may improve the biocontrol efficacy of the disease-inhibiting microbes. The mechanisms of biological control are not fully understood. In this review, we focus on bacterial and fungal biocontrol agents to summarize the current state of the use of single strain and multi-strain biological control consortia in the management of soil-borne diseases. We discuss potential mechanisms used by microbial components to improve the disease suppressing efficacy. We emphasize the interaction-related factors to be considered when constructing multiple-strain biological control consortia and propose a workflow for assembling them by applying a reductionist synthetic community approach.Peer Reviewe

    Study on electrochemical mechanical polishing process of silicon carbide crystal

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    To solve the problem of low polishing efficiency of silicon carbide crystal, electrochemical mechanical polishing (ECMP) of silicon carbide was carried out to study the effect of NaOH, NaNO3 and H3PO4 electrolytes on electrochemical oxidation of silicon carbide. NaNO3 of 0.6 mol/L was selected as the electrolyte in the ECMP process and so were the diamond-alumina mixed abrasive particles. The influence of load, rotational speed, voltage and particle size on the surface quality and material removal rate of ECMP silicon carbide was studied by using orthogonal experiment. With the optimized processing parameters, the combined polishing experiment can achieve a high-efficiency material removal rate of 20.259 μm/h in the rough polishing stage, and finally obtain the surface roughness of Sa 0.408 nm through precision polishing

    Identification of Vibration Events in Rotating Blades Using a Fiber Optical Tip Timing Sensor

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    The blade tip timing (BTT) technique has been widely used in rotation machinery for non-contact blade vibration measurements. As BTT data is under-sampled, it requires complicated algorithms to reconstruct vibration parameters. Before reconstructing the vibration parameters, the right data segment should first be extracted from the massive volumes of BTT data that include noise from blade vibration events. This step requires manual intervention, is highly dependent on the skill of the operator, and has also made it difficult to automate BTT technique applications. This article proposes an included angle distribution (IAD) correlation method between adjacent revolutions to identify blade vibration events automatically in real time. All included angles of the rotor between any two adjacent blades were accurately detected by only one fiber optical tip timing sensor. Three formulas for calculating IAD correlation were then proposed to identify three types of blade vibration events: the blades’ overall vibrations, vibration of the adjacent two blades, and vibration of a specific blade. Further, the IAD correlation method was optimized in the calculating process to reduce computation load when identifying every blade’s vibration events. The presented IAD correlation method could be used for embedded, real-time, and automatic processing applications. Experimental results showed that the proposed method could identify all vibration events in rotating blades, even small events which may be wrongly identified by skillful operators
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