Cryogenic Q-factor measurement of optical substrates for optimization of gravitational wave detectors

Future generations of gravitational wave interferometers are likely to be operated at cryogenic temperatures because one of the sensitivity limiting factors of the present generation is the thermal noise of end mirrors and beam splitters that occurs in the optical substrates as well as in the dielectric coatings. A possible method for minimizing thermal noise is cooling to cryogenic temperatures, maximizing the mechanical quality factor Q, and maximizing the eigenfrequencies of the substrate. We present experimental details of a new cryogenic apparatus that is suitable for the measurement of the temperature-dependent Q-factor of reflective, transmissive as well as nano-structured grating optics down to 5 K. In particular, the SQUID-based and the optical interferometric approaches to the measurement of the amplitude of vibrating test bodies are compared and the method of ring-down recording is described

Demineralization of Enamel in Primary Second Molars Related to Properties of the Enamel

Enamel structure is of importance in demineralization. Differences in porosity in enamel effect the rate of demineralization, seen between permanent and deciduous teeth. Individual differences have been shown in the mean mineral concentration values in enamel, the role of this in demineralization is not thoroughly investigated. The aim of this study was to study variations of depths of artificial lesions of demineralization and to analyze the depth in relation to variations in the chemical and mineral composition of the enamel. A demineralized lesion was created in second primary molars from 18 individuals. Depths of lesions were then related to individual chemical content of the enamel. Enamel responded to demineralization with different lesion depths and this was correlated to the chemical composition. The carbon content in sound enamel was shown to be higher where lesions developed deeper. The lesion was deeper when the degree of porosity of the enamel was higher

Rapid and selective absorption of plant defense compounds from the gut of a sequestering insect

Many herbivorous insects exploit defense compounds produced by their host plants for protection against predators. Ingested plant defense compounds are absorbed via the gut epithelium and stored in the body, a physiological process that is currently not well understood. Here, we investigated the absorption of plant defense compounds from the gut in the horseradish flea beetle, Phyllotreta armoraciae, a specialist herbivore known to selectively sequester glucosinolates from its brassicaceous host plants. Feeding experiments using a mixture of glucosinolates and other glucosides not found in the host plants showed a rapid and selective uptake of glucosinolates in adult beetles. In addition, we provide evidence that this uptake mainly takes place in the foregut, whereas the endodermal midgut is the normal region of absorption. Absorption via the foregut epithelium is surprising as the apical membrane is covered by a chitinous intima. However, we could show that this cuticular layer differs in its structure and overall thickness between P. armoraciae and a non-sequestering leaf beetle. In P. armoraciae, we observed a thinner cuticle with a less dense chitinous matrix, which might facilitate glucosinolate absorption. Our results show that a selective and rapid uptake of glucosinolates from the anterior region of the gut contributes to the selective sequestration of glucosinolates in P. armoraciae

From Scepticism to Liberalism? Bernard Williams, the Foundations of Liberalism and Political Realism.

Bernard Williams was an ethical sceptic, but he was also a proponent of liberalism. To what extent can one finally be both? This article explores this question through a particular emphasis on Williams, but seeks to draw wider lessons regarding what ethical scepticism should and should not amount to. It shows how ethical scepticism can be reconciled with a commitment to what Williams, following Judith Shklar, called ‘the liberalism of fear’, which is revealed as an ecumenical outlook for different stripes of ethical sceptic. The article concludes by drawing some lessons for the recent ‘realist’ turn in political theory.Research for this article was undertaken while I was the recipient of an Arts and Humanities Research Council PhD studentship at the University of Cambridge, and was later supported by the Cambridge Faculty of History’s Prince Consort and Thirlwall fund

Taking nature into lab: biomineralization by heavy metal-resistant streptomycetes in soil

Biomineralization by heavy metal-resistant streptomycetes was tested to evaluate the potential influence on metal mobilities in soil. Thus, we designed an experiment adopting conditions from classical laboratory methods to natural conditions prevailing in metal-rich soils with media spiked with heavy metals, soil agar, and nutrientenriched or unamended soil incubated with the bacteria. As a result, all strains were able to form struvite minerals (MgNH4PO4 6H2O) on tryptic soy broth (TSB)-media supplemented with AlCl3, MnCl2 and CuSO4, as well as on soil agar. Some strains additionally formed struvite on nutrient-enriched contaminated and control soil, as well as on metal contaminated soil without addition of media components. In contrast, switzerite (Mn3(PO4)2 7H2O) was exclusively formed on minimal media spiked with MnCl2 by four heavy metal-resistant strains, and on nutrient-enriched control soil by one strain. Hydrated nickel hydrogen phosphate was only crystallized on complex media supplemented with NiSO4 by most strains. Thus, mineralization is a dominant property of streptomycetes, with different processes likely to occur under laboratory conditions and sub-natural to natural conditions. This new understanding might have implications for our understanding of biological metal resistance mechanisms. We assume that biogeochemical cycles, nutrient storage and metal resistance might be affected by formation and re-solubilization of minerals like struvite in soil at microscale

A person-centered perspective on working with people who have experienced psychological trauma and helping them move forward to posttraumatic growth

Over the past decade posttraumatic growth (PTG) has become a major topic for theory, research and practice in mainstream trauma psychology. The aim of this paper is to discuss the implications of PTG for the person-centered approach. It is argued that PTG provides a new non-medical language for understanding psychological trauma that is consistent with the person-centered approach. Person-centered personality theory provides an explanation for how PTG arises and leads to new testable predictions for research into how person-centered therapy may be able to facilitate PTG