A pilot study of a text messaging intervention to modify illness and medication beliefs amongst patients diagnosed with inflammatory bowel disease

Intentional and unintentional medication non-adherence is a particular challenge for patients with inflammatory bowel disease (IBD). Non-adherence can affect patients’ quality of life, which can result in unfavorable treatment outcomes, more hospitalizations, and higher healthcare-related costs. The purpose of this study was to assess whether a tailored text message intervention designed to modify illness and medication adherence beliefs in patients with IBD would increase treatment compliance and change patients’ illness perceptions and medication concerns. This pilot study utilized a pre-test-post-test non-randomized design. A sample of 32 IBD patients was recruited within the UK. Participants’ medication beliefs and illness perception scores determined the set of tailored daily text messages, which were sent to patients over duration of 12 weeks. Medication adherence increased post-intervention, as “forgetting to take medication” decreased while “never” forgetting to take medication increased over time. A significant increase in treatment control and coherence and a decreased level of concern surrounding their condition was evident. Participants’ level of concern towards their medications changed during the 12 weeks, with a baseline mean concern score of 3.08 (.57) in comparison to the 12 weeks mean concern score of 2.89 (.59), which is statistically different, t (31) = 2.16, p < .038, r = .36 (medium effect). Sixty-six percent of participants from the baseline were aware of the necessity of their medication: “without my medication I would become ill.” The results have direct implications for improving medication adherence and changing illness and medication beliefs. This study validated the benefits of text messages and highlighted the importance of addressing these beliefs in order to understand the reasons for non-adherence fully

Novel schemes for measurement-based quantum computation

We establish a framework which allows one to construct novel schemes for measurement-based quantum computation. The technique further develops tools from many-body physics - based on finitely correlated or projected entangled pair states - to go beyond the cluster-state based one-way computer. We identify resource states that are radically different from the cluster state, in that they exhibit non-vanishing correlation functions, can partly be prepared using gates with non-maximal entangling power, or have very different local entanglement properties. In the computational models, the randomness is compensated in a different manner. It is shown that there exist resource states which are locally arbitrarily close to a pure state. Finally, we comment on the possibility of tailoring computational models to specific physical systems as, e.g. cold atoms in optical lattices.Comment: 5 pages RevTeX, 1 figure, many diagrams. Title changed, presentation improved, material adde

The Spectral Dimension of 2D Quantum Gravity

We show that the spectral dimension d_s of two-dimensional quantum gravity coupled to Gaussian fields is two for all values of the central charge c <= 1. The same arguments provide a simple proof of the known result d_s= 4/3 for branched polymers.Comment: 7 pages, Late

Quantum Teleportation of Optical Quantum Gates

We show that a universal set of gates for quantum computation with optics can be quantum teleported through the use of EPR entangled states, homodyne detection, and linear optics and squeezing operations conditioned on measurement outcomes. This scheme may be used for fault-tolerant quantum computation in any optical scheme (qubit or continuous variable). The teleportation of nondeterministic nonlinear gates employed in linear optics quantum computation is discussed.Comment: 4 pages, 1 figure, published versio

Necessary and sufficient conditions for bipartite entanglement

Necessary and sufficient conditions for bipartite entanglement are derived, which apply to arbitrary Hilbert spaces. Motivated by the concept of witnesses, optimized entanglement inequalities are formulated solely in terms of arbitrary Hermitian operators, which makes them useful for applications in experiments. The needed optimization procedure is based on a separability eigenvalue problem, whose analytical solutions are derived for a special class of projection operators. For general Hermitian operators, a numerical implementation of entanglement tests is proposed. It is also shown how to identify bound entangled states with positive partial transposition.Comment: 7 pages, 2 figur

Can the X(3872) be a 1^{++} four-quark state?

We use QCD spectral sum rules to test the nature of the meson X(3872), assumed to be an exotic four-quark (c\bar{c}q\bar{q}) state with J^{PC}=1^{++}. For definiteness, we work with the current proposed recently by Maiani et al [1], at leading order in \alpha_s, consider the contributions of higher dimension condensates and keep terms which are linear in the light quark mass m_q. We find M_X=(3925+- 127) MeV which is compatible, within the errors, with he experimental candidate X(3872), while the SU(3) breaking-terms lead to an unusual mass-splitting M_{X^{s}}-M_X=- (61+-30) MeV. The mass-difference between the neutral states due to isospin violation of about (2.6-3.9) MeV is much smaller than the value (8+-3) MeV proposed in [1]. For the b-quark, we predict M_{X_b}= (10144+-106) MeV for the X_b(b\bar{b}q \bar{q}), which is much below the {\bar B}B* threshold in contrast to the {\bar B}B* molecule prediction [2], and for the X_b^s(b\bar{b}s \bar{s}), a mass-splitting M_{X^s_{b}}-M_{X_b}=-(121+-182) MeV. Our analysis also indicates that the mass-splitting between the ground state and the radial excitation of about (225~250) MeV is much smaller than in the case of ordinary mesons and is (within the errors) flavour-independent. We also extract the decay constants, analogous to f_\pi, of such mesons, which are useful for further studies of their leptonic and hadronic decay widths. The uncertainties of our estimates are mainly due to the ones from the c and b quark masses.Comment: 16 pages, 10 figures. Version to appear in Phys. Rev.

Mode-Field Radius of Photonic Crystal Fibers Expressed by the V-parameter

We numerically calculate the equivalent mode-field radius of the fundamental mode in a photonic crystal fiber (PCF) and show that this is a function of the V-parameter only and not the relative hole size. This dependency is similar to what is found for graded-index standard fibers and we furthermore show that the relation for the PCF can be excellently approximated with the same general mathematical expression. This is to our knowledge the first semi-analytical description of the mode-field radius of a PCF.Comment: Accepted for Opt. Let

Fast Universal Quantum Computation with Railroad-switch Local Hamiltonians

We present two universal models of quantum computation with a time-independent, frustration-free Hamiltonian. The first construction uses 3-local (qubit) projectors, and the second one requires only 2-local qubit-qutrit projectors. We build on Feynman's Hamiltonian computer idea and use a railroad-switch type clock register. The resources required to simulate a quantum circuit with L gates in this model are O(L) small-dimensional quantum systems (qubits or qutrits), a time-independent Hamiltonian composed of O(L) local, constant norm, projector terms, the possibility to prepare computational basis product states, a running time O(L log^2 L), and the possibility to measure a few qubits in the computational basis. Our models also give a simplified proof of the universality of 3-local Adiabatic Quantum Computation.Comment: Added references to work by de Falco et al., and realized that Feynman's '85 paper already contained the idea of a switch in i

Observing different phases for the dynamics of entanglement in an ion trap

The evolution of the entanglement between two oscillators coupled to a common thermal environment is non-trivial. The long time limit has three qualitatively different behaviors (phases) depending on parameters such as the temperature of the bath ({\em Phys. Rev. Lett.} \textbf{100}, 220401). The phases include cases with non-vanishing long-term entanglement, others with a final disentangled state, and situations displaying an infinite sequence of events of disappearance and revival of entanglement. We describe an experiment to realize these different scenarios in an ion trap. The motional degrees of freedom of two ions are used to simulate the system while the coupling to an extra (central) ion, which is continuously laser cooled, is the gateway to a decohering reservoir. The scheme proposed allows for the observation and control of motional entanglement dynamics, and is an example of a class of simulations of quantum open systems in the non-Markovian regime.Comment: 5 pages, 5 figure