Comparison of Earth rotation excitation in data-constrained and unconstrained atmosphere models

Changes in Earth rotation are strongly related to fluctuations in the angular momentum of the atmosphere, and therefore contain integral information about the atmospheric state. Here we investigate the extent to which observed Earth rotation parameters can be used to evaluate and potentially constrain atmospheric models. This is done by comparing the atmospheric excitation function, computed geophysically from reanalysis data and climate model simulations constrained only by boundary forcings, to the excitation functions inferred from geodetic monitoring data. Model differences are assessed for subseasonal variations, the annual and semiannual cycles, interannual variations, and decadal-scale variations. Observed length-of-day anomalies on the subseasonal timescale are simulated well by the simulations that are constrained by meteorological data only, whereas the annual cycle in length-of-day is simulated well by all models. Interannual length-of-day variations are captured fairly well as long as a model has realistic, time-varying SST boundary conditions and QBO forcing. Observations of polar motion are most clearly relatable to atmospheric dynamics on subseasonal to annual timescales, though angular momentum budget closure is difficult to achieve even for data-constrained atmospheric simulations. Closure of the angular momentum budget on decadal timescales is difficult and strongly dependent on estimates of angular momentum fluctuations due to core-mantle interactions in the solid Earth. Key Points: Earth rotation parameters contain global information about atmospheric dynamics; Length-of-day observations can constrain modeled winds in tropical regions; Polar motion observations can constrain modeled mass movements in midlatitude

High-magnetic field phase diagram and failure of magnetic Gr\"uneisen scaling in LiFePO4_4

We report the magnetic phase diagram of single-crystalline LiFePO$_4$ in magnetic fields up to 58~T and present a detailed study of magneto-elastic coupling by means of high-resolution capacitance dilatometry. Large anomalies at \tn\ in the thermal expansion coefficient $\alpha$ imply pronounced magneto-elastic coupling. Quantitative analysis yields the magnetic Gr\"uneisen parameter $\gamma_{\rm mag}=6.7(5)\cdot 10^{-7}$~mol/J. The positive hydrostatic pressure dependence $dT_{\rm N}/dp = 1.46(11)$~K/GPa is dominated by uniaxial effects along the $a$-axis. Failure of Gr\"uneisen scaling below $\approx 40$~K, i.e., below the peak temperature in the magneto-electric coupling coefficient [\onlinecite{toft2015anomalous}], implies several competing degrees of freedom and indicates relevance of recently observed hybrid excitations~[\onlinecite{yiu2017hybrid}]. A broad and strongly magnetic-field-dependent anomaly in $\alpha$ in this temperature regime highlight the relevance of structure changes. Upon application of magnetic fields $B||b$-axis, a pronounced jump in the magnetisation implies spin-reorientation at $B_{\rm SF} = 32$~T as well as a precursing phase at 29~T and $T=1.5$~K. In a two-sublattice mean-field model, the saturation field $B_{\rm sat,b} = 64(2)$~T enables the determination of the effective antiferromagnetic exchange interaction $J_{\rm af} = 2.68(5)$~meV as well as the anisotropies $D_{\rm b} = -0.53(4)$~meV and $D_{\rm c} = 0.44(8)$~meV

Auditory brainstem measures and genotyping boost the prediction of literacy: A longitudinal study on early markers of dyslexia

Literacy acquisition is impaired in children with developmental dyslexia resulting in lifelong struggle to read and spell. Proper diagnosis is usually late and commonly achieved after structured schooling started, which causes delayed interventions. Legascreen set out to develop a preclinical screening to identify children at risk of developmental dyslexia. To this end we examined 93 preliterate German children, half of them with a family history of dyslexia and half of them without a family history. We assessed standard demographic and behavioral precursors of literacy, acquired saliva samples for genotyping, and recorded speech-evoked brainstem responses to add an objective physiological measure. Reading and spelling was assessed after two years of structured literacy instruction. Multifactorial regression analyses considering demographic information, genotypes, and auditory brainstem encoding, predicted children’s literacy skills to varying degrees. These predictions were improved by adding the standard psychometrics with a slightly higher impact on spelling compared to reading comprehension. Our findings suggest that gene-brain-behavior profiling has the potential to determine the risk of developmental dyslexia. At the same time our results imply the need for a more sophisticated assessment to fully account for the disparate cognitive profiles and the multifactorial basis of developmental dyslexia

An axon initial segment is required for temporal precision in action potential encoding by neuronal populations

Central neurons initiate action potentials (APs) in the axon initial segment (AIS), a compartment characterized by a high concentration of voltage-dependent ion channels and specialized cytoskeletal anchoring proteins arranged in a regular nanoscale pattern. Although the AIS was a key evolutionary innovation in neurons, the functional benefits it confers are not clear. Using a mutation of the AIS cytoskeletal protein \beta IV-spectrin, we here establish an in vitro model of neurons with a perturbed AIS architecture that retains nanoscale order but loses the ability to maintain a high NaV density. Combining experiments and simulations we show that a high NaV density in the AIS is not required for axonal AP initiation; it is however crucial for a high bandwidth of information encoding and AP timing precision. Our results provide the first experimental demonstration of axonal AP initiation without high axonal channel density and suggest that increasing the bandwidth of the neuronal code and hence the computational efficiency of network function was a major benefit of the evolution of the AIS.Comment: Title adjusted, no other change

Biosensors Derived from Copolymers of Vinylferrocene with Various Para Substituted Phenylmaleimides

Smart Parking Lot is a product that allows the user to know how many parking spots are avail- able and where that parking is located. The Smart Parking Lot provides convenience and flexibility to the student efficient parking. People may spend a long time looking for parking that may or may not be available. This project allows drivers to avoid this annoyance by displaying how many parking spots are available at the lot entrance. There will be an application for a cell phone that provides the availability of parking before checking arrival

Novel Non-Halogenated Flame Retardant Compounds

Two different boron compounds, bis(tetramethylammonium) decaborate, TMAD, and bis (tetrabutylammonium) decaborate, TBAD were studied as potential replacements for halogenated flame retardants. Current commercially available, halogenated flame retardants are not environmentally friendly and release strong acids upon burning. TMAD and TBAD were combined with triphenylphosphine oxide and cast in polyurethane films at varying levels. These samples were then cut into strips and burned in a UL-94 flame chamber. These samples were also tested via TGA for degradation temperature. These varying levels were tested via several Design of Experiments constructed within Minitab software. Results thus far have shown the potential for these compound combinations to be used as flame retardants. Studies to determine the optimal ratio of additives for flame retardancy will be presente

Meta‐analysis: rapid infliximab infusions are safe

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/99086/1/apt12389.pd

Bulk, surface and corner free energy series for the chromatic polynomial on the square and triangular lattices

We present an efficient algorithm for computing the partition function of the q-colouring problem (chromatic polynomial) on regular two-dimensional lattice strips. Our construction involves writing the transfer matrix as a product of sparse matrices, each of dimension ~ 3^m, where m is the number of lattice spacings across the strip. As a specific application, we obtain the large-q series of the bulk, surface and corner free energies of the chromatic polynomial. This extends the existing series for the square lattice by 32 terms, to order q^{-79}. On the triangular lattice, we verify Baxter's analytical expression for the bulk free energy (to order q^{-40}), and we are able to conjecture exact product formulae for the surface and corner free energies.Comment: 17 pages. Version 2: added 4 further term to the serie