CARACTERISTIQUES EPIDEMIOLOGIQUES ET CLINIQUES DES ENVENIMATIONS PAR LES INSECTES HYMENOPTERES AU MAROC EPIDEMIOLOGICAL AND CLINICAL CHARACTERISTICS OF THE ENVENOMATIONS CAUSED BY HYMENOPTERA INSECTS IN MOROCCO

In order to reduce the morbidity of envenomations caused by Hymenoptera insects in Morocco, this study evaluates the incidence of those cases in the regions that have been affected by this type of poisoning and describes the epidemiological and clinical characteristics of the poisoned patients. A descriptive retrospective analysis was conducted on 175 cases of envenomation. Data was collected from two sources, the Toxico-monotoring systems and toxicological information, both based on suspected or proven data from The Moroccan Poison Control and Drug Monitoring Center (CAPM) from the 1 January 2008 to 31 December 2011. Entry and statistical analysis were done using Epi Info 2002. According to the results, the region of Tangier-Tetouan has recorded the highest number of poisoned patients (67 cases) with an incidence of 0.0062 per 100 000 inhabitants. The average age of the poisoned population was 21,6±16,9. Male patients were the most affected with 66% of cases (sex ratio (M / F) = 2). Hymenoptera insect bites have occurred most often in urban areas (62% of cases). There was a peak in bites during July, which corresponds to the period of the proliferation of insects (bees-ants...). 75.4% of patients were symptomatic. The most frequent clinical signs were local edema (25.9%), pruritus (20.5%) and localized pain (18.3%). The evolution was favorable in 81% of cases, 2 cases (1%) with had ongoing sequels and no cases of death were recorded. By studying these 175 cases of envenomation caused by Hymenoptera, we offers education and information to the Moroccan population, and an ecological knowledge about hymenopteran species involved, and the proper management of the poisoned for a better outcome

LES RÉACTIONS LOCALES LIÉES AU VACCIN BCG

To evaluate the frequency and severity of associated local reactions to BCG a retrospective study was conducted on the notified in Moroccan Centre Anti Poison and Pharmacovigilance. During this period, 295 cases have been reported following vaccination with BCG local natureMales were the most concerned with 57%. Infants are much more represented (61%) than other age groups. The most local reactions are observed: becegites (37%), abscesses (20%), rash (16%), ulcers (15%), and fistula (12%). Accompanying signs of these local reactions are usually represented by a fever (6%) and lymphadenopathy (2%). BCG was injected intradermally in 87% of cases, followed by the intramuscular route (8%) and the subcutaneous route in 5% of cases. According to the classification of severity of the WHO ART, these reactions were severe in 18% of cases, moderate in 69% and severe in 14% of cases. The relation of cause and effect between BCG vaccination and the occurrence of local reactions is well established with 46% of probable cases and 7% of cases while some is possible in 46%, and excluded in 1%. The outcome was favorable in 85%, 14% recovered with sequelae and 1% was fatal