216 research outputs found
PERCEPÇÃO DO PROFESSOR DE GEOGRAFIA SOBRE O ENSINO DA GEOMORFOLOGIA NA EDUCAÇÃO BÁSICA: UM ESTUDO NAS ESCOLAS PÚBLICAS DE BOA VISTA – RORAIMA
O estudo objetiva analisar a percepção do professor de Geografia sobre a Geomorfologia na Educação Básica, em três escolas públicas localizadas no centro e na zona norte da cidade de Boa Vista/Roraima. A metodologia caracterizou-se por ser exploratória e descritiva, foi realizada investigação in loco através de entrevista estruturada. Os resultados demonstraram que os professores sentem dificuldades em ministrar conteúdos de Geomorfologia, principalmente pela falta de formação continuada
Scarce fire activity in north and north-western Amazonian forests during the last 10,000 years
Dificuldades Enfrentadas Pelos Indígenas Durante A Permanência Em Uma Casa De Saúde Indígena Na Região Amazônica/brasil
The National Policy of Health Care to the Indigenous Peoples (PNASI) was established by the Ministry of Health restructuring the Primary Care to Indigenous Health, following the principles and guidelines from the Unified Health System (SUS). This study aims to identify the difficulties faced by the indigenous peoples during the stay in the Indigenous Health Center (Casai) in Santarém (PA), in the Amazon region. It is an exploratory qualitative study, whose approach was through semi-structured interviews, recorded and transcribed, with 15 indigenous people from five ethnic groups, assisted by the Casai (Mawayana, Tunayana, Wai-wai, Tiriyó and Katwena), with help from a translator acquainted with the dialects. We used the content analysis arising from thematic categories: the difficulties faced during the adaptation period in the Casai/Santarém, the feeling about leaving the indigenous land and the perspectives regarding the improvements during the stay. We consider that, despite the increasing changes and advances in indigenous health in Brazil, improvements that can truly meet the health peculiarities of each ethnic group are necessary. © 2016, UNIV SAOPAULO. All rights reserved.25492092
X chromosome inactivation does not necessarily determine the severity of the phenotype in Rett syndrome patients
Rett syndrome (RTT) is a severe neurological disorder usually caused by mutations in the MECP2 gene. Since the MECP2 gene is located on the X chromosome, X chromosome inactivation (XCI) could play a role in the wide range of phenotypic variation of RTT patients; however, classical methylation-based protocols to evaluate XCI could not determine whether the preferentially inactivated X chromosome carried the mutant or the wild-type allele. Therefore, we developed an allele-specific methylation-based assay to evaluate methylation at the loci of several recurrent MECP2 mutations. We analyzed the XCI patterns in the blood of 174 RTT patients, but we did not find a clear correlation between XCI and the clinical presentation. We also compared XCI in blood and brain cortex samples of two patients and found differences between XCI patterns in these tissues. However, RTT mainly being a neurological disease complicates the establishment of a correlation between the XCI in blood and the clinical presentation of the patients. Furthermore, we analyzed MECP2 transcript levels and found differences from the expected levels according to XCI. Many factors other than XCI could affect the RTT phenotype, which in combination could influence the clinical presentation of RTT patients to a greater extent than slight variations in the XCI pattern
Classification of antimicrobial resistance using artificial neural networks and the relationship of 38 genes associated with the virulence of Escherichia coli isolates from broilers
Commentaries on Viewpoint: Using V̇o<sub>2max</sub> as a marker of training status in athletes - can we do better?
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