258 research outputs found
Super-A-polynomials for Twist Knots
We conjecture formulae of the colored superpolynomials for a class of twist
knots where p denotes the number of full twists. The validity of the
formulae is checked by applying differentials and taking special limits. Using
the formulae, we compute both the classical and quantum super-A-polynomial for
the twist knots with small values of p. The results support the categorified
versions of the generalized volume conjecture and the quantum volume
conjecture. Furthermore, we obtain the evidence that the Q-deformed
A-polynomials can be identified with the augmentation polynomials of knot
contact homology in the case of the twist knots.Comment: 22+16 pages, 16 tables and 5 figures; with a Maple program by Xinyu
Sun and a Mathematica notebook in the ancillary files linked on the right; v2
change in appendix B, typos corrected and references added; v3 change in
section 3.3; v4 corrections in Ooguri-Vafa polynomials and quantum
super-A-polynomials for 7_2 and 8_1 are adde
High incidence of silent myocardial ischemia in elderly patients with non insulin-dependent diabetes mellitus
Celem badania byĹa ocena czÄstoĹci wystÄpowania
niemego niedokrwienia miÄĹnia sercowego u bezobjawowych
chorych na cukrzycÄ w podeszĹym wieku
(> 60 lat). WstÄpnym etapem badania byĹa maksymalna
prĂłba wysiĹkowa na bieĹźni ruchomej. SpoĹrĂłd
140 chorych u 54 (38,6%) nie udaĹo siÄ osiÄ
gnÄ
Ä
diagnostycznego poziomu wysiĹku podczas
prĂłby lub nie moĹźna jej byĹo wykonaÄ z innych przyczyn,
u 39 z 86 chorych (45,3%) uzyskano pozytywny
wynik prĂłby wysiĹkowej. W drugim etapie tej pracy
u 93 chorych z dodatniÄ
prĂłbÄ
wysiĹkowÄ
, ale
u ktĂłrych nie moĹźna byĹo uzyskaÄ maksymalnego
wysiĹku, wykonano scyntygrafiÄ z uĹźyciem talu w
teĹcie z dipirydamolem. U 39 z 93 chorych (41,9%),
u ktĂłrych wystÄ
piĹy zaburzenia perfuzji, rozpoznano
nieme niedokrwienie miÄĹnia sercowego. U 18
chorych z niemym niedokrwieniem miÄĹnia sercowego,
ktĂłrzy wyrazili zgodÄ, wykonano koronarografiÄ.
U 17 spoĹrĂłd 18 chorych (94,4%) stwierdzono
znacznego stopnia zwÄĹźenia naczyĹ wieĹcowych,
co potwierdziĹo duĹźe znaczenie predykcyjne tej metody.
PodsumowujÄ
c, stwierdzono, Ĺźe czÄstoĹÄ niemego niemego
niedokrwienia miÄĹnia sercowego u chorych
na cukrzycÄ typu 2 w podeszĹym wieku jest bardzo
wysoka (26,3%). Te wyniki sugerujÄ
, Ĺźe wczesna
intensywna diagnostyka zmian w naczyniach wieĹcowych
moĹźe siÄ okazaÄ niezbÄdna jako uzupeĹnienie
rutynowego postÄpowania w tej grupie chorych.The present study was designed reveal the incidence
of silent myocardial ischemia in asymptomatic
elderly non-insulin-dependent diabetic (NIDDM) patients
(aged over 60 years). As a first step screening,
maximal treadmill exercise test was performed. Of
140 patients studied, 54 (38.6%) were unable or not
expected to achieve diagnostic levels of exercise
during treadmill testing. A positive exercise test was
noted in 39 of 86 (45.3%) subjects. As a second step
examination, dipyridamole thallium scintigraphy
was performed for 93 subjects who exhibited a positive
exercise test and could not perform a maximal
exercise test. Abnormal perfusion pattern was
found in 39 of 93 (41.9%), who were finally considered to have a silent myocardial ischemia. Coronary
angiography was performed in 18 subjects with
diagnosis of silent myocardial ischemia, who gave
their consent. Significant coronary artery stenosis
was in fact found in 17 of 18 (94.4%) subjects studied,
confirming a very high positive predictive value
of this diagnostic procedure. In conclusion, elderly
NIDDM patients (aged over 60 years) had an
extremely high prevalence (estimated 26.3%) of silent
myocardial ischemia. This evidence suggests that
early and intensive detection may be needed as
a part of routine care for this grou
Constraints on chiral operators in N=2 SCFTs
Open Access, Š The Authors. Article funded by SCOAP3.
This article is distributed under the terms of the Creative Commons
Attribution License (
CC-BY 4.0
), which permits any use, distribution and reproduction in
any medium, provided the original author(s) and source are credited
EFFECTS OF LOW-DOSE-GAMMA RAYS ON THE IMMUNE SYSTEM OF DIFFERENT ANIMAL MODELS OF DISEASE
We reviewed the beneficial or harmful effects of low-dose ionizing radiation on several diseases based on a search of the literature. The attenuation of autoimmune manifestations in animal disease models irradiated with low-dose Îł-rays was previously reported by several research groups, whereas the exacerbation of allergic manifestations was described by others. Based on a detailed examination of the literature, we divided animal disease models into two groups: one group consisting of collagen-induced arthritis (CIA), experimental encephalomyelitis (EAE), and systemic lupus erythematosus, the pathologies of which were attenuated by low-dose irradiation, and another group consisting of atopic dermatitis, asthma, and Hashimotoâs thyroiditis, the pathologies of which were exacerbated by low-dose irradiation. The same biological indicators, such as cytokine levels and Tcell subpopulations, were examined in these studies. Low-dose irradiation reduced interferon (IFN)-gamma (Îł) and interleukin (IL)-6 levels and increased IL-5 levels and the percentage of CD4+CD25+Foxp3+Treg cells in almost all immunological disease cases examined. Variations in these biological indicators were attributed to the attenuation or exacerbation of the diseaseâs manifestation. We concluded that autoimmune diseases caused by autoantibodies were attenuated by low-dose irradiation, whereas diseases caused by antibodies against external antigens, such as atopic dermatitis, were exacerbated
Generalized Toda Theory from Six Dimensions and the Conifold
Recently, a physical derivation of the Alday-Gaiotto-Tachikawa correspondence
has been put forward. A crucial role is played by the complex Chern-Simons
theory arising in the 3d-3d correspondence, whose boundary modes lead to Toda
theory on a Riemann surface. We explore several features of this derivation and
subsequently argue that it can be extended to a generalization of the AGT
correspondence. The latter involves codimension two defects in six dimensions
that wrap the Riemann surface. We use a purely geometrical description of these
defects and find that the generalized AGT setup can be modeled in a pole region
using generalized conifolds. Furthermore, we argue that the ordinary conifold
clarifies several features of the derivation of the original AGT
correspondence.Comment: 27+2 pages, 3 figure
Prevalence of adrenal masses in Japanese patients with type 2 diabetes mellitus
<p>Abstract</p> <p>Introduction</p> <p>To date, there have been no reports on the prevalence of adrenal masses in type 2 diabetic patients. The present study aimed to evaluate the prevalence of adrenal incidentaloma in type 2 diabetic patients in Japan.</p> <p>Subjects</p> <p>We retrospectively evaluated the presence of adrenal masses using abdominal CT scans in 304 type 2 diabetic patients. In those with adrenal masses, we examined the hormone production capacity of the adrenal mass.</p> <p>Results</p> <p>Fourteen patients (4.6%) had an adrenal mass. Hormonal analysis identified one case as having subclinical Cushing's syndrome, two with primary aldosteronism. Eleven cases had non-functioning masses.</p> <p>Discussion</p> <p>The reported prevalence of adrenal incidentaloma in normal subjects is 0.6-4.0% in abdominal CT scan series. Our results show a relatively high prevalence of adrenal tumors in diabetic patients. On the other hand, the frequency of functional adenoma in diabetic patients is 21.4%, which is similar to that of normal subjects.</p> <p>Conclusion</p> <p>Although further studies are needed to evaluate the prevalence of adrenal tumors in diabetic patients, our data suggest that evaluation of the presence of adrenal masses may be needed in patients with type 2 diabetes mellitus.</p
- âŚ