Distinguishing hypertension from hypertrophic cardiomyopathy as a cause of left ventricular hypertrophy

Distinguishing Hypertension From Hypertrophic Cardiomyopathy as aCause of Left Ventricular HypertrophyIn most hypertensive patients, left ventricular (LV) wallthickness is normal or only mildly increased (≤13 m

A nonlinear rotational, quasi-2DH, numerical model for spilling wave propagation

The propagation of spilling waves interacting with complex bathymetries was studied by means of a new two-dimensional weakly dispersive, fully nonlinear Boussinesq-type of model. In particular, the governing equations were derived assuming the flow as rotational, and the effects of vorticity due to breaking were included through the surface roller concept, which was defined and implemented on the basis of a new algorithm developed for the purpose. The propagation of vorticity, due to wave breaking, is estimated under the assumption that the effect of convection is leading order with respect to the effect of vorticity-stretching and that the breaking phenomenon does not show high curvature on the horizontal plane. In particular, the dynamic problem is decoupled in a lateral direction considering a series of separated sections in which vorticity is solved. In this way it is possible to obtain rotational information along the domain to a reasonable computational cost. The numerical model was validated in a simple one-dimensional case and then applied to the study of breaking-generated vorticity due to wave motion over a submerged shoal

Random wave run-up with a physically-based Lagrangian shoreline model

n the present paper the run-up of random waves was calculated by means of a numerical method. In situ measurements based on a video imaging technique have been used for the validation of the present numerical model. The on-site run-up measurements have been carried out at Lido Signorino beach, near Marsala, Italy,along a transect, normal to the shore. A video camera and a linear array of rods have been used to obtain field data. Numerical simulations with a 1DH Boussinesq-type of model for breaking waves which takes into account the wave run-up by means of a Lagrangian shoreline model have been carried out. In such simulations random waves of given spectrum have been propagated in a numerical flume having the same beach slope of the measured transect. The comparison between registered and estimated run-up underlined an acceptable agreement. Indeed, the numerical model tends to underestimate the actual R2%, with the maximum underestimate being less than 24%, which is a reasonable error in many cases of engineering interest

Random Wave Run-up with a Physically-based Lagrangian Shoreline Model

AbstractIn the present paper the run-up of random waves was calculated by means of a numerical method. In situ measurements based on a video imaging technique have been used for the validation of the present numerical model. The on-site run-up measurements have been carried out at Lido Signorino beach, near Marsala, Italy,along a transect, normal to the shore. A video camera and a linear array of rods have been used to obtain field data. Numerical simulations with a 1DH Boussinesq-type of model for breaking waves which takes into account the wave run-up by means of a Lagrangian shoreline model have been carried out. In such simulations random waves of given spectrum have been propagated in a numerical flume having the same beach slope of the measured transect. The comparison between registered and estimated run-up underlined an acceptable agreement. Indeed, the numerical model tends to underestimate the actual R2%, with the maximum underestimate being less than 24%, which is a reasonable error in many cases of engineering interest

Increasing Human Papillomavirus Vaccination Intent and Knowledge Through an Educational Intervention

Human papillomavirus (HPV) is a widely discussed topic in healthcare as it affects patients of all genders and ages who partake in sexual activity. The most significant concern it poses to those at risk is HPV-related cancer. Fortunately, a vaccination exists that targets specific strains associated with these types of cancers. Despite evidence-based research supporting the vaccination’s efficacy and safety, lack of awareness and misinformation diminish the receipt of the vaccine and drive the lack of protection. Thus, educational interventions directed at parents and caregivers, which aims to improve their understanding of HPV and the vaccination’s benefits, is key to increasing vaccination rates. This project aims to answer the PICOT question: Does HPV education given to parents and caregivers of children and adolescents between theages of 9 and 17 result in higher HPV vaccination intent and knowledge? Evidence-based articles that use education to improve vaccination rates, intent, or knowledge using different forms of education and different target populations were located. Overall, research supports education to promote HPV-awareness and increasing vaccination uptake to decrease HPV-related cancers. The use of technology to increase knowledge is essential today as the coronavirus pandemic has driven our nation to accomplish social distancing measures while still performing everyday activities. To increase HPV knowledge and vaccination intent through a technology-based educational intervention, Lewin’s Change Theory and the Iowa Model were used to help guide the project using a step-by-step process. For this DNP project, a video on HPV education was delivered and change in HPV knowledge and vaccination intent was measured through Qualtrics XM surveys, which were accessible through a link provided on social media and pediatrician offices. Results revealed that there was no statistical significance amongst demographics, including gender, age, ethnicity, education, and marital status, and a change in overall HPV iv knowledge. However, when analyzing vaccination intent pre-and post-survey, statistical significance (p = 0) was evident as 14/36 (38.89%) of the participants changed whether they intended to vaccinate their child or adolescent from “no” to “yes” after receiving the educational intervention. The project facilitator also found statistical significance (p \u3c 0.001) amongst HPV Knowledge Survey scores from the pre- and post-survey answers as there was a mean increase of -1.22, with a 95% confidence interval ranging from -1.76 to -0.69). Overall, the project addresses the problem of the lack of HPV-related knowledge and vaccination intent amongst caregivers of adolescents and children and furthermore, has the capability of increasing HPV vaccination rates. Nevertheless, limitations and recommendations enhancing implementation and driving sustainability to improve patient outcomes in the future are addressed further. Keywords: human papillomavirus, educational intervention, child or adolescent, guardian, vaccination rate, vaccination inten

Seismological investigations in the Gioia Tauro Basin (southern Calabria, Italy)

This study provides new seismological information to characterize the seismically active area of the Gioia Tauro basin (southern Calabria, Italy). Seismic activity recorded by a temporary network from 1985 to 1994 was analyzed for focal mechanisms, stress tensor inversion, P-wave seismic attenuation and earthquake source parameters estimation. Fault plane solutions of selected events showed a variety of different mechanisms, even if a prevalence of normal dip-slip solutions with prevalent rupture orientations occurring along ca. NE-SW directions was observed. Stress tensor inversion analysis disclosed a region governed mainly by a NW-SE extensional stress regime with a nearly vertical σ1. These results are consistent with the structure movements affecting the studied area and with geodetic data. Furthermore, evaluation of P-waves seismic attenuation and earthquake source parameters of a subset of events highlighted a strong heterogeneity of the crust and the presence of fault segments and/or weakened zones where great stress accumulation or long-rupture propagation are hindered