Synthesis of 2-aryl-1-arylmethyl-1H-benzimidazoles using chlorosulfonic acid at room temperature

AbstractChlorosulfonic acid (ClSO3H) used to be a catalyst for the synthesis of 2-aryl-1-arylmethyl-1H-benzimidazoles which was efficiently simple and convenient. This method afforded short reaction time, easy workup, moderate to excellent isolated yields which make this protocol practical and economically attractive

One-pot synthesis of dihydropyrano[2,3-c]pyrazole derivatives using β-cyclodextrin-SO 3 H as a reusable catalyst in aqueous medium

Abstract: We have developed an expedient and highly efficient β-cyclodextrin-SO 3 H catalyzed approach for the eco-friendly synthesis of dihydropyrano[2,3-c]pyrazole derivatives in aqueous medium. The reaction proceeded smoothly with a range of functionalities within 15-30 min to produce the dihydropyrano[2,3-c]pyrazole scaffolds in good to excellent yields. β-cyclodextrin-SO 3 H can be recycled and reused with an insignificant loss of catalytic activity

Tannic Acid an Efficient Catalyst for the Synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[a]xanthen-11-one Derivatives

Tannic acid explore a highly efficient catalytic activity for the synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[a]xanthen-11-one derivatives in excellent yields via cyclocondensation of aromatic aldehyde, β-naphthol and dimedone. Catalyst having advantages such as it is cheap and biodegradable and the protocol avoids the use of expensive catalyst and toxic solvent. We believe that this methodology is an efficient, simple, highly yielding, time saving and environmentally friendly. DOI: http://dx.doi.org/10.17807/orbital.v7i2.68

Research Paper Solvent free and High yielding Synthesis of new ethyl 2-(ethoxyphosphono)-2-(2- chloroquinolin-3-yl)-1-cyanoethanoates from ethyl 3-(2-chloroquinolin-3-yl)-2- cyanoacrylate

Abstract: Solvent free, and high yielding synthesis of new ethyl 2-(ethoxyphosphono)-2-(2-chloroquinolin-3-yl)-1-cyanoethanoates from ethyl 3-(2-chloroquinolin-3-yl)-2-cyanoacrylate, obtained from 2-chloroquinolin-3-carbaldehydes by using triethylphosphite in the presence of TMSCl at room temperature

Envirocat EPZG Mediated Synthesis of 3,4-Dihydropyrano[c]chromene Derivatives Under Microwave Irradiation in Solvent-free Conditions

A Envirocat EPZG mediated method is developed for the synthesis of 3,4‐dihydropyrano[c]chromene derivatives under microwave irradiation by three component cyclocondensation of 4‐hydroxycoumarin, malononitrile and aromatic aldehydes. The process has been carried out under solvent-free conditions in the presence of very small amount of Envirocat EPZG. Use of ecofriendly readily available catalyst and green reaction media makes this methodology simple, safe, and cost effective. Mild reaction conditions, easy workup procedure, excellent yields and short reaction times are some remarkable features of this work. DOI: http://dx.doi.org/10.17807/orbital.v13i1.1517 </p

Synthesis of new <i>O,O</i> -dialkyl-<i>O</i>-coumarinophosphorothioates and their pesticidal bioassay against <i>HeLicoverpa</i> <i>armigera</i>

339-341A series of compounds O,O-dialkyl-O-coumarinophosphorothioates have been synthesized and screened for pesticidal activities against HeLicoverpa armigera. Some of the compounds (3,4, 6 and 7) show significant activities while rest of the compounds show moderate activities

Environmentally Benign Protocol for the Synthesis of 1,2-dihydro-1-aryl naph- tho [1,2-e] [1,3] oxazine-3-one Derivatives

Abstract: 1,2-dihydro-1-aryl naphtho [1,2-e] [1,3] oxazine-3-one derivatives have been synthesized via one-pot condensation of aromatic aldehyde, β-naphthol and urea using cellulose sulfuric acid (CSA) as catalyst in solvent free condition under microwave irradiation. CSA has efficiently catalyzed the cyclocondensation and enhanced the product yields by reducing reaction time. The uniqueness of CSA is that it is isolable after the reaction and reusable

Morpholinium bisulfate [morH][HSO4]: An efficient and reusable catalyst for the synthesis of bis(indolyl)methanes

Morpholinium bisulfate [morH][HSO4] ionic liquid was found to be an effective catalyst for the condensation reaction of indoles with carbonyl compound at room temperature. Present methodology has several merits such as mild reaction condition, inexpensive catalyst, stable at room temperature and it was also found that this catalyst could be recovered quantitatively and reused without much loss of catalytic activity

An efficient one pot three-component synthesis of dihydropyrano[3,2-c] chromenes using ammonium metavanadate as catalyst

We report ammonium metavanadate catalyzed one-pot synthesis of 3,4-dihydropyrano[3,2-c]chromenes, from aldehydes, active methylene compounds malononitrile and 4-hydroxycoumarin in water:ethanol(1:1) under reflux. The attractive features of this process are mild reaction conditions, short reaction times, easy isolation of products, and excellent yields