Results of studied parameters of buccal films.

<p>Results of studied parameters of buccal films.</p

Kinetics modeling for data of drug release and drug permeation from TZN and MLX containing bi-layer mucoadhesive buccal films.

<p>Kinetics modeling for data of drug release and drug permeation from TZN and MLX containing bi-layer mucoadhesive buccal films.</p

Statistical data table for pharmacokinetic parameters of TZN and MLX obtained from buccal film and oral solution/dispersion.

<p>Statistical data table for pharmacokinetic parameters of TZN and MLX obtained from buccal film and oral solution/dispersion.</p

Statistical data table for pharmacokinetic parameters of TZN and MLX obtained from buccal film and oral solution/dispersion.

<p>Statistical data table for pharmacokinetic parameters of TZN and MLX obtained from buccal film and oral solution/dispersion.</p

Figure showing FTIR spectrum of different ingredients and prepared films.

<p>Figure showing FTIR spectrum of different ingredients and prepared films.</p

Pharmacokinetics of TZN and MLX after administration of SR films and standard oral solution containing 1mg/kg of the drug.

<p>Absorption of TZN from buccal films (A) and from oral solution (B), and MLX from buccal film (C) and oral dispersion (D).</p

Graphical illustration of <i>in-vitro</i> dissolution and <i>ex-vivo</i> permeation of MLX and TZN.

<p>A and B are showing drug release and permeation of MLX while C and D are describing release and permeation of TZN from bilayer mucoadhesive buccal film.</p

Pharmacokinetics of TZN and MLX after administration of buccal films and standard oral solution/dispersion containing 1mg/kg of the drugs.

<p>Pharmacokinetics of TZN and MLX after administration of buccal films and standard oral solution/dispersion containing 1mg/kg of the drugs.</p

Development of Tizanidine HCl-Meloxicam loaded mucoadhesive buccal films: <i>In-vitro</i> and <i>in-vivo</i> evaluation - Fig 1

<p>Image taken by the digital camera (Nikon Coolpix p500) showing shiny and smooth surface of the SR layer of TZN (A) and IR layer of MLX (B), Optical microscopic image of bilayer buccal film taken by an optical microscope at 40X (C) and SEM image of bilayer buccal film taken at 2000X (D) showing uniform mixing of ingredients (blue arrow with white outline is indicating polymeric meshwork while white arrow with blue outline is pointing out the imbedded drug).</p

The <i>MSE</i> of proposed and conventional ratio and product estimators.

The MSE of proposed and conventional ratio and product estimators.</p