2,253 research outputs found
Effects of grain size on cyclic strain localization in polycrystalline nickel
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/29319/1/0000384.pd
Reductions in movement-associated fear are dependent upon graded exposure in chronic low back pain : an exploratory analysis of a modified 3-item fear hierarchy
Objective: To explore the effectiveness of a modified fear hierarchy on measuring improvements in movement-associated fear in chronic low back pain. Methods: A modified 3-item fear hierarchy was created and implemented based on principles of graded exposure. This study was an exploratory analysis of the modified 3-item fear hierarchy from a larger clinical trial data set. Both groups received pain education and exercise, either bodyweight or strength training. Both groups performed item one on the hierarchy, the squat. Only the strength training group performed item 2, the deadlift. Neither group performed item 3, the overhead press. Analysis of Covariance and stepwise linear regression were used to explore results. Results: Improvement in movement-associated fear was conditional upon graded exposure. Both groups improved in the squat movement (p ≤ 0.05), which both performed. Only the strength training group improved in the deadlift (p ≤ 0.01), and neither improved in the overhead press (p ≥ 0.05). Conclusion: Reductions in movement-associated fear are conditional upon graded exposure, based on the use of a novel modified 3-item fear hierarchy. Further research is needed to understand the utility of this tool in a patient-led approach to co-designing a graded exposure-based intervention
A new ERA? Researching the use of Electronic Patient Records Systems in Ambulances
Ambulance services around the world have been introducing electronic patient record systems. If your
trust hasn’t yet, it’s only a matter of time. The business cases for these new systems promise the triple aim
of better health, better healthcare and lower cost
Cyclotomic integers, fusion categories, and subfactors
Dimensions of objects in fusion categories are cyclotomic integers, hence
number theoretic results have implications in the study of fusion categories
and finite depth subfactors. We give two such applications. The first
application is determining a complete list of numbers in the interval (2,
76/33) which can occur as the Frobenius-Perron dimension of an object in a
fusion category. The smallest number on this list is realized in a new fusion
category which is constructed in the appendix written by V. Ostrik, while the
others are all realized by known examples. The second application proves that
in any family of graphs obtained by adding a 2-valent tree to a fixed graph,
either only finitely many graphs are principal graphs of subfactors or the
family consists of the A_n or D_n Dynkin diagrams. This result is effective,
and we apply it to several families arising in the classification of subfactors
of index less then 5.Comment: 47 pages, with an appendix by Victor Ostri
Subfactors of index less than 5, part 3: quadruple points
One major obstacle in extending the classification of small index subfactors
beyond 3+\sqrt{3} is the appearance of infinite families of candidate principal
graphs with 4-valent vertices (in particular, the "weeds" Q and Q' from Part 1
(arXiv:1007.1730)). Thus instead of using triple point obstructions to
eliminate candidate graphs, we need to develop new quadruple point
obstructions. In this paper we prove two quadruple point obstructions. The
first uses quadratic tangles techniques and eliminates the weed Q' immediately.
The second uses connections, and when combined with an additional number
theoretic argument it eliminates both weeds Q and Q'. Finally, we prove the
uniqueness (up to taking duals) of the 3311 Goodman-de la Harpe-Jones subfactor
using a combination of planar algebra techniques and connections.Comment: 21 page
Risk-proportionate clinical trial monitoring: an example approach from a non-commercial trials unit
Background
Some level of monitoring is usually required during a clinical trial to protect the rights and safety of trial participants and to safeguard the quality and reliability of trial results. Although there is increasing support for the use of risk-proportionate approaches to achieve these aims, the variety of methods and lack of an empirical evidence base can present challenges for clinical trial practitioners.
Methods
This paper describes the monitoring methods and procedures that are utilised by a noncommercial clinical trials unit which coordinates a range of clinical trials across a variety of clinical areas with different associated risks.
Results
Monitoring activities and approaches should be selected to be proportionate to the risks identified within a trial. A risk-proportionate approach to monitoring is described giving details of methods that may be considered by clinical trial practitioners during the development of a trial monitoring plan. An example risk assessment and corresponding monitoring plan for a low risk (type A in the Medicines and Healthcare Products Regulatory Agency (MHRA) classification system) pediatric trial is provided for illustration.
Conclusion
We present ideas for developing a monitoring plan for a clinical trial of an investigational medicinal product based on our experience. Alternative approaches may be relevant or preferable in other settings based on inherent risk
Critical temperature of non-interacting Bose gases on disordered lattices
For a non-interacting Bose gas on a lattice we compute the shift of the
critical temperature for condensation when random-bond and onsite disorder are
present. We evidence that the shift depends on the space dimensionality D and
the filling fraction f. For D -> infinity (infinite-range model), using results
from the theory of random matrices, we show that the shift of the critical
temperature is negative, depends on f, and vanishes only for large f. The
connections with analogous results obtained for the spherical model are
discussed. For D=3 we find that, for large f, the critical temperature Tc is
enhanced by disorder and that the relative shift does not sensibly depend on f;
at variance, for small f, Tc decreases in agreement with the results obtained
for a Bose gas in the continuum. We also provide numerical estimates for the
shift of the critical temperature due to disorder induced on a non-interacting
Bose gas by a bichromatic incommensurate potential.Comment: 18 pages, 8 figures; Fig. 8 improved adding results for another value
of q (q=830/1076
Constructing the extended Haagerup planar algebra
We construct a new subfactor planar algebra, and as a corollary a new
subfactor, with the `extended Haagerup' principal graph pair. This completes
the classification of irreducible amenable subfactors with index in the range
, which was initiated by Haagerup in 1993. We prove that the
subfactor planar algebra with these principal graphs is unique. We give a skein
theoretic description, and a description as a subalgebra generated by a certain
element in the graph planar algebra of its principal graph. In the skein
theoretic description there is an explicit algorithm for evaluating closed
diagrams. This evaluation algorithm is unusual because intermediate steps may
increase the number of generators in a diagram.Comment: 45 pages (final version; improved introduction
The Nakayama automorphism of the almost Calabi-Yau algebras associated to SU(3) modular invariants
We determine the Nakayama automorphism of the almost Calabi-Yau algebra A
associated to the braided subfactors or nimrep graphs associated to each SU(3)
modular invariant. We use this to determine a resolution of A as an A-A
bimodule, which will yield a projective resolution of A.Comment: 46 pages which constitutes the published version, plus an Appendix
detailing some long calculations. arXiv admin note: text overlap with
arXiv:1110.454
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