3,828 research outputs found

    Coping with the postponement boundary problem: an empirical investigation in global food supply chains

    Get PDF
    Purpose – The postponement boundary problem entails that duties and cross-border trade complexity can lead companies to geographically postpone operations to downstream global facilities. The present study aims at investigating the problem to provide insights into the drivers behind the choice of different postponement strategies for global food supply chains. Design/methodology/approach – A single case study was conducted considering an Italian company exporting olive oil toward the United States. Two global postponement strategies, previously formalized in the literature, were tailored for food supply chains. A multi-methodological approach was adopted, combining data obtained through exploratory case research with empirically grounded analytical modeling. A sensitivity analysis was also performed, to investigate outcomes related to the considered problem when changing key parameters. Findings – Bulky and heavy packing materials account for a big percentage of finished products’ volume and weight, and this can deeply affect strategies’ cost-effectiveness. Postponing packaging operations could allow for taking advantage of lower tariffs levied on bulk goods, contributing to significantly lower duties to be paid. However, important trade-offs could arise related to the required investments, and the fiscal regulatory frameworks must be carefully examined. Originality/value – This study offers an empirical investigation of the postponement boundary problem, which is largely unexplored in the current literature. It also tackles an understudied empirical context as global food supply chains. It summarizes the drivers behind and explores the costs related to the implementation of different strategies, offering an original quantitative approach that could support practitioners’ decision making. Lastly, it formalizes five propositions that could pave the way for further research inquiries

    Temperature-sensitive protein–DNA dimerizers

    Get PDF
    Programmable DNA-binding polyamides coupled to short peptides have led to the creation of synthetic artificial transcription factors. A hairpin polyamide-YPWM tetrapeptide conjugate facilitates the binding of a natural transcription factor Exd to an adjacent DNA site. Such small molecules function as protein-DNA dimerizers that stabilize complexes at composite DNA binding sites. Here we investigate the role of the linker that connects the polyamide to the peptide. We find that a substantial degree of variability in the linker length is tolerated at lower temperatures. At physiological temperatures, the longest linker tested confers a "switch"-like property on the protein-DNA dimerizer, in that it abolishes the ability of the YPWM moiety to recruit the natural transcription factor to DNA. These observations provide design principles for future artificial transcription factors that can be externally regulated and can function in concert with the cellular regulatory circuitry

    Higgs signals and hard photons at the Next Linear Collider: the ZZZZ-fusion channel in the Standard Model

    Get PDF
    In this paper, we extend the analyses carried out in a previous article for WWWW-fusion to the case of Higgs production via ZZZZ-fusion within the Standard Model at the Next Linear Collider, in presence of electromagnetic radiation due real photon emission. Calculations are carried out at tree-level and rates of the leading order (LO) processes e^+e^-\rightarrow e^+e^- H \ar e^+e^- b\bar b and e^+e^-\rightarrow e^+e^- H \ar e^+e^- WW \ar e^+e^- \mathrm{jjjj} are compared to those of the next-to-leading order (NLO) reactions e^+e^-\rightarrow e^+e^- H (\gamma)\ar e^+e^- b\bar b \gamma and e^+e^-\rightarrow e^+e^- H (\gamma)\ar e^+e^- WW (\gamma) \ar e^+e^- \mathrm{jjjj}\gamma, in the case of energetic and isolated photons.Comment: 12 pages, LaTeX, 5 PostScript figures embedded using epsfig and bitmapped at 100dpi, complete paper including high definition figures available at ftp://axpa.hep.phy.cam.ac.uk/stefano/cavendish_9611.ps or at http://www.hep.phy.cam.ac.uk/theory/papers

    Two minimal incision fasciotomy for chronic exertional compartment syndrome of the lower leg

    Get PDF
    Chronic exertional compartment syndrome (CECS) of the leg is a pathological condition often related to overuse in subject who engage repetitive physical activities. Fascial release is the mainstay of surgical management. The purpose of this study was to evaluate the results obtained with a double incision decompressive fasciotomy. Eighteen consecutive athletes with a diagnosis of anterior and/or lateral CECS of the leg were operated on with a minimal double incision fascial release after a mean period of 4months after onset of symptoms. In 11 cases (61%) CECS was bilateral. Surgery was performed without tourniquet and active mobilization was starting immediately. Sports activities were resumed gradually at a mean period of 25days. The athletes were followed until 2years. All resumed pre-injury level sports activity. Two patients (18%) of the 11 who underwent to bilateral fasciotomy referred a sensation of leg weakness for an average period of 3months. The surgical technique presented in this paper seems to be a good mean to treat anterior and lateral leg CECS. The use of tourniquet is deconselled to obtain an accurate intraoperative haemostasis so reducing the risk of post-operative haematom

    Minimal invasive surgery for coronoid fracture: technical note

    Get PDF
    Operative treatment of coronoid fracture often requires a large dissection of soft tissue, resulting in elbow stiffness and functional limitation. The authors present a minimal invasive, safe technique, useful in the case of isolated coronoid fracture associated with elbow dislocation. This technique does not require soft tissue dissection and allows an early unlimited resumption of sports activitie

    Looking for the Charged Higgs Boson

    Full text link
    This review article starts with a brief introduction to the charged Higgs boson (H^\pm) in the Minimal Supersymmetric Standard Model (MSSM). It then discusses the prospects of a relatively light H^\pm boson search via top quark decay at Tevatron/LHC, and finally a heavy H^\pm boson search at LHC. The viable channels for H^\pm search are identified in both the cases, with particular emphasis on the H^\pm --> tau + nu decay channel. The effects of NLO QCD correction in the SM as well as the MSSM are discussed briefly.Comment: 17 pages with 8 eps figures, Invited review, Reference adde

    Facile Electron Transfer in Atomically Coupled Heterointerface for Accelerated Oxygen Evolution

    Get PDF
    An efficient and cost-effective approach for the development of advanced cata-lysts has been regarded as a sustainable way for green energy utilization. The general guideline to design active and efficient catalysts for oxygen evolution reaction (OER) is to achieve high intrinsic activity and the exposure of more density of the interfacial active sites. The heterointerface is one of the most attractive ways that plays a key role in electrochemical water oxidation. Herein, atomically cluster-based heterointerface catalysts with strong metal support interaction (SMSI) between WMn2O4 and TiO2 are designed. In this case, the WMn2O4 nanoflakes are uniformly decorated by TiO2 particles to create electronic effect on WMn2O4 nanoflakes as confirmed by X-ray absorption near edge fine structure. As a result, the engineered heterointerface requires an OER onset overpotential as low as 200 mV versus reversible hydrogen electrode, which is stable for up to 30 h of test. The outstanding performance and long-term durability are due to SMSI, the exposure of interfacial active sites, and accelerated reaction kinetics. To confirm the synergistic interaction between WMn2O4 and TiO2, and the modification of the electronic structure, high-resolution transmission electron microscopy (HR-TEM), X-ray photoemission spectroscopy (XPS), and X-ray absorption spectroscopy (XAS) are used

    Protocolo de análise para determinação da atividade antioxidante total em hortaliças no sistema beta-caroteno / ácido linoléico.

    Get PDF
    bitstream/CNPH-2010/36126/1/cot-68.pd
    • …
    corecore