Micromamíferos vallesienses del yacimiento La Salle en las Arcillas Rojas de Teruel

El hallazgo de unos restos de micromamiferos en las proximidades del Colegio La Salle de Teruel permite datar la formación de las arcillas rojas conocida con 10s nombres de "Los Monotos", "Formación de Los Tejares" y "Pera1 Formation". La ausencia casi total de fósiles ha hecho que la edad de esa formación fuera largamente discutida. Los fósiles recientemente encontrados permiten atribuirle una edad vallesiense (MN 10 basal). La fauna recogida comprende: Galerix (Parasorex) socialis, Crusafontina excultus, Hispanomys peralensis, Progonomys hispanicus, P. cathalai y Prolagus crusafonti, que se Gade a la de Tetralophodon longirostris, e Hippmion sp

Whole genome sequencing reveals high clonal diversity of Escherichia coli isolated from patients in a tertiary care hospital in Moshi, Tanzania

Abstract Background Limited information regarding the clonality of circulating E. coli strains in tertiary care hospitals in low and middle-income countries is available. The purpose of this study was to determine the serotypes, antimicrobial resistance and virulence genes. Further, we carried out a phylogenetic tree reconstruction to determine relatedness of E. coli isolated from patients in a tertiary care hospital in Tanzania. Methods E. coli isolates from inpatients admitted at Kilimanjaro Christian Medical Centre between August 2013 and August 2015 were fully genome-sequenced at KCMC hospital. Sequence analysis was done for identification of resistance genes, Multi-Locus Sequence Typing, serotyping, and virulence genes. Phylogeny reconstruction using CSI Phylogeny was done to ascertain E. coli relatedness. Stata 13 (College Station, Texas 77,845 USA) was used to determine Cohen’s kappa coefficient of agreement between the phenotypically tested and whole genome sequence predicted antimicrobial resistance. Results Out of 38 E. coli isolates, 21 different sequence types (ST) were observed. Eight (21.1%) isolates belonged to ST131; of which 7 (87.5.%) were serotype O25:H4. Ten (18.4%) isolates belonged to ST10 clonal complex; of these, four (40.0%) were ST617 with serotype O89:H10. Twenty-eight (73.7%) isolates carried genes encoding beta-lactam resistance enzymes. On average, agreement across all drugs tested was 83.9%. Trimethoprim/sulphamethoxazole (co-trimoxazole) showed moderate agreement: 45.8%, kappa =15% and p = 0.08. Amoxicillin-clavulanate showed strongest agreement: 87.5%, kappa = 74% and p = 0.0001. Twenty-two (57.9%) isolates carried virulence factors for host cells adherence and 25 (65.7%) for factors that promote E. coli immune evasion by increasing survival in serum. The phylogeny analysis showed that ST131 clustering close together whereas ST10 clonal complex had a very clear segregation of the ST617 and a mix of the rest STs. Conclusion There is a high diversity of E. coli isolated from patients admitted to a tertiary care hospital in Tanzania. This underscores the necessity to routinely screen all bacterial isolates of clinical importance in tertiary health care facilities. WGS use for laboratory-based surveillance can be an effective early warning system for emerging pathogens and resistance mechanisms in LMICs

Neogene basins in the Eastern Iberian Range.

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The Neogene grabens of the Eastern Iberian Chain

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Mamíferos del turoliense medio en la Rambla de Valdecebro (Teruel)

15 páginas, 10 figuras, 3 tablas, 2 láminas.[ES] La localización de una nueva fauna de mamíferos en la Rambla de Valdecebro ha permitido constatar la presencia del Turoliense medio, edad todavía no documentada en este lugar. La Rambla, situada en las proximidades de la ciudad de Teruel, es muy conocida por la existencia de relevantes yacimientos con mamíferos miocenos. Se describen los roedores, representados por las especies Occitanomys adroveri, Parapodemus barbarae, Ruscinomys schaubi y Eliomys truci, y los macromamíferos, entre los que destaca la abundancia de carnívoros: Indarctos atticus, Baranogale adroveri, Thalasictis aff. hipparionum y Lycyaena chaeretis. El yacimiento, llamado Valdecebro 5 (VDC 5), se sitúa en la parte superior de la zona MN 12. Se incluye un esquema geológico detallado de la Rambla de Valdecebro con la localización estratigráfica de los yacimientos de mamíferos conocidos hasta el momento, así como su integración en el contexto geológico de la fosa de Teruel.[EN] The Valdecebro Rambla, located in the Northeast of Teruel (Central Spain), is knomw by the existence of importante miocene mammal localities: Masía del Barbo, Vivero de Pinos, Arquillo de la Fontana, Arquillo 3, etc. They are all aged between Upper Vallesian and Middle Piocene. A new locality, Valdecebri 5 ( VDC 5), is studied in this paper. It permits us to affirm the presence of Middle Turolian sediments, not yet documented, in the Rambla. The roden fauna contains macromammals are mainly represented by carnivores; Indarctos atticus, Baranogale adroveri. Thalassictis aff. hipparionum and lycyaena chaeretis, further on hipparion concidense concudense and two indetermined artiodactils. The biostratigraphical data of the new bed, just as others known before, are reflected in a detailed geogical sheme of Rambla de Valdecebro. This scheme is placed in the general geogical context of the miocene Teruel Basin.Peer reviewe

Cuesta de la Bajada: un yacimiento del Pleistoceno Medio en Aragón

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Araya et Mira: Nouveaux gisements de Mammifères dans le Miocène inférieur-moyen des chaines ibériques orientales et Mediterranéennes. Conséquences stratigraphiques et structurales.

The Mira and Ribesalbes-Alcora basins (Eastern and Southern Iberian Ranges) have been filled with Neogene, nonmarine and unfolded deposits. The first one has been dated of middle Miocene with the Mira Micromammals. The other one, over the Ribesalbes flora of early Miocene age, yielded the Araya and Mas de Antolino localities with little older Mammals, (MN4). These data show that the alpine compession disapperared in this region before the middle Miocene times.Peer Reviewe

Comparative In Vitro Activities of Caspofungin and Micafungin, Determined Using the Method of the European Committee on Antimicrobial Susceptibility Testing, against Yeast Isolates Obtained in France in 2005-2006▿

The in vitro activities of caspofungin and micafungin against 1,038 yeast isolates have been determined. The caspofungin and micafungin MICs were lower for Candida albicans, Candida glabrata, and Candida tropicalis than for Candida parapsilosis, Candida guilliermondii, and Candida krusei. A clear correlation was seen between the MICs for the two drugs

Up-to-date Spanish continental Neogene synthesis and paleoclimatic interpretation

A synthesis of the Spanish continental Neogene is presented by designing an integrated correlative chart of the Neo" gen-e "succes"Siuns-ofthe "lberian-PeninsuIa-. -Ninemain-sedimentary-breaks-have-been -distinguished-in-most-of-the "basins. They are considered a valuable criteria for correlation as they occur in similar time intervals from basin to basin. The determined sedimentary breaks occur in the Agenian, Ramblian, Middle Aragonian, Late Aragonian, Late Vallesian, Middle Turolian, Late Turolian, Late Ruscinian-Early Villafranchian, and Villafranchian ages. The larger interior basins (Ebro, Tajo, Duero) show a fairly complete Neogene sedimentary record in which the aboye mentioned sedimentary breaks are usually well recognized. A good correlation may be established from basin to basin. Likewise, there is a fairly good correlation among the Upper Miocene-Pliocene sedimentary record of basins spreading out in Levante and southeastern Spain. However, the correlation is not as c1ear in those basins located within the Iberian and Catalan Coastal Ranges, which usually do not show a similar sedimentary pattern. The comparison between Neogene stratigraphic logs in most of the Spanish continental basins and the pattern of global events from currentIy accepted Cenozoic Cyc1e Charts allows recognition of chronological coincidences, especially with regard to the age of seven major sedimentary ruptures (those developed at about 24.5 Ma, 22 Ma, 16 Ma, 13.5 Ma, 9.5 Ma, 5.5 Ma, 3.3 Ma). Evolutionary sedimentary trends in both offshore Mediterranean areas and inland peripheral zones of the Iberian Peninsula show also striking coincidences regarding the chronology of major sedimentary breaks observed in continental successions. Paleoc1imatic curves for the Spanish continental Neogene display four relative temperature peaks indicative of warm c1imatic conditions (Late Agenian, Early-Middle Aragonian, Vallesian-Turolian, and Late Villafranchian) as well as five relatively dry periods (Early Ramblian, Middle-Late Aragonian, Middle Turolian, Late Ruscinian, and Middle Villafranchian ages)