The effect of Agaricus blazei Murill on haematological parameter, random blood sugar, total cholesterol, and uric acid of wistar rats (Sprague Dawley)

Agaricus blazei Murill (ABM) has traditionally been used as a prevention and cure of several diseases, such as cancer, diabetes, hypertension, immunostimulant, due to its contents such as 1,3-β-D-Glucan, ergosterol, agaritine, tocoferolum, scorbic acid, terpenes. This study is carried out in order to uncover which doses of ABM powder treatment, classified as suitable doses for a healthy condition of experimental animals based on hematological parameters (haemoglobin, erytrocyt, and leucocyt), random blood sugar, cholesterol, and uric acid. This study was an experimental study using experimental animals (rats) treated with ABM powders (three doses) and pure compounds of 1,3-β-DGlucan compared to the control group. Based on all parameter studied, it can be concluded that ABM consumption of 7.2 mg is the most suitable one of dose to be recomended for healthy condition

Anticancer and antioxidant Holuthuria edulis

This research describes the antioxidant and anticancer activity of sea cucumber extract Holothuria edulis from Labuan Bajo. Sea cucumbers are extracted using three methods, namely maceration, soxhletation and ultrasonication. The data displayed is related to the calculation of toxicity data for the BSLT method, antioxidants and anticancer MCF-7 cells.The BSLT method toxicity calculation is as follows, the calculation of toxicity (IC50) was carried out using probit analysis. Number of dead larvae% death = ------------------------ x 100%Number of test larvaeThe IC50 was then calculatedA blank – A sample% inhibition = -------------------- x 100%A blankThe IC50 was then calculated: The absorbance of treated cells – absorbance of control media% cell death = -------------------------------------------------------------------- x 100% The absorbance of control cell – Absorbance of control mediaTHIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOV