293 research outputs found
User guide for the British Geological Survey National Depth to Groundwater Dataset
This report presents a description and review of the methodology developed by the British geological Survey (BGS) to produce a national scale dataset of depth to groundwater. The method has been critically assessed and its fitness for purpose determined by scientists who specialise in hydrogeology at BGS. The purpose of this user guide is to enable those licensing this dataset to have a better appreciation of how the dataset has been created and therefore better understand the potential applications and limitations that the dataset may have
Estimating numbers of properties susceptible to groundwater flooding in England
In the wake of widespread groundwater flooding that affected properties and infrastructure in southern England during 2014, a review has been undertaken of the number of properties in England that might be vulnerable during episodes of high groundwater levels, and an estimate made of how many properties might be affected in susceptible areas.
Groundwater flooding can happen in many geological environments, but is a particular problem on Chalk and Limestone aquifers, where around 920,000 properties are in areas where groundwater emergence could occur. This represents fewer properties than previously estimated for these areas. However, a further 3,800,000 properties are in areas underlain by other aquifer types that could be affected by groundwater flooding or shallow water tables.
The actual impact of groundwater flooding on properties is often mitigated by building design or natural/artificial drainage systems which act to lower water tables and move emergent water to rivers. As a result only a small percentage of properties identified above are likely to be impacted by groundwater flooding. Although there is limited observational data, we believe that up to 138,000 properties might be impacted in chalk and limestone areas and up to 151,600 in other areas.
This means the revised estimate of the number of properties in areas at risk of groundwater flooding is between 122,000 and 290,000.
Groundwater may play a role in the flooding of a further 980,000 properties in areas that are also at risk from river and/or coastal flooding. In addition, groundwater flooding is a significant issue for subsurface infrastructure. Note that this latter issue has not been assessed in this report
Giant positive magnetoresistance in metallic VOx thin films
We report on giant positive magnetoresistance effect observed in VOx thin
films, epitaxially grown on SrTiO3 substrate. The MR effect depends strongly on
temperature and oxygen content and is anisotropic. At low temperatures its
magnitude reaches 70% in a magnetic field of 5 T. Strong electron-electron
interactions in the presence of strong disorder may qualitatively explain the
results. An alternative explanation, related to a possible magnetic
instability, is also discussed.Comment: 4 pages, 5 figures included in the text, references update
Cosmic-ray acceleration in supernova remnants: non-linear theory revised
A rapidly growing amount of evidences, mostly coming from the recent
gamma-ray observations of Galactic supernova remnants (SNRs), is seriously
challenging our understanding of how particles are accelerated at fast shocks.
The cosmic-ray (CR) spectra required to account for the observed phenomenology
are in fact as steep as , i.e., steeper than the
test-particle prediction of first-order Fermi acceleration, and significantly
steeper than what expected in a more refined non-linear theory of diffusive
shock acceleration. By accounting for the dynamical back-reaction of the
non-thermal particles, such a theory in fact predicts that the more efficient
the particle acceleration, the flatter the CR spectrum. In this work we put
forward a self-consistent scenario in which the account for the magnetic field
amplification induced by CR streaming produces the conditions for reversing
such a trend, allowing --- at the same time --- for rather steep spectra and CR
acceleration efficiencies (about 20%) consistent with the hypothesis that SNRs
are the sources of Galactic CRs. In particular, we quantitatively work out the
details of instantaneous and cumulative CR spectra during the evolution of a
typical SNR, also stressing the implications of the observed levels of
magnetization on both the expected maximum energy and the predicted CR
acceleration efficiency. The latter naturally turns out to saturate around
10-30%, almost independently of the fraction of particles injected into the
acceleration process as long as this fraction is larger than about .Comment: 24 pages, 5 figures, accepted for publication in JCA
The Dependence of the Superconducting Transition Temperature of Organic Molecular Crystals on Intrinsically Non-Magnetic Disorder: a Signature of either Unconventional Superconductivity or Novel Local Magnetic Moment Formation
We give a theoretical analysis of published experimental studies of the
effects of impurities and disorder on the superconducting transition
temperature, T_c, of the organic molecular crystals kappa-ET_2X and beta-ET_2X
(where ET is bis(ethylenedithio)tetrathiafulvalene and X is an anion eg I_3).
The Abrikosov-Gorkov (AG) formula describes the suppression of T_c both by
magnetic impurities in singlet superconductors, including s-wave
superconductors and by non-magnetic impurities in a non-s-wave superconductor.
We show that various sources of disorder lead to the suppression of T_c as
described by the AG formula. This is confirmed by the excellent fit to the
data, the fact that these materials are in the clean limit and the excellent
agreement between the value of the interlayer hopping integral, t_perp,
calculated from this fit and the value of t_perp found from angular-dependant
magnetoresistance and quantum oscillation experiments. If the disorder is, as
seems most likely, non-magnetic then the pairing state cannot be s-wave. We
show that the cooling rate dependence of the magnetisation is inconsistent with
paramagnetic impurities. Triplet pairing is ruled out by several experiments.
If the disorder is non-magnetic then this implies that l>=2, in which case
Occam's razor suggests that d-wave pairing is realised. Given the proximity of
these materials to an antiferromagnetic Mott transition, it is possible that
the disorder leads to the formation of local magnetic moments via some novel
mechanism. Thus we conclude that either kappa-ET_2X and beta-ET_2X are d-wave
superconductors or else they display a novel mechanism for the formation of
localised moments. We suggest systematic experiments to differentiate between
these scenarios.Comment: 18 pages, 5 figure
3D MHD Flux Emergence Experiments: Idealized models and coronal interactions
This paper reviews some of the many 3D numerical experiments of the emergence
of magnetic fields from the solar interior and the subsequent interaction with
the pre-existing coronal magnetic field. The models described here are
idealized, in the sense that the internal energy equation only involves the
adiabatic, Ohmic and viscous shock heating terms. However, provided the main
aim is to investigate the dynamical evolution, this is adequate. Many
interesting observational phenomena are explained by these models in a
self-consistent manner.Comment: Review article, accepted for publication in Solar Physic
Extension to order of the high-temperature expansions for the spin-1/2 Ising model on the simple-cubic and the body-centered-cubic lattices
Using a renormalized linked-cluster-expansion method, we have extended to
order the high-temperature series for the susceptibility
and the second-moment correlation length of the spin-1/2 Ising models on
the sc and the bcc lattices. A study of these expansions yields updated direct
estimates of universal parameters, such as exponents and amplitude ratios,
which characterize the critical behavior of and . Our best
estimates for the inverse critical temperatures are
and . For the
susceptibility exponent we get and for the correlation
length exponent we get .
The ratio of the critical amplitudes of above and below the critical
temperature is estimated to be . The analogous ratio for
is estimated to be . For the correction-to-scaling
amplitude ratio we obtain .Comment: Misprints corrected, 8 pages, latex, no figure
Origins of the Ambient Solar Wind: Implications for Space Weather
The Sun's outer atmosphere is heated to temperatures of millions of degrees,
and solar plasma flows out into interplanetary space at supersonic speeds. This
paper reviews our current understanding of these interrelated problems: coronal
heating and the acceleration of the ambient solar wind. We also discuss where
the community stands in its ability to forecast how variations in the solar
wind (i.e., fast and slow wind streams) impact the Earth. Although the last few
decades have seen significant progress in observations and modeling, we still
do not have a complete understanding of the relevant physical processes, nor do
we have a quantitatively precise census of which coronal structures contribute
to specific types of solar wind. Fast streams are known to be connected to the
central regions of large coronal holes. Slow streams, however, appear to come
from a wide range of sources, including streamers, pseudostreamers, coronal
loops, active regions, and coronal hole boundaries. Complicating our
understanding even more is the fact that processes such as turbulence,
stream-stream interactions, and Coulomb collisions can make it difficult to
unambiguously map a parcel measured at 1 AU back down to its coronal source. We
also review recent progress -- in theoretical modeling, observational data
analysis, and forecasting techniques that sit at the interface between data and
theory -- that gives us hope that the above problems are indeed solvable.Comment: Accepted for publication in Space Science Reviews. Special issue
connected with a 2016 ISSI workshop on "The Scientific Foundations of Space
Weather." 44 pages, 9 figure
Orbital effect of a magnetic field on the low temperature state in the organic metal -(BEDT-TTF)KHg(SCN)
The effect of pressure on the B--T phase diagram of
-(BEDT-TTF)KHg(SCN) is studied. The measured phase lines can be
well described by a recent model of a charge-density wave system with varying
nesting conditions. A remarkable increase of the transition temperature with
magnetic field is found in a certain pressure and field range. We associate
this result with a dramatic enhancement of the orbital effect of magnetic field
due to a deterioration of the nesting conditions by pressure. Furthermore, we
present data which can be interpreted as a first sign of field-induced
charge-density waves.Comment: 9 pages, 5 figure
Enhanced neutrophil extracellular trap formation in COVID-19 is inhibited by the protein kinase C inhibitor ruboxistaurin
Background: Neutrophil extracellular traps (NETs) are web-like DNA and protein lattices which are expelled by neutrophils to trap and kill pathogens, but which cause significant damage to the host tissue. NETs have emerged as critical mediators of lung damage, inflammation and thrombosis in coronavirus disease 2019 (COVID-19) and other diseases, but there are no therapeutics to prevent or reduce NETs that are available to patients.
Methods: Neutrophils were isolated from healthy volunteers (n=9) and hospitalised patients with COVID-19 at the acute stage (n=39) and again at 3–4 months post-acute sampling (n=7). NETosis was measured by SYTOX green assays.
Results: Here, we show that neutrophils isolated from hospitalised patients with COVID-19 produce significantly more NETs in response to lipopolysaccharide (LPS) compared to cells from healthy control subjects. A subset of patients was captured at follow-up clinics (3–4 months post-acute sampling), and while LPS-induced NET formation is significantly lower at this time point, it remains elevated compared to healthy controls. LPS- and phorbol myristate acetate (PMA)-induced NETs were significantly inhibited by the protein kinase C (PKC) inhibitor ruboxistaurin. Ruboxistaurin-mediated inhibition of NETs in healthy neutrophils reduces NET-induced epithelial cell death.
Conclusion: Our findings suggest ruboxistaurin could reduce proinflammatory and tissue-damaging consequences of neutrophils during disease, and since it has completed phase III trials for other indications without safety concerns, it is a promising and novel therapeutic strategy for COVID-19
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