A Mixed Methods Study of the Relationships among Academic Achievement, Teaching Strategies and Science and Engineering Fair Participation

It has long been accepted by science education research that science inquiry in the classroom is essential to the development of a deep understanding of the nature of science and the world around us. In an effort to understand the relationship between science inquiry, science process skills, the nature of science and science and engineering fairs, this mixed methods study qualitatively explores teaching strategies of exemplary science and engineering teachers (N=6) who mentored several International Science and Engineering Fair finalists within a 10 year period (2004-2014). The quantitative portion of this research explored the relationship between science fair participation and academic achievement. Using the theoretical framework of modern expectancy-value theory, 5 themes emerged. All believed: 1) there is intrinsic value in science inquiry and science fair; 2) all included strategic engagement opportunities for students; 3) intrinsic value and motivation potentially lead to increased academic aptitude; 4) the benefits of science inquiry and science fair outweigh costs; and 5) there is a link between intrinsic value in science and engineering fair and utility value. Of the schools (N=31) identified for the quantitative study, demographic analysis (gender, ethnicity, socio-economic statics, and size of school) narrowed to 8 treatment schools with one control school indicated no statistical relationship between academic performance on a standardized state science examination and science fair participation. An ad hoc study indicated the standardized testing instrument was not an adequate measurement of the level of inquiry included in a science and engineering fair project. In conclusion, a list comprised of exemplary science and engineering fair suggestions was formulated to include descriptions of similar teaching strategies or issues among the exemplary science and engineering fair teachers with intentions of increasing science inquiry or the nature of science in the classroom through the science and engineering fair framework

Bringing Math to Life: Provide Students Opportunities to Connect their Lives to Math

Math journals provide students with opportunities to articulate their understanding of math concepts and/or their frustrations with the gaps in those understandings. Their use supports metacognitive thinking to enhance understanding and application. This study took a look at the use of math journals by fourth grade students as a conduit for critical thinking, reflection, and real world math application. For this study, student journal entries consisted of identification of a real-life event, the use of a problem-solving strategy learned during class instruction, narrative of both the problem’s description as well as the rationale for choosing the problem, and the use of a numeric or pictorial model with solution. Students shared his/her journal entry with the entire class. Through this research, I witnessed evidence of growth in mathematical understanding, computing and a deeper connection to math’s many real-life applications in the lives of elementary students

Addressing the Gap of Informal Science Field Experiences in Science Methods Courses

Preservice teachers in science education courses do not generally experience informal, authentic science education practices in their fieldwork. This study used the Scholarship of Teaching and Learning to frame a study that integrated informal science teaching experiences with a university teacher education science methods course. The results showed improvement in participant preservice teachers\u27 ability to teach science content, their self-confidence in teaching science, and their ability to connect what they learned in their methods course in a real-life setting

Racial Disparities in Childhood Asthma in the United States: Evidence From the National Health Interview Survey, 1997 to 2003

Objective: To examine differences in asthma prevalence and emergency department (ED) visits for asthma between non-Hispanic black and white children, and factors that might explain those differences, in a large, nationally representative sample covering the period 1997 to 2003. Methods: Bivariate and multivariate regression analyses (with logit and multinomial logit methods) were conducted with a sample consisting of all non-Hispanic black and white children (< 18 years of age) from the 1997 to 2003 rounds of the National Health Interview Survey. Models included a progressively larger set of controls for factors that might explain racial differences in asthma prevalence and ED visits for asthma. Results: Being black was associated with a greater likelihood of currently having asthma and with a greater likelihood of having gone to the ED for asthma treatment in the past 1 year. Elevated asthma risks for black children were robust after controlling for a host of child and family characteristics that might explain them. Conclusions: Black children are more likely to have asthma and to experience ED visits for asthma, compared with otherwise comparable white children, and these racial disparities cannot be explained by differences in measurable child or family characteristics. These results suggest that racial disparities in asthma continue to pose risks for black children, and they point to the need for additional research into potential explanations and remedies

Rethinking the Core List of Journals for Libraries that Serve Schools and Colleges of Pharmacy.

The Core List of Journals for Libraries that Serve Schools and Colleges of Pharmacy is a guide for developing and maintaining pharmacy-affiliated library collections. A work group was created to update the list and design a process for updating that will streamline future revisions. Work group members searched the National Library of Medicine catalog for an initial list of journals and then applied inclusion criteria to narrow the list. The work group finalized the fifth edition of the list with 225 diverse publications and produced a sustainable set of criteria for journal inclusion, providing a structured, objective process for future updates

A Different Kind of Kid, A Different Kind of Teacher Education: Middle Grades Teachers Reflect on Their Preparation to Teach Young Adolescents

Good teaching at the middle grades comes out of a deep understanding of the unique cognitive, physical, social, emotional, and moral needs of young adolescents. Therefore specialized preparation is necessary to help teacher candidates understand how to operationalize the intersection of young adolescent development and the effective pedagogy that addresses their needs. This paper focuses on a qualitative study of experienced middle school teachers who graduated from a middle level preparation program or an elementary or secondary preparation program in terms of how well prepared they felt and feel to meet the widely varied needs of young adolescents. Confidence in preparation leads to high self-efficacy, which is important for perseverance and effectiveness. Graduates of a middle level preparation program reported higher levels of confidence in their preparation to teach young adolescents

Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae

The benzylisoquinoline alkaloids (BIAs) are a diverse class of metabolites that exhibit a broad range of pharmacological activities and are synthesized through plant biosynthetic pathways comprised of complex enzyme activities and regulatory strategies. We have engineered yeast to produce the key intermediate reticuline and downstream BIA metabolites from a commercially available substrate. An enzyme tuning strategy was implemented that identified activity differences between variants from different plants and determined optimal expression levels. By synthesizing both stereoisomer forms of reticuline and integrating enzyme activities from three plant sources and humans, we demonstrated the synthesis of metabolites in the sanguinarine/berberine and morphinan branches. We also demonstrated that a human P450 enzyme exhibits a novel activity in the conversion of (R)-reticuline to the morphinan alkaloid salutaridine. Our engineered microbial hosts offer access to a rich group of BIA molecules and associated activities that will be further expanded through synthetic chemistry and biology approaches

Diagnosis, Treatment and Follow Up of Acute Pulmonary Embolism: Consensus Practice from the PERT Consortium

Pulmonary embolism (PE) is a life-threatening condition and a leading cause of morbidity and mortality. There have been many advances in the field of PE in the last few years, requiring a careful assessment of their impact on patient care. However, variations in recommendations by different clinical guidelines, as well as lack of robust clinical trials, make clinical decisions challenging. The Pulmonary Embolism Response Team Consortium is an international association created to advance the diagnosis, treatment, and outcomes of patients with PE. In this consensus practice document, we provide a comprehensive review of the diagnosis, treatment, and follow-up of acute PE, including both clinical data and consensus opinion to provide guidance for clinicians caring for these patients

Analysis of a viral metagenomic library from 200 m depth in Monterey Bay, California constructed by direct shotgun cloning

<p>Abstract</p> <p>Background</p> <p>Viruses have a profound influence on both the ecology and evolution of marine plankton, but the genetic diversity of viral assemblages, particularly those in deeper ocean waters, remains poorly described. Here we report on the construction and analysis of a viral metagenome prepared from below the euphotic zone in a temperate, eutrophic bay of coastal California.</p> <p>Methods</p> <p>We purified viruses from approximately one cubic meter of seawater collected from 200m depth in Monterey Bay, CA. DNA was extracted from the virus fraction, sheared, and cloned with no prior amplification into a plasmid vector and propagated in <it>E. coli </it>to produce the MBv200m library. Random clones were sequenced by the Sanger method. Sequences were assembled then compared to sequences in GenBank and to other viral metagenomic libraries using BLAST analyses.</p> <p>Results</p> <p>Only 26% of the 881 sequences remaining after assembly had significant (E ≤ 0.001) BLAST hits to sequences in the GenBank nr database, with most being matches to bacteria (15%) and viruses (8%). When BLAST analysis included environmental sequences, 74% of sequences in the MBv200m library had a significant match. Most of these hits (70%) were to microbial metagenome sequences and only 0.7% were to sequences from viral metagenomes. Of the 121 sequences with a significant hit to a known virus, 94% matched bacteriophages (Families <it>Podo</it>-, <it>Sipho</it>-, and <it>Myoviridae</it>) and 6% matched viruses of eukaryotes in the Family <it>Phycodnaviridae </it>(5 sequences) or the Mimivirus (2 sequences). The largest percentages of hits to viral genes of known function were to those involved in DNA modification (25%) or structural genes (17%). Based on reciprocal BLAST analyses, the MBv200m library appeared to be most similar to viral metagenomes from two other bays and least similar to a viral metagenome from the Arctic Ocean.</p> <p>Conclusions</p> <p>Direct cloning of DNA from diverse marine viruses was feasible and resulted in a distribution of virus types and functional genes at depth that differed in detail, but were broadly similar to those found in surface marine waters. Targeted viral analyses are useful for identifying those components of the greater marine metagenome that circulate in the subcellular size fraction.</p