The particularity of emotional words. A grounded approach

This work focuses on emotional concepts. We define concepts as patterns of neural activation that re-enact a given external or internal experience, for example the interoceptive experience related to fear. Concepts are mediated and expressed through words. In the following, we will use “words” to refer to word meanings, assuming that words mediate underlying concepts. Since emotional concepts and the words that mediate them are less related to the physical environment than concrete ones, at first sight they might be depicted as abstract concepts. Evidence coming from several studies shows, instead, that the issue is more complex. In this work, we will briefly outline the debate and illustrate results from recent studies on comprehension of concrete, emotional and abstract words in children and adults. We will argue that emotional words can be accounted for from a grounded perspective and will contend that emotional words represent a particular set of words that differs from both the concrete and purely abstract ones

Star formation in the central regions of galaxies

Massive star formation in the central regions of spiral galaxies plays an important role in the dynamical and secular evolution of their hosts. Here, we summarise a number of recent investigations of the star formation history and the physical conditions of the gas in circumnuclear regions, to illustrate not only the detailed results one can achieve, but also the potential of using state-of-the-art spectroscopic and analysis techniques in researching the central regions of galaxies in general. We review how the star formation history of nuclear rings confirms that they are long-lived and stable configurations. Gas flows in from the disk, through the bar, and into the ring, where successive episodes of massive star formation occur. Analysing the ring in NGC 7742 in particular, we determine the physical conditions of the line emitting gas using a combination of ionisation and stellar population modelling, concluding that the origin of the nuclear ring in this non-barred galaxy lies in a recent minor merger with a small gas-rich galaxy.Comment: Invited contribution, to appear in "Mapping the Galaxy and other galaxies", Eds. K. Wada and F. Combes, Springer, in pres

Gender is conceptualized in different ways across cultures

Gender can be considered an embodied social concept encompassing biological and cultural components. In this study, we explored whether the concept of gender varies as a function of different cultural and linguistic norms by comparing communities that vary in their social treatment of gender-related issues and linguistic encoding of gender. In Study 1, Italian, Dutch, and English-speaking participants completed a free-listing task, which showed Italians and Dutch were the most distinct in their conceptualization of gender: Italian participants focused more on socio-cultural features (e.g., discrimination, politics, and power), whereas Dutch participants focused more on the corporeal sphere (e.g., hormones, breasts, and genitals). Study 2 replicated this finding focusing on Italian and Dutch and using a typicality rating task: socio-cultural and abstract features were considered as more typical of "gender"by Italian than Dutch participants. Study 3 addressed Italian and Dutch participants' explicit beliefs about gender with a questionnaire measuring essentialism and constructivism, and consolidated results from Studies 1 and 2 showing that Dutch participants endorsed more essentialist beliefs about gender than Italian participants. Consistent with socio-cultural constructivist accounts, our results provide evidence that gender is conceptualized differently by diverse groups and is adapted to specific cultural and linguistic environments

Toward a reversible consolidation of paper materials using cellulose nanocrystals

An innovative consolidation strategy for degraded paper is presented based on the reversible application of cellulose nanocrystals as sustainable fillers to reinforce mechanical properties and resistance to further degradation. The compatibility and efficacy of the proposed consolidation treatment are assessed first on pure cellulose paper, used as a model, by reliable techniques such as field emission scanning electron microscopy, atomic force microscopy, tensile tests, X-ray powder diffraction, and Fourier transform infrared spectroscopy, evidencing the influence of the surface functionalization of nanocellulose on the consolidation and protection effects. Then, the consolidation technique is applied to real aged paper samples fromBreviarium romanum ad usum Fratrum Minorum S.P.(1738), demonstrating the promising potential of the suggested approach. Amperometric measurements, carried out with a smart electrochemical tool developed in our laboratory, demonstrate the reversibility of the proposed treatment by removal of the nanocrystalline cellulose from the paper surface with a suitable cleaning hydrogel. This completely new feature of the consolidation treatment proposed here satisfies a pivotal requisite in cultural heritage conservation because the methodological requirement for the ″reversibility″ of any conservation measure is a fundamental goal for restorers. A paper artifact, in fact, is subject to a number of natural and man-made hazards, inducing continuous degradation. With time, monitoring and consolidation actions need to be often performed to ensure conservation, and this tends to modify the status quo and compromise the artifact integrity. Removable treatments can potentially avoid erosion of the artifact integrity

Drug–drug interactions and pharmacogenomic evaluation in colorectal cancer patients. The new drug-pin® system comprehensive approach

Drug–drug interactions (DDIs) can affect both treatment efficacy and toxicity. We used Drug-PIN® (Personalized Interactions Network) software in colorectal cancer (CRC) patients to evaluate drug–drug–gene interactions (DDGIs), defined as the combination of DDIs and individual genetic polymorphisms. Inclusion criteria were: (i) stage II-IV CRC; (ii) ECOG PS (Performance status sec. Eastern coperative oncology group) ≤2; (iii) ≥5 concomitant drugs; and (iv) adequate renal, hepatic, and bone marrow function. The Drug-PIN® system analyzes interactions between active and/or pro-drug forms by integrating biochemical, demographic, and genomic data from 110 SNPs. We selected DDI, DrugPin1, and DrugPin2 scores, resulting from concomitant medication interactions, concomitant medications, and SNP profiles, and DrugPin1 added to chemotherapy drugs, respectively. Thirty-four patients, taking a median of seven concomitant medications, were included. The median DrugPin1 and DrugPin2 scores were 42.6 and 77.7, respectively. In 13 patients, the DrugPin2 score was two-fold higher than the DrugPin1 score, with 7 (54%) of these patients experiencing severe toxicity that required hospitalization. On chi-squared testing for any toxic-ity, a doubled DrugPin2 score (p = 0.001) was significantly related to G3–G4 toxicity. Drug-PIN® software may prevent severe adverse events, decrease hospitalizations, and improve survival in cancer patients

A hydroalcoholic gel-based disinfection system for deteriogenic fungi on the contemporary mixed media artwork Poesia by Alessandro Kokocinski

The disinfection of deteriogenic microorganisms and the removal of induced chromatic alterations in artworks are still open challenges in the field of conservation. For this purpose, a new alcoholic hydrogel was tested to remove an extensive fungal attack from a multimaterial collage by the artist Alessandro Kokocinski and to mitigate chromatic changes caused by the contamination of its poster paper and plywood support layers. A Gellan gum-based hydrogel was used, which was modified by adding a high concentration of alcohol (66.7% ethanol), to give the system an effective disinfecting agent in addition to the detergent capacity of the gel for water-sensitive works of art. It was successfully tested on samples mimicking the complex stratigraphy of the artwork under study. To create replica mock-ups, the artwork materials and stratigraphy were investigated through diagnostic and laboratory techniques such as multispectral imaging, X-ray fluorescence spectroscopy, Fourier transform infrared spectroscopy, and pyrolysis coupled with gas-chromatography-mass spectrometry. The treatment was shown to have a disinfecting effect on the test samples and did not alter their structure, allowing us to apply the method to the artwork. Here, the hydrogel successfully removed and inhibited fungal proliferation in addition to mitigating the color changes caused by fungi

Gellan hydrogel as a powerful tool in paper cleaning process: a detailed study

Hypothesis: Wet cleaning of ancient papers is one of the most critical steps during a conservation treatment. It is used to improve the optical qualities of a graphic work and remove dust and by-products resulting from cellulose degradation. Nevertheless, washing treatment usually involves a substantial impact on the original morphological structure of paper and can sometimes be dangerous for water sensitive inks and pigments. Experiments: The use of rigid hydrogel of Gellan gum as an alternative paper cleaning treatment is developed. The application of a rigid hydrogel minimizes damages caused by the use of water, and therefore is much more respectful for the original integrity of ancient paper. Findings: Gellan hydrogel has been used to clean paper samples belonging to different centuries (from XVI to XIX) and therefore, characterized by a different story in terms of degradation condition and paper composition. Several techniques, such as high-performance liquid chromatography, Fourier transform infrared spectroscopy, scanning electron microscopy and pH measurements, has been employed to assess the effectiveness and safety of the proposed cleaning method

A Connection between Star Formation in Nuclear Rings and their Host Galaxies

We present results from a photometric H-alpha survey of 22 nuclear rings, aiming to provide insight into their star formation properties, including age distribution, dynamical timescales, star formation rates, and galactic bar influence. We find a clear relationship between the position angles and ellipticities of the rings and those of their host galaxies, which indicates the rings are in the same plane as the disk and circular. We use population synthesis models to estimate ages of each H-alpha emitting HII region, which range from 1 Myr to 10 Myrs throughout the rings. We find that approximately half of the rings contain azimuthal age gradients that encompass at least 25% of the ring, although there is no apparent relationship between the presence or absence of age gradients and the morphology of the rings or their host galaxies. NGC1343, NGC1530, and NGC4321 show clear bipolar age gradients, where the youngest HII regions are located near the two contact points of the bar and ring. We speculate in these cases that the gradients are related to an increased mass inflow rate and/or an overall higher gas density in the ring, which would allow for massive star formation to occur on short timescales, after which the galactic rotation would transport the HII regions around the ring as they age. Two-thirds of the barred galaxies show correlation between the locations of the youngest HII region(s) in the ring and the location of the contact points, which is consistent with predictions from numerical modeling.Comment: 23 pages, 10 figures (7 color), 23 tables, accepted for publication in ApJS (Feb 08); NASA-GSFC, IAC, University of Maryland, STSc