16,543 research outputs found
An approach to market analysis for lighter than air transportation of freight
An approach is presented to marketing analysis for lighter than air vehicles in a commercial freight market. After a discussion of key characteristics of supply and demand factors, a three-phase approach to marketing analysis is described. The existing transportation systems are quantitatively defined and possible roles for lighter than air vehicles within this framework are postulated. The marketing analysis views the situation from the perspective of both the shipper and the carrier. A demand for freight service is assumed and the resulting supply characteristics are determined. Then, these supply characteristics are used to establish the demand for competing modes. The process is then iterated to arrive at the market solution
Lifetimes and Gj factors in excited states of chromium. Hyperfine structure of Cr53
Electronic and nuclear properties of excited chromium isotopes using level crossing and double resonance spectroscopy technique
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Vitamin B12 measurements across neurodegenerative disorders.
Background:Vitamin B12 deficiency causes a number of neurological features including cognitive and psychiatric disturbances, gait instability, neuropathy, and autonomic dysfunction. Clinical recognition of B12 deficiency in neurodegenerative disorders is more challenging because it causes defects that overlap with expected disease progression. We sought to determine whether B12 levels at the time of diagnosis in patients with Parkinson's disease (PD) differed from those in patients with other neurodegenerative disorders. Methods:We performed a cross-sectional analysis of B12 levels obtained around the time of diagnosis in patients with PD, Multiple System Atrophy (MSA), Dementia with Lewy Bodies (DLB), Alzheimer's disease (AD), Progressive Supranuclear Palsy (PSP), Frontotemporal Dementia (FTD), or Mild Cognitive Impairment (MCI). We also evaluated the rate of B12 decline in PD, AD, and MCI. Results:In multivariable analysis adjusted for age, sex, and B12 supplementation, we found that B12 levels were significantly lower at time of diagnosis in patients with PD than in patients with PSP, FTD, and DLB. In PD, AD, and MCI, the rate of B12 decline ranged from - 17 to - 47 pg/ml/year, much greater than that reported for the elderly population. Conclusions:Further studies are needed to determine whether comorbid B12 deficiency affects progression of these disorders
A High Reliability Asymptotic Approach for Packet Inter-Delivery Time Optimization in Cyber-Physical Systems
In cyber-physical systems such as automobiles, measurement data from sensor
nodes should be delivered to other consumer nodes such as actuators in a
regular fashion. But, in practical systems over unreliable media such as
wireless, it is a significant challenge to guarantee small enough
inter-delivery times for different clients with heterogeneous channel
conditions and inter-delivery requirements. In this paper, we design scheduling
policies aiming at satisfying the inter-delivery requirements of such clients.
We formulate the problem as a risk-sensitive Markov Decision Process (MDP).
Although the resulting problem involves an infinite state space, we first prove
that there is an equivalent MDP involving only a finite number of states. Then
we prove the existence of a stationary optimal policy and establish an
algorithm to compute it in a finite number of steps.
However, the bane of this and many similar problems is the resulting
complexity, and, in an attempt to make fundamental progress, we further propose
a new high reliability asymptotic approach. In essence, this approach considers
the scenario when the channel failure probabilities for different clients are
of the same order, and asymptotically approach zero. We thus proceed to
determine the asymptotically optimal policy: in a two-client scenario, we show
that the asymptotically optimal policy is a "modified least time-to-go" policy,
which is intuitively appealing and easily implementable; in the general
multi-client scenario, we are led to an SN policy, and we develop an algorithm
of low computational complexity to obtain it. Simulation results show that the
resulting policies perform well even in the pre-asymptotic regime with moderate
failure probabilities
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