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Exposures to aflatoxin B₁, paraquat, cadmium chloride and 6-OHDA caused detectable DNA damage.

<p>p<.0001, p<.0001, p = 0.028, p<.0001 respectively for main effects of dose. Aflatoxin B₁, paraquat and cadmium chloride caused more damage to the mitochondrial than nuclear genomes (p<.0001, p<.0001, and p = 0.0125 respectively for main effect of genome). Data analyzed by Two-way ANOVA. Bars ± SEM.</p

Representation of progressive damage in dopaminergic neurons after 6-OHDA exposure.

<p>The circled areas include typically observed abnormalities, referred to as blebs and breaks in this publication.</p