Film holder for curved vacuum platen

Vacuum apparatus for holding photographic film of various widths against cylindrically curved patens is discussed. Construction details and method of operation are explained. Illustration of equipment is provided

New freshwater sponges from Amazonian waters

Four species of freshwater sponges have their first register of occurrence for Amazonian waters upon specimens collected from Culuene and Sete de Setembro Rivers (Xingú basin), Tapirapés River (Araguaia basin) and Cuieiras River. Trochospongilla pennsylvanica (POTTS 1882) and Trochospongilla variabilis BONETTO & EZCURRA DE DRAGO (1973) occurred as minute specimens inside large sponges of the genus Metania GRAY (1867) or of the genus Drulia GRAY (1867). T. pennsylvanica has its first register of occurrence for the Neotropical region. Spongilla spoliata n. sp. resembles Spongilla inarmata ANNADALE (1918) and Spongilla aspinosa POTTS (1880) but is readily separated from these two species on account of the characteristic spines on its microscleres. Radiospongilla amazonensis n. sp. differs from its congeners by the particular characteristics of its megascleres and gemmoscleres

Alignment microscope for rotating laser scanner

Microscopic assembly for alignment of rotary laser focuses on small film area along scan line at oblique angle. Suitable choice of angle and location of optical components project laser beam line as X coordinate reticle. Coordination with horizontal recticle line included microscope facilitates Y coordinate position indexing

The Electron Temperature Gradient in the Galactic Disk

We derive the electron temperature gradient in the Galactic disk using a sample of HII regions that spans Galactocentric distances 0--17 kpc. The electron temperature was calculated using high precision radio recombination line and continuum observations for more than 100 HII regions. Nebular Galactocentric distances were calculated in a consistent manner using the radial velocities measured by our radio recombination line survey. The large number of nebulae widely distributed over the Galactic disk together with the uniformity of our data provide a secure estimate of the present electron temperature gradient in the Milky Way. Because metals are the main coolants in the photoionized gas, the electron temperature along the Galactic disk should be directly related to the distribution of heavy elements in the Milky Way. Our best estimate of the electron temperature gradient is derived from a sample of 76 sources for which we have the highest quality data. The present gradient in electron temperature has a minimum at the Galactic Center and rises at a rate of 287 +/- 46 K/kpc. There are no significant variations in the value of the gradient as a function of Galactocentric radius or azimuth. The scatter we find in the HII region electron temperatures at a given Galactocentric radius is not due to observational error, but rather to intrinsic fluctuations in these temperatures which are almost certainly due to fluctuations in the nebular heavy element abundances. Comparing the HII region gradient with the much steeper gradient found for planetary nebulae suggests that the electron temperature gradient evolves with time, becoming flatter as a consequence of the chemical evolution of the Milky Way's disk.Comment: 43 pages, 9 figures (accepted for publication in the ApJ

Molecular genetics of intellectual disability

The goal of this chapter is to review the current knowledge of the genetic causes of intellectual disability, focusing on alterations at the chromosomal and single gene level, with particular mention to the new technological developments, including array technologies and next-generation sequencing, which allowed an enormous increase in yield from genetic studies. The cellular and physiological pathways that seem to be most affected in intellectual disability will also be addressed. Finally, a brief analysis of the contribution of the genetically modified animal models for the study of the pathogenesis of intellectual disability and for the development and testing of novel therapeutic approaches, with unexpectedly good results, previously thought to be impossible to achieve. The chapter will close with some considerations on the relevance and future perspectives of genetic testing in patients with intellectual disability