Production of cytokines at the operation site

Background and aim: Cytokines are part of a family of molecules involved in the initiation, control and termination of the events that occurs in wound healing process. Aim of this study was to evaluate the production of some cytokines [interleukin (IL)-6, IL-10, IL-1a, IL-1ra, interferon (IFN)-g] in the drainage wound fluid from patients undergoing incisional hernia repair. Methods: Ten female patients with abdominal midline incisional hernia undergoing to surgical repair were included in this study. In all cases a closed suction drain was placed in the wound below the fascia and it was removed on the 4 th postoperative day. Wound fluid was collected on the 1st , 2 nd, 3rd and 4th day and its amount in each time was recorded. The production of IL-6, IL-10, IL-1a, IL-1ra and IFN-g were evaluated as quantity produced in 24 hour. Results: In all patients the amount of drain fluid from surgical wound was highest on the 1st day after surgery, afterwards there is a significant reduction. The production of all cytokines evaluated was highest on the 1st day decreasing on the 2nd day except for IL-1a that not show any modification. The produciton of IL-1ra, IL-6, IL-1a and IL-10 was significantly reduced on the 3rd and 4th postoperative day in comparison with the respectively values recorded on the 1st day, whereas IFN-g levels were similar. Conclusions: The dosage of cytokines in the drain fluid led us to better evaluated the events that follow surgical wound and their analysis offers further information in the role of cytokines in healing process, with the goal to get supportive treatments to promote the best evolution

Using Small Unmanned Aircraft Systems for Remote Sensing and Data Collection: Aerospace Education and Service Learning

The authors conducted a service learning study abroad with 23 students in the Balkan country, Republic of Kosovo, during June and July 2019. Students came from the College of Aviation and Engineering and were enrolled in undergraduate coursework. Using small unmanned aircraft systems (sUAS), as platforms for remote sensing, students gathered imagery of historical cultural heritage locations and collected atmospheric data in the urban boundary layer (UBL). Funded in part by the U.S. Embassy in Kosovo, the program shows great promise in reinforcing core learning concepts through practical problem solving in field applications. Furthermore, participants benefit from enhanced collaboration, cultural exposure and civic engagement

Production of cytokines at the operation site

BACKGROUND AND AIM: Cytokines are part of a family of molecules involved in the initiation, control and termination of the events that occurs in wound healing process. Aim of this study was to evaluate the production of some cytokines [interleukin (IL)-6, IL-10, IL-1alpha, IL-1ra, interferon (IFN)-gamma] in the drainage wound fluid from patients undergoing incisional hernia repair. METHODS: Ten female patients with abdominal midline incisional hernia undergoing to surgical repair were included in this study. In all cases a closed suction drain was placed in the wound below the fascia and it was removed on the 4th postoperative day. Wound fluid was collected on the 1st, 2nd, 3rd and 4th day and its amount in each time was recorded. The production of IL-6, IL-10, IL-1alpha, IL-1ra and IFN-gamma were evaluated as quantity produced in 24 hour. RESULTS: In all patients the amount of drain fluid from surgical wound was highest on the 1st day after surgery, afterwards there is a significant reduction. The production of all cytokines evaluated was highest on the 1st day decreasing on the 2nd day except for IL-1alpha that not show any modification. The produciton of IL-1ra, IL-6, IL-1alpha and IL-10 was significantly reduced on the 3rd and 4th postoperative day in comparison with the respectively values recorded on the 1st day, whereas IFN-gamma levels were similar. CONCLUSIONS: The dosage of cytokines in the drain fluid led us to better evaluated the events that follow surgical wound and their analysis offers further information in the role of cytokines in healing process, with the goal to get supportive treatments to promote the best evolution