Establishing the potential for using routine data on Incapacity Benefit to assess the local impact of policy initiatives

<i>Background</i>: Incapacity Benefit (IB) is the key contributory benefit for people who are incapable of work because of illness or disability. <i>Methods</i>: The aims were to establish the utility of routinely collected data for local evaluation and to provide a descriptive epidemiology of the IB population in Glasgow and Scotland for the period 2000–05 using data supplied by the Department for Work and Pensions. <i>Results</i>: Glasgow's IB population is large in absolute and relative terms but is now falling, mainly due to a decrease in on flow. Claimants, tend to be older, have a poor work history and suffer from mental health problems. The rate of decline has been greater in Glasgow than Scotland, although the rate of on flow is still higher. <i>Conclusions</i>: Department for Work and Pensions (DWP) data can be used locally to provide important insights into the dynamics of the IB population. However, to be truly useful, more work needs to be undertaken to combine the DWP data with other information

Comparison of methods for estimating continuous distributions of relaxation times

The nonparametric estimation of the distribution of relaxation times approach is not as frequently used in the analysis of dispersed response of dielectric or conductive materials as are other immittance data analysis methods based on parametric curve fitting techniques. Nevertheless, such distributions can yield important information about the physical processes present in measured material. In this letter, we apply two quite different numerical inversion methods to estimate the distribution of relaxation times for glassy \lila\ dielectric frequency-response data at 225 \kelvin. Both methods yield unique distributions that agree very closely with the actual exact one accurately calculated from the corrected bulk-dispersion Kohlrausch model established independently by means of parametric data fit using the corrected modulus formalism method. The obtained distributions are also greatly superior to those estimated using approximate functions equations given in the literature.Comment: 4 pages and 4 figure

Ion observations from geosynchronous orbit as a proxy for ion cyclotron wave growth during storm times

[1] There is still much to be understood about the processes contributing to relativistic electron enhancements and losses in the radiation belts. Wave particle interactions with both whistler and electromagnetic ion cyclotron (EMIC) waves may precipitate or accelerate these electrons. This study examines the relation between EMIC waves and resulting relativistic electron flux levels after geomagnetic storms. A proxy for enhanced EMIC waves is developed using Los Alamos National Laboratory Magnetospheric Plasma Analyzer plasma data from geosynchronous orbit in conjunction with linear theory. In a statistical study using superposed epoch analysis, it is found that for storms resulting in net relativistic electron losses, there is a greater occurrence of enhanced EMIC waves. This is consistent with the hypothesis that EMIC waves are a primary mechanism for the scattering of relativistic electrons and thus cause losses of such particles from the magnetosphere

Chiral boundary conditions for Quantum Hall systems

A quantum mesoscopic billiard can be viewed as a bounded electronic system due to some external confining potential. Since, in general, we do not have access to the exact expression of this potential, it is usually replaced by a set of boundary conditions. We discuss, in addition to the standard Dirichlet choice, the other possibilities of boundary conditions which might correspond to more complicated physical situations including the effects of many body interactions or of a strong magnetic field. The latter case is examined more in details using a new kind of chiral boundary conditions for which it is shown that in the Quantum Hall regime, bulk and edge characteristics can be described in a unified way.Comment: 16 pages, LaTeX, 2 figures, to be published in the Proceedings of the Minerva workshop on Mesoscopics, Fractals and Neural Networks, Phil. Mag. (1997

Viral proteins expressed in the protozoan parasite Eimeria tenella are detected by the chicken immune system

BACKGROUND: Eimeria species are parasitic protozoa that cause coccidiosis, an intestinal disease commonly characterised by malabsorption, diarrhoea and haemorrhage that is particularly important in chickens. Vaccination against chicken coccidiosis is effective using wild-type or attenuated live parasite lines. The development of protocols to express foreign proteins in Eimeria species has opened up the possibility of using Eimeria live vaccines to deliver heterologous antigens and function as multivalent vaccine vectors that could protect chickens against a range of pathogens. RESULTS: In this study, genetic complementation was used to express immunoprotective virus antigens in Eimeria tenella. Infectious bursal disease virus (IBDV) causes Gumboro, an immunosuppressive disease that affects productivity and can interfere with the efficacy of poultry vaccination programmes. Infectious laryngotracheitis virus (ILTV) causes a highly transmissible respiratory disease for which strong cellular immunity and antibody responses are required for effective vaccination. Genes encoding the VP2 protein from a very virulent strain of IBDV (vvVP2) and glycoprotein I from ILTV (gI) were cloned downstream of 5’Et-Actin or 5’Et-TIF promoter regions in plasmids that also contained a mCitrine fluorescent reporter cassette under control of the 5’Et-MIC1 promoter. The plasmids were introduced by nucleofection into E. tenella sporozoites, which were then used to infect chickens. Progeny oocysts were sorted by FACS and passaged several times in vivo until the proportion of fluorescent parasites in each transgenic population reached ~20 % and the number of transgene copies per parasite genome decreased to < 10. All populations were found to transcribe and express the transgene and induced the generation of low titre, transgene-specific antibodies when used to immunise chickens. CONCLUSIONS: E. tenella can express antigens of other poultry pathogens that are successfully recognised by the chicken immune system. Nonetheless, further work has to be done in order to improve the levels of expression for its future use as a multivalent vaccine vector. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13071-016-1756-2) contains supplementary material, which is available to authorized users

Tuning the effects of Landau-level mixing on anisotropic transport in quantum Hall systems

Electron-electron interactions in half-filled high Landau levels in two-dimensional electron gases in a strong perpendicular magnetic field can lead to states with anisotropic longitudinal resistance. This longitudinal resitance is generally believed to arise from broken rotational invariance, which is indicated by charge density wave (CDW) order in Hartree-Fock calculations. We use the Hartree-Fock approximation to study the influence of externally tuned Landau level mixing on the formation of interaction induced states that break rotational invariance in two-dimensional electron and hole systems. We focus on the situation when there are two non-interacting states in the vicinity of the Fermi level and construct a Landau theory to study coupled charge density wave order that can occur as interactions are tuned and the filling or mixing are varied. We examine in detail a specific example where mixing is tuned externally through Rashba spin-orbit coupling. We calculate the phase diagram and find the possibility of ordering involving coupled striped or triangular charge density waves in the two levels. Our results may be relevant to recent transport experiments on quantum Hall nematics in which Landau-level mixing plays an important role.Comment: 25 pages, 6 figure

Nanoscale Torsional Optomechanics

Optomechanical transduction is demonstrated for nanoscale torsional resonators evanescently coupled to optical microdisk whispering gallery mode resonators. The on-chip, integrated devices are measured using a fully fiber-based system, including a tapered and dimpled optical fiber probe. With a thermomechanically calibrated optomechanical noise floor down to 7 fm/sqrt(Hz), these devices open the door for a wide range of physical measurements involving extremely small torques, as little as 4x10^-20 N*m.Comment: 4 pages, 4 figures - Accepted to APL Oct 22nd, 2012. To appear in February 4th issue - as cover articl

Coordinate shift in the semiclassical Boltzmann equation and the anomalous Hall effect

We propose a gauge invariant expression for the side jump associated with scattering between particular Bloch states. Our expression for the side jump follows from the Born series expansion for the scattering T-matrix in powers of the strength of the scattering potential. Given our gauge invariant side jump expression, it is possible to construct a semiclassical Boltzmann theory of the anomalous Hall effect which expresses all previously identified contributions in terms of gauge invariant quantities and does not refer explicitly to off-diagonal terms in the density-matrix response.Comment: 6 pages, 1 fugure. submitted to PR

Chern-Simons matrix models and Stieltjes-Wigert polynomials

Employing the random matrix formulation of Chern-Simons theory on Seifert manifolds, we show how the Stieltjes-Wigert orthogonal polynomials are useful in exact computations in Chern-Simons matrix models. We construct a biorthogonal extension of the Stieltjes-Wigert polynomials, not available in the literature, necessary to study Chern-Simons matrix models when the geometry is a lens space. We also discuss several other results based on the properties of the polynomials: the equivalence between the Stieltjes-Wigert matrix model and the discrete model that appears in q-2D Yang-Mills and the relationship with Rogers-Szego polynomials and the corresponding equivalence with an unitary matrix model. Finally, we also give a detailed proof of a result that relates quantum dimensions with averages of Schur polynomials in the Stieltjes-Wigert ensemble.Comment: 25 pages, AMS-LaTe