220 research outputs found

    Defining the business ecosystem of peer-to-peer electricity trading

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    Purpose: The purpose of this paper is to introduce the value proposition and structure of the business ecosystem of peer-to-peer electricity trading through a future oriented approach. Design/Methodology/Approach: This study follows a qualitative approach. It conducts conceptual analyses by utilizing previously validated tools in similar contexts. First, different views on business ecosystems are introduced and an argument is made to justify an ecosystem perspective for peerto-peer electricity trading. Second, the value proposition of the peer-to-peer electricity trading ecosystem is identified by utilising a meta-model which consists of four elements: end customer value, business value (shareholder value), collaborative value (business value to the supply chain) and societal value (value creation in the supply chain and control of negative externalities). Third, based on the structural view of business ecosystems, the study identifies actors, positions, links, and activities in the traditional electricity trading. And last, (structural) changes of the ecosystem for peer-to-peer electricity trading are discussed. Findings: This paper elaborates the business ecosystem of peer-to-peer electricity trading and highlights the structural changes it imposes to the status quo. Practical and social implications: The ecosystem construct adds insights into actors’ ecosystem strategy regarding their business models for peer-to-peer electricity trading as well as into the governance of this type of trading. It provides a comprehensive view for policy makers. It enhances the research designs in detailed aspects of the peer-to-peer electricity trading by providing a wide lense. Originality/Value: The identified business ecosystem of peer-to-peer electricity trading provides a comprehensive, multi-stakeholder perspective to incorporate complexities and include externalities

    Proposal for a standard problem for micromagnetic simulations including spin-transfer torque

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    The spin-transfer torque between itinerant electrons and the magnetization in a ferromagnet is of fundamental interest for the applied physics community. To investigate the spin-transfer torque, powerful simulation tools are mandatory. We propose a micromagnetic standard problem includingthe spin-transfer torque that can be used for the validation and falsication of micromagnetic simulation tools. The work is based on the micromagnetic model extended by the spin-transfer torque in continuously varying magnetizations as proposed by Zhang and Li. The standard problem geometry is a permalloy cuboid of 100 nm edge length and 10 nm thickness, which contains a Landau pattern with a vortex in the center of the structure. A spin-polarized dc current density of 1012 A/m2 flows laterally through the cuboid and moves the vortex core to a new steady-state position. We show that the new vortex-core position is a sensitive measure for the correctness of micromagnetic simulatorsthat include the spin-transfer torque. The suitability of the proposed problem as a standard problem is tested by numerical results from four different finite-difference and finite-element-based simulation tools

    Experimental observation of the optical spin transfer torque

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    The spin transfer torque is a phenomenon in which angular momentum of a spin polarized electrical current entering a ferromagnet is transferred to the magnetization. The effect has opened a new research field of electrically driven magnetization dynamics in magnetic nanostructures and plays an important role in the development of a new generation of memory devices and tunable oscillators. Optical excitations of magnetic systems by laser pulses have been a separate research field whose aim is to explore magnetization dynamics at short time scales and enable ultrafast spintronic devices. We report the experimental observation of the optical spin transfer torque, predicted theoretically several years ago building the bridge between these two fields of spintronics research. In a pump-and-probe optical experiment we measure coherent spin precession in a (Ga,Mn)As ferromagnetic semiconductor excited by circularly polarized laser pulses. During the pump pulse, the spin angular momentum of photo-carriers generated by the absorbed light is transferred to the collective magnetization of the ferromagnet. We interpret the observed optical spin transfer torque and the magnetization precession it triggers on a quantitative microscopic level. Bringing the spin transfer physics into optics introduces a fundamentally distinct mechanism from the previously reported thermal and non-thermal laser excitations of magnets. Bringing optics into the field of spin transfer torques decreases by several orders of magnitude the timescales at which these phenomena are explored and utilized.Comment: 11 pages, 4 figure

    Dissecting the transcriptome in cardiovascular disease

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    The human transcriptome comprises a complex network of coding and non-coding RNAs implicated in a myriad of biological functions. Non-coding RNAs exhibit highly organized spatial and temporal expression patterns and are emerging as critical regulators of differentiation, homeostasis, and pathological states, including in the cardiovascular system. This review defines the current knowledge gaps, unmet methodological needs, and describes the challenges in dissecting and understanding the role and regulation of the non-coding transcriptome in cardiovascular disease. These challenges include poor annotation of the non-coding genome, determination of the cellular distribution of transcripts, assessment of the role of RNA processing and identification of cell-type specific changes in cardiovascular physiology and disease. We highlight similarities and differences in the hurdles associated with the analysis of the non-coding and protein-coding transcriptomes. In addition, we discuss how the lack of consensus and absence of standardized methods affect reproducibility of data. These shortcomings should be defeated in order to make significant scientific progress and foster the development of clinically applicable non-coding RNA-based therapeutic strategies to lessen the burden of cardiovascular disease

    Co-creation: Moving towards a framework for creating innovation in the triple helix

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    The objective of the paper is to demonstrate how the theoretical ideas of Service-Dominant Logic (S-D logic) can usefully be applied to innovation through collaboration between university, industry and government. The debate around S-D logic has stimulated much discussion around three areas that are particularly pertinent in considering the co-creation of knowledge within the Triple Helix. The first area relates to understanding the nature of the resources provided by all the parties involved and the process through which they are integrated. The second area relates to interaction between the parties involved. The third and most complex area relates to how value is perceived by the different parties. This discussion leads to a proposed model of the co-creation process and four suggested research agendas: Research Agenda One, relating to the resources supplied by the parties and their integration; Research Agenda Two, concerning the interaction practices that enhance co-creation; Research Agenda Three, exploring what value propositions will motivate the different parties to co-create; and Research Agenda Four, considering how co-creation modifies the resources of the parties involved. A model of the co-creation process that encompasses these four research agendas and provides a conceptual framework to analyse Triple Helix initiatives is proposed. Some practical implications are then discussed, relating to the challenges for researchers in identifying who to co-create with and understanding what value propositions will motivate potential partners

    Contemporary European practice in transcatheter aortic valve implantation:results from the 2022 European TAVI Pathway Registry

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    Background: A steep rise in the use of transcatheter aortic valve implantation (TAVI) for the management of symptomatic severe aortic stenosis occurred. Minimalist TAVI procedures and streamlined patient pathways within experienced Heart Valve Centres are designed to overcome the challenges of ever-increasing procedural volume. Aims: The 2022 European TAVI Pathway Survey aims to describe contemporary TAVI practice across Europe. Materials and methods: Between October and December 2022, TAVI operators from 32 European countries were invited to complete an online questionnaire regarding their current practice. Results: Responses were available from 147 TAVI centres in 26 countries. In 2021, the participating centres performed a total number of 27,223 TAVI procedures, with a mean of 185 TAVI cases per centre (median 138; IQR 77–194). Treatment strategies are usually (87%) discussed at a dedicated Heart Team meeting. Transfemoral TAVI is performed with local anaesthesia only (33%), with associated conscious sedation (60%), or under general anaesthesia (7%). Primary vascular access is percutaneous transfemoral (99%) with secondary radial access (52%). After uncomplicated TAVI, patients are transferred to a high-, medium-, or low-care unit in 28%, 52%, and 20% of cases, respectively. Time to discharge is day 1 (12%), day 2 (31%), day 3 (29%), or day 4 or more (28%). Conclusion: Reported adoption of minimalist TAVI techniques is common among European TAVI centres, but rates of next-day discharge remain low. This survey highlights the significant progress made in refining TAVI treatment and pathways in recent years and identifies possible areas for further improvement.</p
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