5,375 research outputs found
Optimal Energy Allocation For Delay-Constrained Traffic Over Fading Multiple Access Channels
In this paper, we consider a multiple-access fading channel where users
transmit to a single base station (BS) within a limited number of time slots.
We assume that each user has a fixed amount of energy available to be consumed
over the transmission window. We derive the optimal energy allocation policy
for each user that maximizes the total system throughput under two different
assumptions on the channel state information. First, we consider the offline
allocation problem where the channel states are known a priori before
transmission. We solve a convex optimization problem to maximize the
sum-throughput under energy and delay constraints. Next, we consider the online
allocation problem, where the channels are causally known to the BS and obtain
the optimal energy allocation via dynamic programming when the number of users
is small. We also develop a suboptimal resource allocation algorithm whose
performance is close to the optimal one. Numerical results are presented
showing the superiority of the proposed algorithms over baseline algorithms in
various scenarios.Comment: IEEE Global Communications Conference: Wireless Communications
(Globecom2016 WC
What Is a “Substantial Burden” on Religion Under RFRA and the First Amendment?
What is the meaning of a “substantial burden” on religion under the federal Religious Freedom Restoration Act (and its state-level equivalents)? This question is timelier than ever, as several pending cert petitions before the Supreme Court ask it to overturn the landmark decision that spurred RFRA’s enactment: Employment Division v. Smith, which held that exemptions for burdens on religion are not required from neutral and generally applicable laws. Whether or not the Court grants any of these cert petitions, judges will continue to need a clear and reliable method for identifying substantial burdens on religion. This Article considers several existing tests and proposes a new framework designed to remedy their shortcomings.
Put simply, a court’s analysis of a substantial burden requires it to ask two questions: (1) What type of religious exercise does the law burden? And (2) what type of impact does the law have on that exercise? The Article develops answers to both questions, by specifying the kind of religious exercise that can be substantially burdened in the first place (what I’ll call obligation and substantial religious autonomy), and by sketching several types of substantial impact laws might have on religion (what I’ll call simply punitive, indirectly punitive, non-punitive, or preventive burdens). Only burdens that meet these two criteria together can properly be considered substantial. Taken together, these two prongs of the framework help us generate a taxonomy of at least eight different kinds of substantial burdens on religion.
But a challenge remains: Would judicial application of this framework—particularly, would asking what type of religious exercise the law burdens— violate the Establishment Clause? In response, the Article clarifies the kinds of Establishment Clause concerns one might have about any judicial effort to interpret the substantiality of a burden on religion. Ultimately, it finds, the proposed framework can withstand all those concerns. Finally, the Article shows more precisely how the framework would help the Supreme Court decide a number of recent and potentially forthcoming cases involving substantial-burden claims
Charge-Transfer Interactions of Nicotine with Chloranil: Solvent Effects UV-Visible Spectrophotometric Study
UV-visible spectrophotometric studies on the interaction of nicotine with chloranil in cyclohexane, dioxane, benzene, chloroform and dichloromethane solutions at 25 °C demonstrate the formation of charge-transfer (CT) complexes. A new broad band begins to grow in time on the longer wavelength side of the characteristic absorption bands of the constituents. At equilibrium, the new band position depends on the polarity of the solvent used. In EtOH, MeOH and DMSO solutions, a new absorption spectra are immediately formed after mixing. The position of the new spectra is not affected by the solvent polarity. The solvation of the CT-complex immediately causes complete ionization of the neutral complex. It has been found that acetone acts as intermediate between the non-ionizing and ionizing solvents in which absorptions corresponding to the ions are observed simultaneously with the intermolecular CT-absorption. The stability constants and the molar absorptivities of the complexes formed have been calculated assuming the formation of 1 :1 complexes. Experimental results indicate that the stability constant of the complex formed and its type (neutral or ionic) depends greatly on the dielectric constant of the solvent used
Proactive Location-Based Scheduling of Delay-Constrained Traffic Over Fading Channels
In this paper, proactive resource allocation based on user location for
point-to-point communication over fading channels is introduced, whereby the
source must transmit a packet when the user requests it within a deadline of a
single time slot. We introduce a prediction model in which the source predicts
the request arrival slots ahead, where denotes the prediction
window (PW) size. The source allocates energy to transmit some bits proactively
for each time slot of the PW with the objective of reducing the transmission
energy over the non-predictive case. The requests are predicted based on the
user location utilizing the prior statistics about the user requests at each
location. We also assume that the prediction is not perfect. We propose
proactive scheduling policies to minimize the expected energy consumption
required to transmit the requested packets under two different assumptions on
the channel state information at the source. In the first scenario, offline
scheduling, we assume the channel states are known a-priori at the source at
the beginning of the PW. In the second scenario, online scheduling, it is
assumed that the source has causal knowledge of the channel state. Numerical
results are presented showing the gains achieved by using proactive scheduling
policies compared with classical (reactive) networks. Simulation results also
show that increasing the PW size leads to a significant reduction in the
consumed transmission energy even with imperfect prediction.Comment: Conference: VTC2016-Fall, At Montreal-Canad
Cell Surface Expression of the Vaccinia Virus Complement Control Protein is Mediated by Interaction with the Viral A56 Protein and Protects Infected Cells from Complement Attack
The vaccinia virus (VACV) complement control protein (VCP) is the major protein secreted from VACV-infected cells. It has been reported that VCP binds to the surfaces of uninfected cells by interacting with heparan sulfate proteoglycans (HSPGs). In this study, we show that VCP is also expressed on the surfaces of infected cells and demonstrate that surface localization occurs independently of HSPGs. Since VCP does not contain a transmembrane domain, we hypothesized that VCP interacts with a membrane protein that localizes to the infected-cell surface. We show that the VACV A56 membrane protein is necessary for the cell surface expression of VCP and demonstrate that VCP and A56 interact in VACV-infected cells. Since the surface expression of VCP was abrogated by reducing agents, we examined the contribution of an unpaired cysteine residue on VCP to VCP surface expression and VCP\u27s interaction with A56. To do this, we mutated the unpaired cysteine in VCP and generated a recombinant virus expressing the altered form of VCP. Following the infection of cells with the mutant virus, VCP was neither expressed on the cell surface nor able to interact with A56. Importantly, the cell surface expression of VCP was found to protect infected cells from complement-mediated lysis. Our findings suggest a new function for VCP that may be important for poxvirus pathogenesis and impact immune responses to VACV-based vaccines
Pancreatic beta-cell failure in the pathogenesis of type 2 diabetes
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