24,792 research outputs found

    The Media, Risk Assessment and Numbers: They Don\u27t Add Up

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    Professor Friedman argues that, for risks to be reported accurately, journalism educators must help their students understand science, numbers and statistics

    Learning OT constraint rankings using a maximum entropy model

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    Abstract. A weakness of standard Optimality Theory is its inability to account for grammar

    The effect of a cardiovascular risk factor education program on health behaviors of selected school age children

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    This study, using a quasi-experimental design, was conducted to explore the effect of a cardiovascular risk factor education program on the health behaviors of a group of fifth grade children. The following hypothesis was tested: There will be a statistically significant improvement in self-reported health behaviors of school age children who receive a cardiovascular risk factor education program as compared to the self-reported health behaviors of those school age children who do not receive a cardiovascular risk factor education program. One hundred and nineteen subjects, 63 in the experimental group and 56 in the control group, were tested using the researcher\u27s designed health behavior questionnaire, My Health Behaviors , before and after participation in the health education program. The program provided for the experimental group consisted of eight 45 minute sessions. The introductory and summary sessions were primarily concerned with administration of the pretest and post-test and sessions two through seven were informative sessions about high fat, high cholesterol diet, smoking and sedentary lifestyle. The program provided for the control group consisted of four 45 minute sessions; session one was concerned with introductory material and administration of the pre-test, sessions two and three were informative sessions related to general nutrition and foods high in salt and sugar, and session four was devoted to review of content as well as administration of the post—test. Data were statistically analyzed using the paired-sample student\u27s t-test. Results of the analysis revealed a significant difference between the two sample groups at p\u3c0.01 level. The hypothesis was accepted

    Effector Caspase Dcp-1 and IAP Protein Bruce Regulate Starvation-Induced Autophagy during Drosophila Melanogaster Oogenesis

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    A complex relationship exists between autophagy and apoptosis, but the regulatory mechanisms underlying their interactions are largely unknown. We conducted a systematic study of Drosophila melanogaster cell death–related genes to determine their requirement in the regulation of starvation-induced autophagy. We discovered that six cell death genes—death caspase-1 (Dcp-1), hid, Bruce, Buffy, debcl, and p53—as well as Ras–Raf–mitogen activated protein kinase signaling pathway components had a role in autophagy regulation in D. melanogaster cultured cells. During D. melanogaster oogenesis, we found that autophagy is induced at two nutrient status checkpoints: germarium and mid-oogenesis. At these two stages, the effector caspase Dcp-1 and the inhibitor of apoptosis protein Bruce function to regulate both autophagy and starvation-induced cell death. Mutations in Atg1 and Atg7 resulted in reduced DNA fragmentation in degenerating midstage egg chambers but did not appear to affect nuclear condensation, which indicates that autophagy contributes in part to cell death in the ovary. Our study provides new insights into the molecular mechanisms that coordinately regulate autophagic and apoptotic events in vivo.Canadian Institutes of Health (MOP-78882); National Institutes of Health (R01 GM60574); Summer Undergraduate Research Fellowship program at Boston University; National Science Foundation (0450339

    Determinants Associated to Zeta Matrices of Posets

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    We consider the matrix ZP=ZP+ZPt{\frak Z}_P=Z_P+Z_P^t, where the entries of ZPZ_P are the values of the zeta function of the finite poset PP. We give a combinatorial interpretation of the determinant of ZP{\frak Z}_P and establish a recursive formula for this determinant in the case in which PP is a boolean algebra.Comment: 14 pages, AMS-Te

    Cigarette smoking and the desire to quit among individuals living with HIV

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    Among individuals living with human immunodeficiency virus (HIV), studies have found that smokers are at greater risk than nonsmokers to develop bacterial pneumonia, oral lesions and acquired immune deficiency syndrome (AIDS) dementia complex. Information is lacking regarding the prevalence of cigarette smoking among people living with HIV or about their intentions to quit smoking. A survey was conducted with a sample of patients attending an HIV outpatient clinic at San Francisco General Hospital to assess the prevalence of cigarette smoking and the level of interest in quitting. In total, 228 assessments were completed. Study results revealed a high percentage of smokers among our sample of individuals living with HIV compared to the percentage of smokers found in the general adult population. A total of 123 individuals (54%) reported that they smoked cigarettes. Men were more than twice as likely to have made previous attempts at smoking cessation than were woman. The majority of cigarette smokers (63%) reported that they were currently thinking about quitting. Respondents\u27 preferences for types of smoking cessation methods are discussed, and recommendations are proposed for identifying and treating tobacco dependence in this population
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