Determination of Some Selected Physical Properties of Different Maize Varieties (Zea Mays) Related to Design of Processing Machines of Nigeria

Abstract: The design related physical properties of six-selected Improved Institute for Agricultural Research Maize varieties were investigated. The properties will enhance design and development of production, processing and storage equipment for the crop. The mean results obtained for the different collections ranged from 7.42 to 15.63%, 8.2mm to 10.4mm, 7.1 to 9.1mm, 4.0mm to 5.0mm, 6.6mm to 7.2mm, 133mm2to 161mm2, 0.62% to 0.81%, 0.46% to0.82%, 692.42kg/m3to 747.86kg/m3, 1162.54kg/m3 to1447.7kg/m3,37.79%to 46.69%, 203.62g to 306.86g, 170.09mm3to 234.59mm3, 35.8

Scalar Pair Production in the Aharonov-Bohm Potential

In the framework of QED, scalar pair production by a single linearly polarized high-energy photon in the presence of an external Aharonov-Bohm potential is investigated. The exact scattering solutions of the Klein-Gordon equation in cylindrically symmetric field are constructed and used to write the first order transition amplitude. The matrix elements and the corresponding differential scattering cross-section are calculated. The pair production at both the nonrelativistic and the ultrarelativistic limits is discussed.Comment: 13 pages, 1 figur

Identification of a variant hotspot in MYBPC3 and of a novel CSRP3 autosomal recessive alteration in a cohort of Polish patients with hypertrophic cardiomyopathy

INTRODUCTION Hypertrophic cardiomyopathy (HCM) is a heart disorder caused by autosomal dominant alterations affecting both sarcomeric genes and other nonsarcomeric loci in a minority of cases. However, in some patients, the occurrence of the causal pathogenic variant or variants in homozygosity, compound heterozygosity, or double heterozygosity has also been described. Most of the HCM pathogenic variants are missense and unique, but truncating mutations of the MYBPC3 gene have been reported as founder pathogenic variants in populations from Finland, France, Japan, Iceland, Italy, and the Netherlands. OBJECTIVES This study aimed to assess the genetic background of HCM in a cohort of Polish patients. PATIENTS AND METHODS Twenty–nine Polish patients were analyzed by a next–generation sequencing panel including 404 cardiovascular genes. RESULTS Pathogenic variants were found in 41% of the patients, with ultra–rare MYBPC3 c.2541C>G (p.Tyr847Ter) mutation standing for a variant hotspot and correlating with a lower age at HCM diagnosis. Among the nonsarcomeric genes, the CSRP3 mutation was found in a single case carrying the novel c.364C>T (p.Arg122Ter) variant in homozygosity. With this finding, the total number of known HCM cases with human CSRP3 knockout cases has reached 3

Perturbative Study of Bremsstrahlung and Pair-Production by Spin-1/2 Particles in the Aharonov-Bohm Potential

In the presence of an external Aharonov-Bohm potential, we investigate the two QED processes of the emission of a bremsstrahlung photon by an electron, and the production of an electron-positron pair by a single photon. Calculations are carried out using the Born approximation within the framework of covariant perturbation theory to lowest non-vanishing order in \alpha. The matrix element for each process is derived, and the corresponding differential cross-section is calculated. In the non-relativistic limit, the resulting angular and spectral distributions and some polarization properties are considered, and compared to results of previous works.Comment: 15 pages, RevTex 4, 2 figures, submitted for publicatio

Perturbations of Gauss-Bonnet Black Strings in Codimension-2 Braneworlds

We derive the Lichnerowicz equation in the presence of the Gauss-Bonnet term. Using the modified Lichnerowicz equation we study the metric perturbations of Gauss-Bonnet black strings in Codimension-2 Braneworlds.Comment: 26 pages, no figures, clarifying comments and one reference added, to be published in JHE

The Seduction of Thanatos : Gabriele D’Annunzio and the Decadent Death

Peer reviewe

Novel and recurrent p14(ARF) mutations in Italian familial melanoma

CDKN2A and CDK4 are the only known high-penetrant genes conferring proneness to cutaneous melanoma. The CDKN2A locus consists of four exons and encodes several alternate transcripts, two of which are p16(INK4a) and p14(ARF), and originate from different open reading frames. Exon 1 alpha is specific for p16(INK4a), while exon 1 beta characterizes p14(ARF). Most CDKN2A mutations are located in exons 1 alpha and 2, while exon 1 beta variations have been identified in rare melanoma-prone pedigrees. In a previous study, we investigated 155 Italian melanoma cases, including 94 familial melanomas (FAMs) and 61 sporadic multiple primary melanomas (MPMs), for p16(INK4a)/CDK4 germline alterations and identified 15 p16(INK4a) and 1 CDK4 point mutations. In the present work, we extended our search to p14(ARF) mutations and CDKN2A deletions in the remaining samples. We identified the recurrent g.193+1G>A mutation in two FAM cases, while an additional pedigree displayed the previously undescribed variant g.161G>A. Multiplex ligation-dependent probe amplification (MLPA) screening for copy variations resulted negative in all cases. In Italy, the overall frequency of p14(ARF) mutations is 3.2% in FAM and 0% in sporadic MPM. Re-evaluation of our patients' cohort emphasizes that the chance of identifying CDKN2A/CDK4 mutations in FAM is mainly influenced by the number of affected family members and the presence of one or more MPM cases. Accordingly, mutation rate rises to 61% in selected cases. Further studies are expected in order to investigate CDKN2A rarer mutations, including atypical deletions and inherited epimutations

Screening of mutations in the CFTR gene in 1195 couples entering assisted reproduction technique programs.

Genetic testing of the cystic fibrosis transmembrane conductance (CFTR) gene is currently performed in couples undergoing assisted reproduction techniques (ART), because of the high prevalence of healthy carriers in the population and the pathogenic relationship with congenital bilateral absence of vas deferens (CBAVD). However, discordant data have been reported concerning the usefulness of this genetic test in couples with no family history of cystic fibrosis (CF). In this study, we report the results of CFTR molecular screening in 1195 couples entering ART. Genetic testing was initially carried out in a single partner of each couple. CFTR mutations were detected in 55 subjects (4.6%), a percentage that overlaps with the one reported in the general population. However, significantly higher frequencies of were found in CBAVD individuals (37.5%) and in males with nonobstructive azoospermia (6.6%). The 5T allele was found in 78 patients (6.5%). This figure was again significantly different in males with nonobstructive-azoospermia (9.9%) and in those with CBAVD (100%). All together, 139 subjects (11.6%) had either a CFTR mutation or the 5T allele. Subsequent molecular analysis of their partners disclosed a CFTR mutation or 5T allele in nine cases (6.5%). However, none of these couples had CFTR alterations in both members, a CFTR mutation being invariably present in one partner and the 5T allele in the other. In order to improve genetic counselling of these couples, the TG-M470V-5T association was analyzed, and a statistically significant relationship between 12TG-V470 and CBAVD was detected