1,573 research outputs found

    Interloper: Activating the Possible

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    This article seeks to open a dialogue on encouraging creative possibility in architectural education, with particular focus on the architecture studio. Although discussed through the practice of design, I present experimental methods that are adaptable across creative and speculative disciplines. Rooted in the conceptual difference between possible and probable thinking as identified by philosophers Didier Debaise and Isabelle Stengers, this article positions the role of the architect as being interstitially located in multiple temporalities (as well as occupying the liminal space between the real and the imagined) in such a way that this difference between possible and probable is seen to be potentially critical to the future of the built environment. Focusing on non-linear time (investigated through temporal mapping), situating the imagined architecture in the dynamic conditions of site (site studies/development of architecture), and through the introduction of an interloper (chance/event), this article acts as a framework for examining potential methods for nurturing and sustaining possibility in the space of the architecture studio

    Regulation of inositol polyphosphate metabolism in airways smooth muscle

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    The Awakening: Empowered by water what are the personal and political implications for female activists in the Irish Anti-Water charges movement?

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    This research seeks to identify what are the personal and political implications for female activist in the Irish anti-water charges movement? While this movement is not a women-only organisation, nor is it concerned with gender-specific issues, the key findings in this research will demonstrate an astute and growing political awareness among women and a determined commitment to active political engagement. While this has not yet awakened any great ambition for these women to enter the structural political arena, their desire to have systematic and cultural change in Irish politics may hold the key for fuller female participation in the future. This thesis will argue that women are such a powerful resource to the anti-water charges movement; they can greatly influence and shape the organisations political goals. If the women‟s concerns and objectives are genuinely taken on board by the broader movement, there could be a popular push for a more accountable political system and culture that also facilitates women to take their place equally alongside men in Irish politics. Rather than trying to „fit‟ women into the current political system via gender-quotas, a change in system and culture, proposed and endorsed by women, may attract more able females into the Irish political arena by default. In order for the movement to embrace these concerns, it also has to organisationally demonstrate internal participatory practices and a culture that values and recognises the key contribution these women make

    A Survey of Analogs to Weak MgII Absorbers in the Present

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    We present the results of a survey of the analogs of weak MgII absorbers (rest frame equivalent width W(2796) < 0.3 A) at 0 < z < 0.3. Our sample consisted of 25 HST/STIS echelle quasar spectra (R = 45,000) which covered SiII 1260 and CII 1335 over this redshift range. Using those similar transitions as tracers of MgII facilitates a much larger survey, covering a redshift pathlength of g(z) = 5.3 for an equivalent width limit of MgII corresponding to W(2796) > 0.02 A, with 30% completeness for the weakest lines. We find the number of weak MgII absorber analogs with 0.02 < W(2796) < 0.3 to be dN/dz = 1.00 +/- 0.20 for 0 < z < 0.3. This value is consistent with cosmological evolution of the population. We consider the expected effect on observability of weak MgII absorbers of the decreasing intensity of the extragalactic background radiation eld from z~1 to z~0. Assuming that all the objects that produce absorption at z~1 are stable on a cosmological timescale, and that no new objects are created, we would expect dN/dz of 2-3 at z~0. About 30-50% of this z~0 population would be decendants of the parsec-scale structures that produce single-cloud, weak MgII absorbers at z~1. The other 50-70% would be lower density, kiloparsec-scale structures that produce CIV absorption, but not detectable low ionization absorption, at z~1. We conclude that at least one, and perhaps some fraction of both, of these populations has evolved away since z~1, in order to match the z~0 dN/dz measured in our survey. This would follow naturally for a population of transient structures whose generation is related to star-forming processes, whose rate has decreased since z~1.Comment: 45 pages, 12 figures, 7 tables ApJ accepte

    Redbird Buzz Episode 23: Jane Lynch, May 1, 2023

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    Interview with Illinois State University alum Jane Lynch, who is an award-winning actor, comedian, author, producer, and singer. The interview was conducted by Rachel Kobus from Alumni Engagement on May 1, 2023, for the Illinois State University Redbird Buzz podcast

    HNPCC (Lynch Syndrome): Differential Diagnosis, Molecular Genetics and Management - a Review

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    HNPCC (Lynch syndrome) is the most common form of hereditary colorectal cancer (CRC), wherein it accounts for between 2-7 percent of the total CRC burden. When considering the large number of extracolonic cancers integral to the syndrome, namely carcinoma of the endometrium, ovary, stomach, hepatobiliary system, pancreas, small bowel, brain tumors, and upper uroepithelial tract, these estimates of its frequency are likely to be conservative. The diagnosis is based upon its natural history in concert with a comprehensive cancer family history inclusive of all anatomic sites. In order for surveillance and management to be effective and, indeed, lifesaving, among these high-risk patients, the linchpin to cancer control would be the physician, who must be knowledgeable about hereditary cancer syndromes, their molecular and medical genetics, genetic counseling, and, most importantly, the natural history of the disorders, so that the entirety of this knowledge can be melded to highly-targeted management
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