First investigation on the applicability of an active noise control system on a tracked tractor without cab

In last years, several research teams pointed their attention on the application of active noise control systems (ANC) inside the cabs of agricultural tractor, with the purpose of reducing the driver exposition to noise, that is only partially controlled by the frame of the cab. This paper reports the results of a first experience that aimed at verifying the applicability of an ANC on a medium-high power, tracked tractor without cab. The tested tractor was a Fiat Allis 150 A, equipped with rear power take off, used in the execution of deep primary tillage in compact soils. It is a tracked tractor without cab, with maximum power of 108.8 kW at 1840 min–1 of the engine. The ANC consists of a control unit box based on a digital signal processor (DPS), two microphones, two speakers and a power amplifier. The instrumentation used in noise data collecting and processing consisted of a multichannel signal analyzer (Sinus - Soundbook), a ½” microphone capsule and an acoustic calibrator, both Bruel & Kjaer. The study aimed at evaluating the behaviour of the ANC by means of tests carried out under repeatable conditions, characterized by pre-defined engine speed values. Three replications have been made for each engine speed. The sampling time was 30 s. Two series of tests were performed in order to compare the results observed with the ANC on and off. The engine speed adopted in the study ranged from 600 min– 1, up to 2000 min–1 (maximum speed) with steps of 100 min–1. The ANC proved to be effective in the interval of speed between 1400 and 1700 min–1, where the samplings have been intensified, adopting steps of 50 min–1. In such an interval, the attenuation observed with the ANC system on appeared evident both as weighed A sound pressure level (from 1.29 up to 2.46 dB(A)) and linear (from 4.54 up to 8.53 dB). The best performance has been observed at the engine speed of 1550 min–1, with attenuations, respectively of 2.46 dB(A) and 7.67 dB. Outside of the engine speed interval 1400 - 1700 min–1, the attenuations always resulted lower than 1 dB(A) for the weighed A sound pressure level and between 0.66 and 7.72 dB

MicroRNA expression is associated with auditory dysfunction in workers exposed to ototoxic solvents and noise

This study is part of a project on early hearing dysfunction induced by combined exposure to volatile organic compounds (VOCs) and noise in occupational settings. In a previous study, 56 microRNAs were found differentially expressed in exposed workers compared to controls. Here, we analyze the statistical association of microRNA expression with audiometric hearing level (HL) and distortion product otoacoustic emission (DPOAE) level in that subset of differentially expressed microRNAs. The highest negative correlations were found; for HL, with miR-195-5p and miR-122-5p, and, for DPOAEs, with miR-92b-5p and miR-206. The homozygous (mut) and heterozygous (het) variants of the gene hOGG1 were found disadvantaged with respect to the wild-type (wt), as regards the risk of hearing impairment due to exposure to VOCs. An unsupervised artificial neural network (auto contractive map) was also used to detect and show, using graph analysis, the hidden connections between the explored variables. These findings may contribute to the formulation of mechanistic hypotheses about hearing damage due to co-exposure to noise and ototoxic solvents

Attenuation of peak sound pressure levels of shooting noise by hearing protective earmuffs

Transmission losses (TL) to highly impulsive signals generated by three firearms have been measured for two ear muffs, using both a head and torso simulator and a miniature microphone located at the ear canal entrance (MIRE technique). Peak SPL TL have been found to be well approximated by 40 ms short-L eq TL. This has allowed the use of transmissibilities and correction factors for bone conduction and physiological masking appropriate for continuous noise, for the calculation of REAT-type peak insertion losses (IL). Results indicate that peak IL can be well predicted by estimates based on one-third octave band 40 ms short L eq and manufacturer-declared (nominal) IL measured for continuous noise according to test standards. Such predictions tend to be more accurate at the high end of the range, while they are less reliable when the attenuation is lower. A user-friendly simplified prediction algorithm has also been developed, which only requires nominal IL and one-third octave sound exposure level spectra. Separate predictions are possible for IL in direct and diffuse sound fields, albeit with higher uncertainties, due to the smaller number of experimental data comprising the two separate datasets on which such predictions are based

Intensimetric detection of distortion product otoacoustic emissions with ear canal calibration

Distortion product otoacoustic emissions (DPOAEs) have been accurately measured with an intensimetric technique, involving simultaneous measure of pressure and velocity in the ear canal, which allows one to correctly calibrate both the input stimuli and the otoacoustic emission (OAE) level. Suitable combinations of standard intensimetric quantities, active intensity and power density [Stanzial, Shiffrer, and Sacchi, J. Acoust. Soc. Am. 131, 269-280 (2012)], are used to equalize the stimuli transmitted to the middle ear, and to estimate the DPOAE level emitted by the eardrum. The DPOAE intensimetric spectra are consistent with those recorded with a high-quality conventional otoacoustic probe with state-of-the-art calibration of both stimulus and OAE response [Charaziak and Shera, J. Acoust. Soc. Am. 141, 515-525 (2017)], demonstrating the applicability of the intensimetric method to OAE measurements

Multimodality approach in presurgical evaluation of epilepsy

Introduction: Both Electroencephalography-functional Magnetic Resonance Imaging (EEG-fMRI) coregistration and high density EEG (hdEEG) map abnormal brain activation elicited by epileptic processes. EEG-fMRI is an imaging technique which provides localizing Blood Oxygenation Level Dependent (BOLD) information of irritative regions. Conversely, the source analysis estimates the current density of the source that generates a measured electric potential. Objectives: Clinical assessment of these techniques is done in patients with focal epilepsy who subsequently underwent epilepsy surgery. Methods: The standard EEG (32 electrodes) and the fMRI data were acquired during a scanning session (1.5T). The hdEEG recording was performed using 256 channels. Each patient underwent to a 3T scan to create a constraint for the source localization. The analysis of EEG-fMRI data was performed by using both the conventional (General Linear Model, GLM) and a novel method, which integrates in the conventional one two new modules: individual-based hemodynamic response function, and EEG protocol. Source localization of interictal epileptiform discharges (IEDs) using 32 (EEG acquired inside the magnet) and 256 EEG channels was calculated. Results: Changes in BOLD signal were observed in 22 out of 30 patients in whom IEDs are recorded. In 82%, these are concordant with expected epileptic activity defined by EEG and clinical outcome. The remaining 8 patients had no significant BOLD activity because of either technical prob- lems or no interictal epileptiform EEG activity inside the scanner. Three patients with activation were selected to underwent a hdEEG and showed significant source localization correlating with the EEG-fMRI activation. Conclusions: The combination of multimodality techniques such as EEG- fMRI coregistration and hdEEG is a useful tool of a presurgical workup of epilepsy providing two different methods of localization of the same epileptic foci

A multimodal imaging approach to the evaluation of post-traumatic epilepsy

Electroencephalography-functional magnetic resonance imaging (EEG-fMRI) coregistration and high-density EEG (hdEEG) can be combined to map noninvasively abnormal brain activation elicited by epileptic processes. By combining noninvasive imaging techniques in a multimodal approach, we sought to investigate pathophysiological mechanisms underlying epileptic activity in seven patients with severe traumatic brain injury

Reproducibility of EEG-fMRI results in a patient with fixation-off sensitivity

Blood oxygenation level-dependent (BOLD) activation associated with interictal epileptiform discharges in a patient with fixation-off sensitivity (FOS) was studied using a combined electroencephalography-functional magnetic resonance imaging (EEG-fMRI) technique. An automatic approach for combined EEG-fMRI analysis and a subject-specific hemodynamic response function was used to improve general linear model analysis of the fMRI data. The EEG showed the typical features of FOS, with continuous epileptiform discharges during elimination of central vision by eye opening and closing and fixation; modification of this pattern was clearly visible and recognizable. During all 3 recording sessions EEG-fMRI activations indicated a BOLD signal decrease related to epileptiform activity in the parietal areas. This study can further our understanding of this EEG phenomenon and can provide some insight into the reliability of the EEG-fMRI technique in localizing the irritative zone