Per què un grup d'homes contra la violència masclista

Abstract not availabl

Memòria Digital de Catalunya

Localització: Barcelona, Biblioteca de l'Ateneu Barcelonès, ms. 322Núm. 703, a la port.Còpia de representacióPaper pautatAcotacions i aparts indicats entre parèntesi

Texture descriptors applied to digital mammography

Breast cancer is the second cause of death among women cancers. Computer Aided Detection has been demon- strated an useful tool for early diagnosis, a crucial as- pect for a high survival rate. In this context, several re- search works have incorporated texture features in mam- mographic image segmentation and description such as Gray-Level co-occurrence matrices, Local Binary Pat- terns, and many others. This paper presents an approach for breast density classi¯cation based on segmentation and texture feature extraction techniques in order to clas- sify digital mammograms according to their internal tis- sue. The aim of this work is to compare di®erent texture descriptors on the same framework (same algorithms for segmentation and classi¯cation, as well as same images). Extensive results prove the feasibility of the proposed ap- proach.Postprint (published version

Onto-Trauma : Ontologia d'aprenentatge en l'àrea de la cirurgia traumatològica

Treball en què es crea una ontologia per simular totes les etapes d'una operació traumatològica, i usa aquesta ontologia per crear un prototip de wiki semàntica.Trabajo en el que se crea una ontología para simular todas las etapas de una operación traumatológica, y usa esta ontología para crear un prototipo de wiki semántica

Aplicación web para la gestión de una base de datos pública de mamografía digital: MamoDB

Cada vez son más los hospitales que disponen de sistemas computarizados de adquisición y visualización de imágenes digitales , con las ventaj as que ello supone cu anto a acceso a la información , capacidad de diagnóstico y aprendizaje . Sin embargo, el volumen ingente de datos requiere de nuevas herramientas para su alm acenaje, gestión y recuperación . En este trabajo se propone un modelo de estructura basado en tecnol ogía web como herramienta de ayuda al diagnóstico de Cáncer de Mama. La estructura propuesta se basa en la administración de imágenes y estudios mamográfico s con el objetivo de ser un referente en la comunidad científica. Su arquitectura, metodología y aplicación en formato web se presentan en es te trabajo así como conclusiones y trabajos futurosPostprint (published version

Improvement in arsenic adsorption and calcite dissolution kinetics through size reduction of a ferric hydroxide-calcite adsorbent

The employment of granular ferric iron-(oxy)hydroxides, a well-known economic and effective method, lowers arsenic concentrations in different water types. However, for direct application in polluted groundwaters, there is a need to develop new injectable adsorbents for aquifers that could also neutralize acidic media. In this context, a granular ferric hydroxide-calcite (GFH-C) adsorbent was size-reduced to 0.4–50 µm by sonication with the aim of improving (i) the adsorption of As(III) and As(V) at different pHs and (ii) the pH control through the dissolution of calcite. Batch experiments were conducted to determine As(III) and As(V) adsorption isotherms and kinetics, as well as calcite dissolution kinetics, using GFH-C of two sizes (granular and sonicated). Results showed that the arsenic binding capacity of sonicated adsorbents did not improve significantly. On the contrary, the As(III) and As(V) adsorption kinetics improved with the sonication, as in the case of calcite dissolution kinetics. The dissolution of calcite from the adsorbent made the water pH increase to around 9.2–9.4. The sonicated adsorbent offers an advantage in depolluting As-containing groundwater due to its smaller size, which is linked with faster arsenic adsorption and effective acidic water neutralization.Peer ReviewedObjectius de Desenvolupament Sostenible::6 - Aigua Neta i SanejamentPostprint (published version

GPER and ERα mediate estradiol enhancement of mitochondrial function in inflamed adipocytes through a PKA dependent mechanism.

Obesity is associated with inflammation, dysregulated adipokine secretion, and disrupted adipose tissue mitochondrial function. Estradiol (E2) has been previously reported to increase mitochondrial function and biogenesis in several cell lines, but neither the type of oestrogen receptor (ERα, ERβ and GPER) involved nor the mechanism whereby such effects are exerted have been fully described. Considering the anti-inflammatory activity of E2 as well as its effects in enhancing mitochondrial biogenesis, the aim of this study was to investigate the contribution of ERα, ERβ, and GPER signaling to the E2-mediated enhancement of adipocyte mitochondrial function in a pro-inflammatory situation. 3T3-L1 cells were treated for 24 h with ER agonists (PPT, DPN, and G1) and antagonists (MPP, PHTPP, and G15) in the presence or absence of interleukin 6 (IL6), as a pro-inflammatory stimulus. Inflammation, mitochondrial function and biogenesis markers were analyzed. To confirm the involvement of the PKA pathway, cells were treated with a GPER agonist, a PKA inhibitor, and IL6. Mitochondrial function markers were analyzed. Our results showed that activation of ERα and GPER, but not ERβ, was able to counteract the proinflammatory effects of IL6 treatment, as well as mitochondrial biogenesis and function indicators. Inhibition of PKA prevented the E2- and G1-associated increase in mitochondrial function markers. In conclusion E2 prevents IL6 induced inflammation in adipocytes and promotes mitochondrial function through the combined activation of both GPER and ERα. These findings expand our understanding of ER interactions under inflammatory conditions in female rodent white adipose tissue

The Palma Echo Platform: Rationale and Design of an Echocardiography Core Lab

Background: The metabolic syndrome (MetS) is associated with increased cardiovascular morbidity and mortality. Characterization of cardiac structural and functional abnormalities due to the MetS can help recognize individuals who would benefit the most from preventive interventions. Transthoracic echocardiography (TTE) provides an opportunity to identify those abnormalities in a reproducible and cost-efficient manner. In research settings, implementation of protocols for the acquisition and analysis of TTE images are key to ensure validity and reproducibility, thus facilitating answering relevant questions about the association of the MetS with cardiac alterations. Methods and Results: The Palma Echo Platform (PEP) is a coordinated network that is built up to evaluate the underlying structural and functional cardiac substrate of participants with MetS. Repeated TTE will be used to evaluate 5-year changes in the cardiac structure and function in a group of 565 individuals participating in a randomized trial of a lifestyle intervention for the primary prevention of cardiovascular disease. The echocardiographic studies will be performed at three study sites, and will be centrally evaluated at the PEP core laboratory. Planned analyses will involve evaluating the effect of the lifestyle intervention on cardiac structure and function, and the association of the MetS and its components with changes in cardiac structure and function. Particular emphasis will be placed on evaluating parameters of left atrial structure and function, which have received more limited attention in past investigations. This PEP will be available for future studies addressing comparable questions. Conclusion: In this article we describe the protocol of a central echocardiography laboratory for the study of functional and structural alterations of the MetS.Research reported in this publication was supported by the National Heart, Lung, and Blood Institute of the National Institutes of Health under Award Numbers R01HL137338 and K24HL148521, and administrative supplement to promote diversity 3R01HL137338-03S1. This work was supported by the official Spanish Institutions for funding scientific biomedical research, CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN) and Instituto de Salud Carlos III (ISCIII), through the Fondo de Investigación para la Salud (FIS), which was co-funded by the European Regional Development Fund (PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI14/00972, PI14/00728, PI14/01471, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926, PI19/00957, PI19/00386, PI19/00309, PI19/01032, PI19/00576, PI19/00017, PI19/01226, PI19/00781, PI19/01560, PI19/01332, PI20/01802, PI20/00138, PI20/01532, PI20/00456, PI20/00339, PI20/00557, PI20/00886, and PI20/01158); the Especial Action Project entitled: Implementación y evaluación de una intervención intensiva sobre la actividad física Cohorte PREDIMED-Plus; the European Research Council (Advanced Research Grant 2014–2019; agreement #340918); the Recercaixa (number 2013ACUP00194); grants from the Consejería de Salud de la Junta de Andalucía (PI0458/2013, PS0358/2016, PI0137/2018); the PROMETEO/2017/017 grant from the Generalitat Valenciana; the SEMERGEN grant; none of the funding sources took part in the design, collection, analysis, interpretation of the data, or writing the report, or in the decision to submit the manuscript for publication